Recent submissions

Analysis of cell free DNA to predict outcome to bevacizumab therapy in colorectal cancer patients

Venken, Tom; Miller, Ian; Arijs, Ingrid; Thomas, Valentina; Barat, Ana; Betge, Johannes; Serna, Garazi; Nuciforo, Paolo (Publication date: 2024-06-03)

Cell free DNA; Bevacizumab; Colorectal cancer

Patient-reported outcomes and tolerability in patients receiving ripretinib versus sunitinib after treatment with imatinib in INTRIGUE, a phase 3, open-label study

Gelderblom, Hans; Jones, Robin; Blay, Jean-Yves; George, Suzanne; von Mehren, Margaret; Zalcberg, John; Serrano, Cesar (Publication date: 2023-08-31)

Gastrointestinal stromal tumours; Patient reported outcome measures; Protein kinase inhibitors

The Medical Oncology resident mentor: situation and workload

Elez Fernandez, Mª Elena; Quintanar, T.; Bosch-Barrera, J; Corral, J.; Lainez, N.; Moreno, Victor (Publication date: 2021-03-11)

Oncologia mèdica; Mentor resident; Càrrega de treball

First-in-human, dose-escalation, phase 1 study of anti-angiopoietin-2 LY3127804 as monotherapy and in combination with ramucirumab in patients with advanced solid tumours

Martín Liberal, Juan Jesús; Jungels, Christiane; Martin-Romano, Patricia; Rodon Ahnert, Jordi; Aftimos, Philippe; Hollebecque, Antoine (Publication date: 2021-11-11)

Desenvolupament de fàrmacs

Short-course radiotherapy for rectal cancer: real-world evidence in Argentina

Freile, Berenice; Galli, Mariana; Sanchez Loria, Fernando; Tissera, Natalia Soledad; Waisberg, Federico; Esteso, Federico (Publication date: 2023-09-20)

Latin America; Rectal cancer; Short-course radiotherapy

Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

CASSIER, Philippe; Gomez-Roca, Carlos; Korakis, Iphigenie; Champiat, Stephane; GARRALDA, Elena; Galvao, Vladimir (Publication date: 2025-04-25)

Anti-tumor efficacy; Pembrolizumab combination; Solid tumors

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane

Hastie, Kathryn; Li, Zhe; Ke, Zunlong; Halfmann, Peter; DeWald, Lisa Evans; McArdle, Sara; Grinyo i Escuer, Ariadna (Publication date: 2025-04-08)

Ebola virus; Virion membrane

Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group

Mosele, Maria; Stenzinger, Albrecht; Bayle, Arnaud; Bieche, Ivan; Westphalen, Benedikt; Barlesi, Fabrice; Dienstmann, Rodrigo; Serrano, Cesar; Mateo, Joaquin (Publication date: 2024-06-27)

Advanced cancer; Next-generation sequencing; Precision medicine

Genetic immune escape landscape in primary and metastatic cancer

Martínez-Jiménez, Francisco; Priestley, Peter; Shale, Charles; Baber, Jonathan; Rozemuller, Erik; Cuppen, Edwin (Publication date: 2023-07-04)

Genome; Tumour immunology

Mirvetuximab soravtansine in folate receptor alpha (FRα)–high platinum-resistant ovarian cancer: final overall survival and post hoc sequence of therapy subgroup results from the SORAYA trial

Coleman, Robert; Cecere, Sabrina Chiara; Lorusso, Domenica; OAKNIN, ANA; denys, hannelore; Colombo, Nicoletta (Publication date: 2024-10-04)

Ovarian Cancer

Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors

Alouani, Emily; Sinicrope, Frank; Decraecker, Marie; Ros Codoñer, Javier; taieb, julien; Ambrosini, Margherita; Lonardi, Sara (Publication date: 2025-03-21)

Colorectal cancer; Immune checkpoint inhibitor; Microsatellite

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Sandström Gerdtsson, Anna; Knulst, Mattis; Botling, Johan; Mezheyeuski, Artur; Micke, Patrick; Ek, Sara (Publication date: 2023-05-10)

Immune infiltration; Spatial omics; Tertiary lymphoid structures

First-in-Human Phase I Study of a CD16A Bispecific Innate Cell Engager, AFM24, Targeting EGFR-Expressing Solid Tumors

El-Khoueiry, Anthony; Thomas, Jacob; Livings, Claire; Hintzen, Gabriele; Saavedra, Omar; GARRALDA, Elena (Publication date: 2025-04-22)

