Bioquímica i Fisiologia: Enviaments recents
Ara mostrant els elements 61-80 de 634
Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in gabaergic neurons of the direct striatal pathway
Home Current Issue Papers in Press Editors' Picks Minireviews Institution: Biblioteca de la Universitat de Barcelona Dopamine D1-histamine H3 receptor heteromers provide a selective link to the map-kinase signalling in ...
Membrane Vesicles from the Gut Microbiota and Their Interactions with the Host
Gut microbiota plays an essential role in maintaining intestinal homeostasis and human health. Microbiota establishes a complex network of dynamic and reciprocal interactions with the intestinal epithelium and immune system. ...
Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it is not known whether ...
New perspectives on corpora amylacea in the human brain
Corpora amylacea are structures of unknown origin and function that appear with age in human brains and are profuse in selected brain areas in several neurodegenerative conditions. They are constituted of glucose polymers ...
Valoració del primer curs d'implantació de l'assignatura TFG al grau de Farmàcia (UB)
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays
BACKGROUND: MicroRNAs are small non-coding RNAs involved in gene expression regulation by targeting specific regions in the 3[prime]-UTR of the mRNA of their target genes. This binding leads to a decrease in the protein ...
The role of epigenetics in the development of obesity
The epidemic of obesity has become pandemic, putting a significant burden on the world's healthcare system. While the heritability of the disease is high, all the identified genetic variants associated to obesity account ...
Study of Melatonin as Preventive Agent of Gastrointestinal Damage Induced by Sodium Diclofenac
: Safety profile of nonsteroidal anti‐inflammatory drugs (NSAIDs) has been widely studied and both therapeutic and side effects at the gastric and cardiovascular level have been generally associated with the inhibitory ...
Recent advances in pharmaceutical sciences V
Reproducció del llibre publicat a: http://www.trnres.com/ebookcontents.php?id=249
Comparative sensitivity of tumor and non-tumor cell lines as reliable approach for in vitro cytotoxicity screening of lysine-based surfactants with potential pharmaceutical applications
Surfactants are used as additives in topical pharmaceuticals and drug delivery systems. The biocompatibility of amino acid-based surfactants makes them highly suitable for use in these fields, but tests are needed to ...
Infection of mice by the enteroaggregative E. coli strain 042 and two mutant derivatives overexpressing virulence factors: impact on disease markers, gut microbiota and concentration of SCFAs in feces
Several pathogenic Escherichia coli strains cause diarrhea. Enteroaggregative E. coli (EAEC) strains are one of the diarrheagenic pathotypes. EAEC cells form a “stacked-brick” arrangement over the intestinal epithelial ...
Dietary intake of table olives exerts antihypertensive effects in association with changes in gut microbiota in spontaneously hypertensive rats
Arbequina table olive (AO) consumption lowers blood pressure (BP) in spontaneously hypertensive rats (SHR). This study evaluates whether dietary supplementation with AO induced changes in the gut microbiota that are ...
Implementació d’activitats de caràcter voluntari com a eina de millora de l’aprenentatge en grups d’estudiants nombrosos
Podeu consultar la Setena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/43352
El bonus-test. Una experiència d’avaluació formativa a través del Campus virtual
La Fisiologia Humana és una assignatura comuna dels graus de Nutrició Humana i Dietètica (NHD) i de Ciència i Tecnologia dels Aliments (CTA), que es va posar en marxa el curs 2010-11. Ja des de l’inici vàrem plantejar ...
Effect of pH on L- and D-methionine uptake across the apical membrane of Caco-2 cells
The transport systems involved in intestinal methionine (Met) absorption are described as Na(+)-dependent and Na(+)-independent mechanisms. However, since recent studies have suggested the importance of the H(+) gradient ...
Natural Compounds as Guides for the Discovery of Drugs Targeting G-Protein-Coupled Receptors
G protein-coupled receptors (GPCRs), which constitute the most populous family of the human proteome, are the target of 35-45% of approved therapeutic drugs. This review focuses on natural products (excluding peptides) ...
Multifunctional PLGA nanoparticles combining transferrin-targetability and pH-stimuli sensitivity enhanced doxorubicin intracellular delivery and in vitro antineoplastic activity in MDR tumor cells
Targeted delivery aims to enhance cellular uptake and improve therapeutic outcome with higher disease specificity. The expression of transferrin receptor (TfR) is upregulated on tumor cells, which make the protein Tf and ...
The sigma-1 receptor as key common factor in cocaine and food seeking behaviors
Addiction and eating disorders involve brain reward circuits. A previous history of binge eating predisposes to addictive behavior, while the cessation of exposure to drugs of abuse leads to reward activities, including ...
Cancer immunotherapy using polypurine reverse hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells.
Immunotherapy approaches stand out as innovative strategies to eradicate tumor cells. Among them, PD-1/PD-L1 immunotherapy is considered one of the most successful advances in the history of cancer immunotherapy. We used ...
Osteocalcin signaling in myofibers is necessary and sufficient for optimum adaptation to exercise
Circulating levels of undercarboxylated and bioactive osteocalcin double during aerobic exercise at the time levels of insulin decrease. In contrast, circulating levels of osteocalcin plummet early during adulthood in mice, ...
