BCNatal Fetal Medicine Research Center: Envíos recientes
Mostrando ítems 101-120 de 128
Engraftment Potential of Adipose Tissue-Derived Human Mesenchymal Stem Cells After Transplantation in the Fetal Rabbit
Due to their favorable intrinsic features, including engraftment, differentiation, and immunomodulatory potential, adult mesenchymal stem cells (MSCs) have been proposed for therapeutic in utero intervention. Further ...
Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction
Background: genome-wide studies have begun to link subtle variations in both allelic DNA methylation and parent-of-origin genetic effects with early development. Numerous reports have highlighted that the placenta plays a ...
Individual prevention and containment measures in schools in Catalonia, Spain, and community transmission of SARS-CoV-2 after school re-opening
BACKGROUND: Despite their clear lesser vulnerability to COVID-19, the extent by which children are susceptible to getting infected by SARS-CoV-2 and their capacity to transmit the infection to other people remains inadequately ...
Usefulness of circulating microRNAs for the prediction of early preeclampsia at first-trimester of pregnancy
To assess the usefulness of circulating microRNAs (miRNAs) as non-invasive molecular biomarkers for early prediction of preeclampsia, a differential miRNA profiling analysis was performed in first-trimester pooled sera ...
External validation of a non-invasive vaginal tool to assess the risk of intra-amniotic inflammation in pregnant women with preterm labor and intact membranes
Objectives: To prospectively validate the diagnostic performance of a non-invasive point-of-care tool (Rapid IAI System), including vaginal alpha-fetoprotein and interleukin-6, to predict the occurrence of intra-amniotic ...
Premature placental aging in term small-for-gestational-age and fetal-growth-restricted fetuses
Objective The aim of this study was to perform a comprehensive assessment of the placental aging process through senescence and apoptotic markers in late-onset small fetuses classified as SGA or FGR. Study Design A prospective ...
Cardiac remodeling from the fetus to adulthood
Prenatal cardiac remodeling refers to in utero changes in the fetal heart that occur as a response to an adverse intrauterine environment. In this article, we will review the main mechanisms leading to cardiac remodeling ...
SARS-CoV-2 RNA and antibody detection in human milk from a prospective multicenter study in Spain
Objectives To develop and validate a specific protocol for SARS-CoV-2 detection in breast milk matrix and to determine the impact of maternal SARS-CoV-2 infection on the presence, concentration and persistence of specific ...
Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism; intervention; and long-term consequences.
Background Intrauterine growth restriction is associated with an increased future risk for developing cardiovascular diseases. Hypoxia in utero is a common clinical cause of fetal growth restriction. We have previously ...
Maternal proteomic profiling reveals alterations in lipid metabolism in late-onset fetal growth restriction
Fetal growth restriction defined as the failure to achieve the fetal genetic growth potential is a major cause of perinatal morbidity and mortality. The role of maternal adaptations to placental insufficiency in this ...
Nomograms of Fetal Cardiac Dimensions at 18-41 Weeks of Gestation
OBJECTIVE: There is a need for standardized reference values for cardiac dimensions in prenatal life. The objective of the present study was to construct nomograms for fetal cardiac dimensions using a well-defined ...
Neonatal Neurobehavior and Diffusion MRI Changes in Brain Reorganization Due to Intrauterine Growth Restriction in a Rabbit Model
Background: Intrauterine growth restriction (IUGR) affects 5-10% of all newborns and is associated with a high risk of abnormal neurodevelopment. The timing and patterns of brain reorganization underlying IUGR are poorly ...
MRI at 12 ± 2 months' corrected age without sedation
(Letter to the Editor) Sir, We read with interest the article by Edwards and Arthurs [1] about the methodological challenges of acquiring highquality MRI in young children. Although the use of anaesthesia and sedation is ...
Evaluación de una intervención mediante sofrología para disminuir la ansiedad en las gestantes con un feto con retraso de crecimiento
Objetivo: comparar el grado de ansiedad de un grupo de mujeres con un feto con retraso de crecimiento intrauterino (RCIU) visitadas exclusivamente por especialistas en medicina maternofetal en relación a otras mujeres que, ...
La influencia del estrés o ansiedad de la gestante en el peso fetal o neonatal: revisión bibliográfica
Objetivo: examinar si la presencia de ansiedad o estrés materno durante el embarazo influye en el peso del feto o el neonato y cómo cambian las variables asociadas. Metodología: Se llevó a cabo una revisión bibliográfica ...
Cardiac and placental mitochondrial characterization in a rabbit model of intrauterine growth restriction
BACKGROUND: Intrauterine growth restriction (IUGR) is associated with cardiovascular remodeling persisting into adulthood. Mitochondrial bioenergetics, essential for embryonic development and cardiovascular function, are ...
Mitochondrial toxicity and caspase activation in HIV pregnant women.
To assess the impact of HIV-infection and highly active anti-retroviral treatment in mitochondria and apoptotic activation of caspases during pregnancy and their association with adverse perinatal outcome. Changes of ...
The Interplay between Pathophysiological Pathways in Early-Onset Severe Preeclampsia Unveiled by Metabolomics
Introduction: Preeclampsia is a multi-system disorder unique to pregnancy responsible for a great part of maternal and perinatal morbidity and mortality. The precise pathogenesis of this complex disorder is still unrevealed. ...
Reliability and Concurrent and Construct Validity of a Food Frequency Questionnaire for Pregnant Women at High Risk to Develop Fetal Growth Restriction
Accuracy of dietary assessment instruments such as food frequency questionnaire (FFQ) is crucial in the evaluation of diet-disease relationships. Test-retest reliability and concurrent and construct validity of a FFQ were ...
Autophagy is Involved in Cardiac Remodeling in Response to Environmental Temperature Change
Objectives: To study the reversibility of cold-induced cardiac hypertrophy and the role of autophagy in this process. Background: Chronic exposure to cold is known to cause cardiac hypertrophy independent of blood pressure ...
