Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease 

Tonelli, Michele; Catto, Marco; Sabaté Lagunas, Raimon; Francesconi, Valeria; Laurini, Erik; Pricl, Sabrina; Pisani, Leonardo; Miniero, Daniela Valeria; Liuzzi, Grazia Maria; Gatta, Elena; Relini, Annalisa; Gavín Marín, Rosalina; Río Fernández, José Antonio del; Sparatore, Fabio; Carotti, Angelo (2024-04-16)

A set of twenty-five thioxanthene-9-one and xanthene-9-one derivatives, that were previously shown to inhibit cholinesterases (ChEs) and amyloid β (Aβ40) aggregation, were evaluated for the inhibition of tau protein ...