Recent submissions

The combination of avutometinib and defactinib in treating recurrent low-grade serous ovarian cancer: a plain language summary of the Phase II clinical trial ENGOT-OV60/GOG-3052/RAMP 201

Banerjee, Susana; Clamp, Andrew; Van Nieuwenhuysen, Els; Aghajanian, Carol; D'Hondt, Veronique; Monk, Bradley; OAKNIN, ANA (Publication date: 2026-03-25)

Avutometinib; Defactinib; Plain language summary

Second-event endpoints (EFS2, PRFS2 and PFS2) after anti-PD-(L)1-based RCTs: a systematic review and meta-analysis

Martín Quesada, Ana Isabel; Trapani, Dario; Jiménez-Labaig, Pablo; Mirallas, Oriol; Rullán, Antonio José; Amaral, Teresa; FELIP, ENRIQUETA; Tabernero, Josep (Publication date: 2026-03-25)

Immune checkpoint inhibitor; Immunotherapy; Solid tumor

Efficacy and Safety of Glofitamab Plus Polatuzumab Vedotin in Relapsed/Refractory Large B-Cell Lymphoma Including High-Grade B-Cell Lymphoma: Results From a Phase Ib/II Trial

Bosch, Francesc; Larsen, Thomas Stauffer; Avigdor, Abraham; Hutchings, Martin; Sureda, Anna; Corradini, Paolo (Publication date: 2026-03-25)

Eficacia y seguridad; Linfoma de células B grandes; Recaída

New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis

García Domínguez, José M.; VILLARRUBIA, NOELIA; Montalban, Xavier; Rodero-Romero, Alexander; Dominguez-Mozo, Maria Inmaculada; Monreal, Enric; Fernández Velasco, José Ignacio; Comabella Lopez, Manuel (Publication date: 2026-03-25)

Serum soluble factors; Inflammatory disability; Multiple sclerosis

Granulomonocytapheresis for chronic inflammatory diseases and sepsis

Okada, Hideshi; Miki, Takahiro; Mineshima, Michio; Iba, Toshiaki; Ferrer, Ricard (Publication date: 2026-03-25)

Cytokine; Granulocyte; Hemofiltration

UpSMART: five years of digital innovation in cancer clinical research—achievements, challenges, and recommendations

O'Regan, Paul; Butt, Fouziah; Carter, Louise; Graham, Donna M.; Le Blanc, Anja; Hoskins, Richard; Pretelli, Giulia; GARRALDA, Elena (Publication date: 2026-03-25)

Cancer clinical trials; Clinical trial innovation; Digital health technologies

Change in Antinuclear Antibodies After Lung Transplantation in Patients with Systemic Sclerosis

Barreales, Victor; Fernández Luque, Alejandra; Viñas-Gimenez, Laura; Triginer Gil, Laura; Simeón-Aznar , Carmen Pilar; Guillen-Del-Castillo, Alfredo; Berastegui Garcia, Cristina; Meseguer, Anna; Monforte, Victor; Saez-Gimenez, Berta; Villar, Ana; Ojanguren, Iñigo; Codina, Claudia; Sanz Martínez, María Teresa; Perurena-Prieto, Janire; Alcalá-González, Luis Gerardo; Bravo Masgoret, Carles (Publication date: 2026-03-25)

Antinuclear antibodies; Autoantibodies; Lung transplantation

Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

Tyrer, Jonathan; Dennis, Joe; Leslie, Goska; Bolla, Manjeet; Lush, Michael; Barnes, Daniel; Balmaña, Judith (Publication date: 2026-03-25)

Genome-wide association study; Serous ovarian cancer

Combination therapy overcomes secondary PARPi resistance in ATM-deficient prostate cancer

Arce Gallego, Sara; Esquefa, Victor; Domènech Garcia, Heura; Aguilar Villalba, Daniel; Casals, Teresa; Oliveira Tercero, Anna; de Llobet Cucalón, Lara; Anselmino, Nicolás; Herranz, Nicolas; Salca, Andrei; Mir Arnau, Gisela; Simonetti, Sara; Brandariz, Julian; Casanova-Salas, Irene; Serra, Violeta; Mateo, Joaquin (Publication date: 2026-03-25)

Combination therapy; PARPi inhibitors; Prostate cancer

Navigating the Lung Transplantation Journey: A Qualitative Study of the Caregivers’ Experiences and Needs

González-Álvarez, Melissa; Megido, María Jesús; PEDREIRA-ROBLES, GUILLERMO; Escrig-Pinol, Astrid; Escobar Fornieles, Roser; Fabrellas, Nuria (Publication date: 2026-03-25)

Caregiver; Communication; Experiences

Pulmonary arterial hypertension associated with exposure to toxic rapeseed oil

Cruz Utrilla, Alejandro; Cantero Acedo, Álvaro; Tenes Mayén, José Andrés; Enguita, Ana Belén; Delgado Jiménez, Juan Francisco; López Meseguer, Manuel (Publication date: 2026-03-23)

Pulmonary arterial hypertension; Toxic rapeseed oil

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors

PRIEGO, ARACELI; Rojas Laimito, Katerin; lord, simon; Goetze, Thorsten; Cortes, Javier; GARRALDA, Elena (Publication date: 2026-03-23)

Monoclonal antibody; Solid tumors; HER2 positive

Migraine management during pregnancy, breastfeeding and in women planning pregnancy

