Bioquímica i Fisiologia: Recent submissions
Now showing items 261-280 of 634
Apolipoprotein AV: Gene expression, physiological role in lipid metabolism and clinical relevance
The apolipoprotein APOA5 gene, a member of the gene cluster on chromosome 11q23 that includes APOA1, APOC3 and APOA4, has gained considerable interest as it encodes ApoAV, a key determinant of circulating levels of potentially ...
The hepatocyte nuclear factor 4 (HNF-4) represses the mitochondrial HMG-CoA synthase gene
We have recently shown that the gene for the mitochondrial HMG-CoA synthase is a target for PPAR and that this receptor mediates the induction of this gene by fatty acids. With the aim of gaining further insight into the ...
Effect of PEGylation on Ligand-Targeted Magnetoliposomes: A Missed Goal
We tested the targeting efficiency of magnetoliposomes (MLPs) labeled with tripeptide arginine-glycine-aspartic acid (RGD) on two types of cells: HeLa cells expressing RGD receptors and 3T3 cells lacking RGD receptors. The ...
Alternative Methods to Animal Testing for the Safety Evaluation of Cosmetic Ingredients: An Overview
The safety of cosmetics sold in Europe is based on the safety evaluation of each individual ingredient conducted by those responsible for putting the product on the market. However, those substances for which some concern ...
Central regulation of brown fat thermogenesis in response to saturated or unsaturated long-chain fatty acids
Sensing of long-chain fatty acids (LCFA) in the hypothalamus modulates energy balance, and its disruption leads to obesity. To date, the effects of saturated or unsaturated LCFA on hypothalamic-brown adipose tissue (BAT) ...
Therapeutic applications of essential oils from native and cultivated ecuadorian plants: Cutaneous candidiasis and dermal anti-inflammatory activity
Abstract: Essential oils are a complex mixture of aromatic substances whose pharmacological actions, including antimicrobial, antioxidant, anticancer, and anti-inflammatory activities, have been widely reported. This study ...
Protective Effect of Hesperidin on the Oxidative Stress Induced by an Exhausting Exercise in Intensively Trained Rats
Intensive exercise can lead to oxidative stress, which can be particularly deleterious for lymphoid tissues. Hesperidin has demonstrated its antioxidant activity, but few studies focus on its influence on intensive training. ...
Impact of starvation on digestive enzymes activities and plasma metabolites in Siberian sturgeon (Acipenser baerii, Brandt, 1869)
To increase the current knowledge about the relationship between nutritional status and the digestive capacity of Siberian sturgeon (Acipenser baerii), we addressed the effect of starvation-refeeding and macronutrient ...
Pharmacokinetics of Hydroxytyrosol and Its Sulfate and Glucuronide Metabolites after the Oral Administration of Table Olives to Sprague-Dawley Rats
The pharmacokinetics (PK) of hydroxytyrosol and its metabolites were characterized following oral administration to Sprague-Dawley rats of 3.85 and 7.70 g of destoned Arbequina table olives/kg. Plasma samples were analyzed ...
Sexual Dimorphism Has Low Impact on the Response against Rotavirus Infection in Suckling Rats
Rotaviruses (RVs) are the leading pathogens causing severe and acute diarrhea in children and animals. It is well known that sex contributes to shaping immune responses, thus it could also influence the incidence and ...
Novel In Silico Strategies to Model the In Vivo Nerve Scarring Around Implanted Parylene C Devices
<span style="color:rgb( 34 , 34 , 34 )">The implantation of materials into in vivo peripheral nerves triggers the production of scar tissue. A scar capsule progressively incorporates foreign bodies, which become insulated ...
Transcriptomic microRNA Profiling of Dendritic Cells in Response to Gut Microbiota-Secreted Vesicles
The interconnection between nutrients, metabolites and microbes is a key factor governing the healthy/pathological status of an individual. Thus, microbiota-based research is essential in order to better understand human ...
Rat Mucosal Immunity following an Intensive Chronic Training and an Exhausting Exercise: Effect of Hesperidin Supplementation
immune disruptors leading to transitory immunodepression status, which can be accompanied by alterations of the gastrointestinal functions. Hesperidin intake has demonstrated ergogenic activity and is able to influence the ...
Glyceraldehyde-3-phosphate dehydrogenase is required for efficient repair of cytotoxic DNA lesions in Escherichia coli
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional protein with diverse biological functions in human cells. In bacteria, moonlighting GAPDH functions have only been described for the secreted protein ...
Psoriasi: Fisiopatologia i aplicació de la nanotecnologia al tractament
Psoriasis is an autoimmune inflammatory skin disease characterized by the hyperproliferation of keratinocytes and anomalous keratinization, which generates white plaques. Currently, there is no cure for psoriasis, however, ...
Association between Exercise-Induced Changes in Cardiorespiratory Fitness and Adiposity among Overweight and Obese Youth: A Meta-Analysis and Meta-Regression Analysis
The aim of this study was to determine the minimum change in cardiorespiratory fitness (CRF) required to reduce adiposity (percent body fat) in exercise programs for overweight and obese youth. Studies were identified ...
Creació i aplicació del programa HISTOFLASH a les classes pràctiques d'histologia de l'assignatura Fisiologia i Fisiopatologia III del Grau de Farmàcia de la Universitat de Barcelona. Programa interactiu com a eina d'aprenentatge
Els estudiants de Fisiologia i Fisiopatologia III del Grau de Farmàcia realitzen pràctiques de laboratori entre d'altres activitats complementàries. Una de les pràctiques es basa en l'observació i identificació de teixits ...
Polypodium vulgare L. (Polypodiaceae) as a Source of Bioactive Compounds: Polyphenolic Profile, Cytotoxicity and Cytoprotective Properties in Different Cell Lines.
Pteridophytes, represented by ferns and allies, are an important phytogenetic bridge between lower and higher plants. Ferns have evolved independently of any other species in the plant kingdom being its secondary metabolism ...
El paper del farmacèutic comunitari davant l'incompliment farmacològic del pacient
L'èxit d'una teràpia farmacològica el determinen principalment quatre factors: reconeixement de l'existència de la malaltia, diagnòstic correcte, prescripció adequada i compliment del tractament per part del pacient. ...
Loss of intestinal epithelial barrier function in Salmonella Enteritidis infection
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/63704
