Bioquímica i Fisiologia: Recent submissions
Now showing items 61-80 of 634
Therapeutic applications of essential oils from native and cultivated ecuadorian plants: Cutaneous candidiasis and dermal anti-inflammatory activity
Abstract: Essential oils are a complex mixture of aromatic substances whose pharmacological actions, including antimicrobial, antioxidant, anticancer, and anti-inflammatory activities, have been widely reported. This study ...
Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.
Recent data suggest that ghrelin exerts its orexigenic action through regulation of hypothalamic AMP-activated protein kinase (AMPK) pathway, leading to a decline in malonyl-CoA levels and desinhibition of carnitine ...
Spray dried plasma as an alternative to antibiotics in piglet feeds, mode of action and biosafety
The use of growth promoting and therapeutic antibiotics in piglet feed has been a concerning subject over the last few decades because of the risk of generating antimicrobial resistance that could be transferred to humans. ...
New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines
Many strategies for treating diseases require the delivery of drugs into the cell cytoplasm following internalization within endosomal vesicles. Thus, compounds triggered by low pH to disrupt membranes and release endosomal ...
Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) patients frequently show autonomic symptoms which may be associated with a hypothalamic dysfunction. This study aimed to explore circadian rhythm patterns in rest ...
Regulation of Sp1 by cell cycle related proteins
Sp1 transcription factor regulates the expression of multiple genes, including the Sp1 gene itself. We analyzed the ability of different cell cycle regulatory proteins to interact with Sp1 and to affect Sp1 promoter activity. ...
Chemical Composition and Cytoprotective Activities of Methanolic Extract of Asplenium adiantum-nigrum L. (Aspleniaceae)
Ferns can be a source of polyphenolic compounds, with the fronds being the main parts described in ethnopharmacological studies. The present study screened polyphenolic phytochemicals and evaluated in vitro activities ...
Un cas clínic sobre el consum de risc d'alcohol com a eina d'integració de coneixements en el Grau de Farmàcia
Podeu consultar la versió castellana al camp recurs relacionat.
Suppressing farnesyl diphosphate synthase alters chloroplast development and triggers sterol-dependent induction of jasmonate- and Fe-related responses
Farnesyl diphosphate synthase (FPS) catalyzes the synthesis of farnesyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate. Arabidopsis (Arabidopsis thaliana) contains two genes (FPS1 and FPS2) encoding ...
Metformin counteracts glucose-dependent lipogenesis and impairs transdeamination in the liver of gilthead sea bream (Sparus aurata)
Metformin is an anti-diabetic drug with a major impact on regulating blood glucose levels by decreasing hepatic gluconeogenesis but also affecting other pathways, including glucose transport and energy/lipid metabolism. ...
Theobromine is responsible for the effects of cocoa on the antibody immune status of rats
Background: A 10% cocoa-enriched diet influences immune system functionality including the prevention of the antibody response and the induction of lower immunoglobulin (Ig) concentrations. However, neither cocoa polyphenols ...
Hesperidin Effects on Gut Microbiota and Gut-Associated Lymphoid Tissue in Healthy Rats
Hesperidin, found in citrus fruits, has shown a wide range of biological properties. Nonetheless, a more in-depth investigation is required on the effects on the immune system, and in particular, on the gut-associated ...
Cyperus esculentus L. Tubers (Tiger Nuts) Protect Epithelial Barrier Function in Caco-2 Cells Infected by Salmonella Enteritidis and Promote Lactobacillus plantarum Growth
Cyperus esculentus L. tubers (tiger nuts) contain different compounds with several intestinal health-promoting properties. Here, we studied the capacity of tiger nuts from Valencia, Spain, to prevent epithelial barrier ...
Bayesian Meta-Analysis: Impacts of Eating Habits and Habitats on Omega-3 Long-Chain Polyunsaturated Fatty Acid Composition and Growth in Cultured Fish
Omega-3 long-chain polyunsaturated fatty acids (<em>n</em>-3 LC-PUFAs) such as eicosapentaenoic acid (20:5<em>n</em>-3, EPA) and docosahexaenoic acid (22:6<em>n</em>-3, DHA) offer protective benefits against various ...
TGF-β2, EGF, and FGF21 Growth Factors Present in Breast Milk Promote Mesenteric Lymph Node Lymphocytes Maturation in Suckling Rats
Breast milk, due to its large number of nutrients and bioactive factors, contributes to optimal development and immune maturation in early life. In this study, we aimed to assess the influence of some growth factors present ...
A diet enriched with cocoa prevents IgE synthesis in a rat allergy model
Previous studies in young rats reported the impact of cocoa intake on healthy immune status and allow suggesting it may have a role in the prevention of some immune-mediated diseases. The aim of this study was to ascertain ...
Carnitine palmitoyltransferase 1C: from Cognition to Cancer
Carnitine palmitoyltransferase 1 (CPT1) C was the last member of the CPT1 family of genes to be discovered. CPT1A and CPT1B were identified as the gate-keeper enzymes for the entry of long-chain fatty acids (as carnitine ...
Dietary Options for Rodents in the Study of Obesity
Abstract: Obesity and its associated metabolic diseases are currently a priority research area. The increase in global prevalence at different ages is having an enormous economic and health impact. Genetic and environmental ...
2-Hydroxy-(4-methylseleno)butanoic acid is used by intestinal Caco-2 Cells as a source of selenium and protects against oxidative stress
<p>Background: Selenium (Se) participates in different functions in humans and other animals through its incorporation</p><p>into selenoproteins as selenocysteine. Inadequate dietary Se is considered a risk factor for ...
Influenza syndromic surveillance based on sentinel pharmacies in Catalonia (Spain) in 2017-2020
Objective: To analyse influenza surveillance data obtained from sentinel pharmacies of Catalonia, Spain, in 2017−18, 2018−19 and 2019-20 influenza seasons. Methods: Influenza surveillance information was collected from a ...