Sandoe, Claire; Iannone, Luigi Francesco; Pelzer, Nadine; Ornello, Raffaele; Maassen van den Brink, Antoinette; Puledda, Francesca; Gómez Dabó, Laura; Pozo-Rosich, Patricia (Publication date: 2026-03-20)

Breastfeeding; Migraine treatment; Pregnancy

A predictive model for early intubation in patients with COVID–19–induced acute hypoxemic respiratory failure under awake prone position

Morales-Quinteros, Luis; Fuentes, Nora; Olmos, Matias Exequiel; Busico, Marina; Vitali, Alejandra; Plata Menchaca, Erika Paola; Muriel, Alfonso; Ferrer, Ricard (Publication date: 2026-03-20)

Acute respiratory distress syndrome; Acute respiratory failure; COVID-19

Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia

Cabrera Serrano, Antonio José; Rodriguez-Sevilla, Juan Jose; Reyes-Zurita, Fernando J.; Collado, Rosa; Puiggros, Anna; Sánchez Maldonado, Jose Manuel; Jerez, Andres (Publication date: 2026-03-20)

Health services and outcomes; Lymphoid neoplasia

Nexobrid Use in the Elderly

Lugilde Guerbek, Alexander; López Martínez, José Antonio; Arteaga, Alex; Grabosky Elbaile, Alejandro; Orois Gómez, Sara; Serracanta Domènech, Jordi; Bulla, Antonio; Rivas-Nicolls, Danilo; Barret Nerín, Joan-Pere (Publication date: 2026-03-20)

Nexobrid; Elderly; Experience

Induction Regimens in High-Risk Neuroblastoma: Systematic Review of Response Rates and Toxicities

Martin, Samantha; Robinson, Eva; Weller, Edie; Bagatell, Rochelle; Moreno, Lucas; DuBois, Steven (Publication date: 2026-03-20)

Neuroblastoma: Toxicity

Streptozotocin plus 5-fluorouracil followed by everolimus or the reverse sequence in patients with advanced pancreatic neuroendocrine tumors (SEQTOR-GETNE phase III study): a randomized clinical trial

tafuto, salvatore; Krogh, Merete; Klümpen, Heinz-Josef; Capdevila Castillon, Jaume; Teule, Alex; Garcia-Carbonero, Rocio (Publication date: 2026-03-20)

5-fluorouracil; Advanced pancreatic neuroendocrine neoplasm; Everolimu

PD-L1 and the risk of bacterial infection in patients with chronic liver diseases: An international multicohort study

Juanola Mayos, Adrià; Mezzano, Gabriel; POSE MENDEZ, ELISA; MORETA, MARIA JOSE; Incicco, Simone; Gagliardi, Roberta; Vargas Blasco, Victor Manuel (Publication date: 2026-03-20)

Bacterial infection; Biomarkers; Decompensated cirrhosis

The Long-Term Outcomes of Corticosteroid Use in COVID-19 Patients with Cardiovascular Disease: A Propensity-Matched Analysis from the Multi-Center International Prospective Registry (HOPE-2)

García-Onrubia, Jorge; Feltes, Gisela; Vazirani Ballesteros, Ravi; Sánchez del Hoyo, Rafael; Viana-Llamas, María C.; RAPOSEIRAS-ROUBIN, SERGIO; Uribarri, Aitor (Publication date: 2026-03-19)

SARS-CoV-2 infection; Corticosteroid therapy; Pre-existing heart disease

Articles científics - HVH: Recent submissions

The combination of avutometinib and defactinib in treating recurrent low-grade serous ovarian cancer: a plain language summary of the Phase II clinical trial ENGOT-OV60/GOG-3052/RAMP 201 ﻿

Second-event endpoints (EFS2, PRFS2 and PFS2) after anti-PD-(L)1-based RCTs: a systematic review and meta-analysis ﻿

Efficacy and Safety of Glofitamab Plus Polatuzumab Vedotin in Relapsed/Refractory Large B-Cell Lymphoma Including High-Grade B-Cell Lymphoma: Results From a Phase Ib/II Trial ﻿

New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis ﻿

Granulomonocytapheresis for chronic inflammatory diseases and sepsis ﻿

UpSMART: five years of digital innovation in cancer clinical research—achievements, challenges, and recommendations ﻿

Change in Antinuclear Antibodies After Lung Transplantation in Patients with Systemic Sclerosis ﻿

Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer ﻿

Combination therapy overcomes secondary PARPi resistance in ATM-deficient prostate cancer ﻿

Navigating the Lung Transplantation Journey: A Qualitative Study of the Caregivers’ Experiences and Needs ﻿

Pulmonary arterial hypertension associated with exposure to toxic rapeseed oil ﻿

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors ﻿

Migraine management during pregnancy, breastfeeding and in women planning pregnancy ﻿

A predictive model for early intubation in patients with COVID–19–induced acute hypoxemic respiratory failure under awake prone position ﻿

Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia ﻿

Nexobrid Use in the Elderly ﻿

Induction Regimens in High-Risk Neuroblastoma: Systematic Review of Response Rates and Toxicities ﻿

Streptozotocin plus 5-fluorouracil followed by everolimus or the reverse sequence in patients with advanced pancreatic neuroendocrine tumors (SEQTOR-GETNE phase III study): a randomized clinical trial ﻿

PD-L1 and the risk of bacterial infection in patients with chronic liver diseases: An international multicohort study ﻿

The Long-Term Outcomes of Corticosteroid Use in COVID-19 Patients with Cardiovascular Disease: A Propensity-Matched Analysis from the Multi-Center International Prospective Registry (HOPE-2) ﻿