Bioquímica i Fisiologia: Envíos recientes
Mostrando ítems 61-80 de 634
Alcoholisme: un cas clínic d'abordatge multidisciplinar a la Facultat de Farmàcia
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
Metallomic and Untargeted Metabolomic Signatures of Human Milk from SARS-CoV-2 Positive Mothers
Scope: Lack of information about the impact of maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the elemental and metabolomic profile of human milk (HM). Methods and results: An observational ...
Effect of cocoa-enriched diets on lymphocytes involved in adjuvant arthritis in rats
Cocoa and its flavonoids have potential anti-inflammatory properties in vitro and in acute inflammation models in vivo. The aim of the present study was to ascertain the effects of two cocoa-enriched diets on adjuvant ...
Melanogenesis and hypopigmentation: the case of vitiligo
Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes. Melanin is a complex pigment that provides colour and ...
CD4 expression decrease by antisense oligonucleotides. Inhibition of rat T CD4+ cell reactivity
In previous studies, we have demonstrated the inhibition of CD4 expression in rat lymphocytes treated with phorbol myristate acetate (PMA) by antisense oligonucleotides (AS-ODNs) directed against the AUG start region of ...
Polypurine Reverse-Hoogsteen Hairpins as a Tool for Exon Skipping at the Genomic Level in Mammalian Cells
Therapeutic strategies for rare diseases based on exon skipping are aimed at mediating the elimination of mutated exons and restoring the reading frame of the affected protein. We explored the capability of polypurine ...
Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts
The circadian clock regulates metabolic homeostasis and its disruption predisposes to obesity and other metabolic diseases. However, the effect of phase shifts on metabolism is not completely understood. We examined whether ...
New approaches targeting brown adipose tissue transplantation as a therapy in obesity
Brown adipose tissue (BAT) is raising high expectations as a potential target in the fight against metabolic disorders such as obesity and type 2 diabetes. BAT utilizes fuels such as fatty acids to maintain body temperature ...
Liquid chromatography-tandem mass spectrometry analysis of eicosanoids and related compounds in cell models
Enzyme- and free radical-catalyzed oxidation of polyunsaturated fatty acids (PUFAs) produces the eicosanoids, docosanoids and octadecanoids. This large family of potent bioactive lipids is involved in many biochemical and ...
Mouse brain contains age-dependent extraparenchymal granular structures and astrocytes, both reactive to natural IgM antibodies, linked to the fissura magna
<p>Mouse brains can contain specific polyglucosan aggregates known as Periodic Acid-Schiff (PAS)-granules. Generated in astrocytes, these granules increase with age and exhibit neo-epitopes of carbohydrate nature that are ...
Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in gabaergic neurons of the direct striatal pathway
Home Current Issue Papers in Press Editors' Picks Minireviews Institution: Biblioteca de la Universitat de Barcelona Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in ...
Membrane Vesicles from the Gut Microbiota and Their Interactions with the Host
Gut microbiota plays an essential role in maintaining intestinal homeostasis and human health. Microbiota establishes a complex network of dynamic and reciprocal interactions with the intestinal epithelium and immune system. ...
Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it is not known whether ...
New perspectives on corpora amylacea in the human brain
Corpora amylacea are structures of unknown origin and function that appear with age in human brains and are profuse in selected brain areas in several neurodegenerative conditions. They are constituted of glucose polymers ...
Valoració del primer curs d'implantació de l'assignatura TFG al grau de Farmàcia (UB)
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays
BACKGROUND: MicroRNAs are small non-coding RNAs involved in gene expression regulation by targeting specific regions in the 3[prime]-UTR of the mRNA of their target genes. This binding leads to a decrease in the protein ...
Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients
A long non-coding RNA called ANRIL located on chromosome 9p21.3 has been identified as a novel genetic factor associated with cardiovascular disease. Investigation of several single nucleotide polymorphisms (SNPs) of ...
The role of epigenetics in the development of obesity
The epidemic of obesity has become pandemic, putting a significant burden on the world's healthcare system. While the heritability of the disease is high, all the identified genetic variants associated to obesity account ...
Study of Melatonin as Preventive Agent of Gastrointestinal Damage Induced by Sodium Diclofenac
: Safety profile of nonsteroidal anti‐inflammatory drugs (NSAIDs) has been widely studied and both therapeutic and side effects at the gastric and cardiovascular level have been generally associated with the inhibitory ...
Recent advances in pharmaceutical sciences V
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
