Sistema de Salut de Catalunya
Institut Català de la Salut
[O’Regan P, Butt F] Digital Cancer Research Team, CRUK National Biomarker Centre, The University of Manchester, Manchester, United Kingdom. [Carter L, Graham DM] Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom. The Christie NHS Foundation Trust, Manchester, United Kingdom. [Le Blanc A, Hoskins R] Digital Cancer Research Team, CRUK National Biomarker Centre, The University of Manchester, Manchester, United Kingdom. Research IT, The University of Manchester, Manchester, United Kingdom. [Pretelli G, Garralda E] Unitat de Desenvolupament de Fàrmacs en Fase Inicial, Vall d’Hebron Institut d'Oncologia (VHIO), Barcelona, Spain. Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
2026-03-25T09:00:57Z
2026-03-25T09:00:57Z
2025-11-27
Cancer clinical trials; Clinical trial innovation; Digital health technologies
Ensayos clínicos oncológicos; Innovación en ensayos clínicos; Tecnologías de salud digital
Assaigs clínics oncològics; Innovació en assaigs clínics; Tecnologies de salut digital
UpSMART, a research programme involving 24 European cancer centres, aimed to promote digital innovation in early-phase clinical research addressing challenges in recruitment, data collection and analysis. Several open-source digital healthcare products (DHPs) were developed through UpSMART, including eTARGET and trialFinder for trial matching, and PROACT 2.0 for patient-reported data. Lessons learned highlight the importance of multidisciplinary teams, sustainable funding and deployment, and engagement with the research community to maximise impact.
The author(s) declare financial support was received for the research and/or publication of this article. This work was supported by Cancer Research UK (CRUK), Associazione Italiana per la Ricerca sul Cancro (AIRC) and Fundacion Científica-Asociacion Espanola Contra el Cancer (FC-AECC), via an Accelerator Award [A29374] through the CRUK National Biomarker Centre [CTRNBC-2022/100001]. This work was supported by Azure sponsorship credits granted by Microsoft’s AI for Good Research Lab. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication.
Article
Published version
English
Assaigs clínics; Programari; Històries clíniques - Informàtica; Medicina - Innovacions; Oncologia; INFORMATION SCIENCE::Information Science::Computing Methodologies::Software; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Clinical Studies as Topic::Clinical Trials as Topic; DISCIPLINES AND OCCUPATIONS::Health Occupations::Medicine::Internal Medicine::Medical Oncology; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Data Collection::Records::Medical Records::Medical Records Systems, Computerized::Electronic Health Records; CIENCIA DE LA INFORMACIÓN::Ciencias de la información::metodologías computacionales::soporte lógico (informática); TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios clínicos como asunto::ensayos clínicos como asunto; DISCIPLINAS Y OCUPACIONES::profesiones sanitarias::medicina::medicina interna::oncología médica; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::recopilación de datos::registros::registros médicos::sistemas informatizados de historias clínicas
Frontiers Media
Frontiers in Digital Health;7
https://doi.org/10.3389/fdgth.2025.1708067
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
Articles científics - HVH [3437]