Bispecific innate cell engager; Solid tumors

MODUL cohort 2: an adaptable, randomized, signal-seeking trial of fluoropyrimidine plus bevacizumab with or without atezolizumab maintenance therapy for BRAFwt metastatic colorectal cancer

Tabernero Caturla, Josep; Grothey, Axel; Arnold, Dirk; Ducreux, M.; O’Dwyer, P.; de Gramont, Aimery (Publication date: 2022-10-27)

Atezolizumab; Bevacizumab; Metastatic colorectal cancer

PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis

Sanz, Maria; Ruiz-Torres, Miguel; Aguirre-Portolés, Cristina; El Bakkali, Aicha; Salvador-Barbero, Beatriz; Villarroya-Beltri, Carolina; Malumbres, Marcos (Publication date: 2024-07-19)

Chromosome clustering; Mitosis; Phosphatase

Digital Microscopy Augmented by Artificial Intelligence to Interpret Bone Marrow Samples for Hematological Diseases

Bermejo-Pelaez, David; Rueda Charro, Sandra; García Roa, María; Trelles-Martinez, Roberto-Oswaldo; Bobes-Fernández, Alejandro; Hidalgo Soto, Marta (Publication date: 2024-03-11)

Artificial intelligence; Bone marrow aspirates; Digital microscopy

Syndecan-3 positively regulates the pro-inflammatory function of macrophages

Lee, So Young; Prieto-Fernández, Endika; Antoñana Vildosola, Asier; Velasco-Beltrán, Paloma; Bosch Martinez, Alexandre; Egia-Mendikute, Leire (Publication date: 2025-07-02)

Angiogenesis; Cancer; Syndecans

AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors

Dunn, Shanade; Eberlein, Cath; Yu, Jason; Ong, Swee Hoe; Yelland, Urs; Serra Elizalde, Violeta; Gris Oliver, Albert (Publication date: 2022-12-20)

Cancer therapeutic resistance; Target identification

An observational, multicentre study of cabazitaxel in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (CAPRISTANA)

Carles Galceran, Joan; Pichler, Angelika; Korunkova, Hana; Tomova, Antoaneta; Ghosn, Marwan; El Karak, Fadi (Publication date: 2021-03-11)

Càncer de pròstata resistent a la castració metastàsica; Cabazitaxel; Qualitat de vida relacionada amb la salut

Independent transcriptional patterns reveal biological processes associated with disease-free survival in early colorectal cancer

Knapen, Daan; Hone Lopez, Sara; de Groot, Derk Jan; de Haan, Jacco; de Vries, Elisabeth; Dienstmann, Rodrigo (Publication date: 2024-05-09)

Patrons transcripcionals; Supervivència; Càncer colorectal precoz

Articles científics - VHIO: Recent submissions

Analysis of cell free DNA to predict outcome to bevacizumab therapy in colorectal cancer patients ﻿

Patient-reported outcomes and tolerability in patients receiving ripretinib versus sunitinib after treatment with imatinib in INTRIGUE, a phase 3, open-label study ﻿

The Medical Oncology resident mentor: situation and workload ﻿

First-in-human, dose-escalation, phase 1 study of anti-angiopoietin-2 LY3127804 as monotherapy and in combination with ramucirumab in patients with advanced solid tumours ﻿

Short-course radiotherapy for rectal cancer: real-world evidence in Argentina ﻿

Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers ﻿

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane ﻿

Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group ﻿

Genetic immune escape landscape in primary and metastatic cancer ﻿

Mirvetuximab soravtansine in folate receptor alpha (FRα)–high platinum-resistant ovarian cancer: final overall survival and post hoc sequence of therapy subgroup results from the SORAYA trial ﻿

Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors ﻿

Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer ﻿

First-in-Human Phase I Study of a CD16A Bispecific Innate Cell Engager, AFM24, Targeting EGFR-Expressing Solid Tumors ﻿

MODUL cohort 2: an adaptable, randomized, signal-seeking trial of fluoropyrimidine plus bevacizumab with or without atezolizumab maintenance therapy for BRAFwt metastatic colorectal cancer ﻿

PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis ﻿

Digital Microscopy Augmented by Artificial Intelligence to Interpret Bone Marrow Samples for Hematological Diseases ﻿

Syndecan-3 positively regulates the pro-inflammatory function of macrophages ﻿

AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors ﻿

An observational, multicentre study of cabazitaxel in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (CAPRISTANA) ﻿

Independent transcriptional patterns reveal biological processes associated with disease-free survival in early colorectal cancer ﻿