Recent submissions

Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases

Peters, Solange; Trigo, José; Besse, Benjamin; NAVARRO, ALEJANDRO; Moreno, Victor; Olmedo García, María Eugenia (Publication date: 2024-02-09)

Chemotherapy-free interval; Lurbinectedin; Response rate

Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment

Gulley, James; Schlom, Jeffrey; Barcellos-Hoff, Mary Helen; Wang, Xiao-Jing; Seoane, Joan; Audhuy, Francois (Publication date: 2023-05-23)

Immune checkpoint inhibitor; Tumor microenvironment

Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia

Errazquin, Ricardo; Page, Angustias; Suñol, Anna; Segrelles, Carmen; Carrasco Lopez, Estela; Peral, Jorge; Balmaña, Judith (Publication date: 2023-06-06)

Head and neck squamous cell carcinoma; Mouse model; Oral mucosa

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer

Harvey-Jones, Elizabeth J.; Raghunandan, Maya; Robbez-Masson, Luisa; Magraner-Pardo, Lorena; Alaguthurai, Thanu; Yablonovitch, Arielle; Balmaña, Judith; Serra, Violeta (Publication date: 2024-04-12)

PARP inhibitors; Breast cancer; Drug resistance

The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling

Plana-Carmona, Marcos; Stik, Grégoire; Bulteau, Romain; Segura Morales, Carolina; Alcazar Perez, Noelia; Wyatt, Chris; Tian, Tian V; Vila Casadesus, Maria (Publication date: 2022-12-12)

Gene regulation; Somatic cell reprogramming; Trophectoderm

Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer

Yndestad, Synnøve; Engebrethsen, Christina; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun; Llop-Guevara, Alba; Herencia Ropero, Andrea; Serra, Violeta (Publication date: 2024-01-09)

Homologous recombination; Primary breast cancer

AXL – a new player in resistance to HER2 blockade

Cejalvo, Juan Miguel; ADAM-ARTIGUES, ANNA; ARENAS LAHUERTA, ENRIQUE JAVIER; Arribas, Joaquin; Prat, Aleix (Publication date: 2023-11-08)

Cancer; HER2 disease; Resistance

GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis

Sánchez Maldonado, Jose Manuel; Cabrera Serrano, Antonio José; Chattopadhyay, Subhayan; CAMPA, DANIELE; Garrido , María del Pilar; Macauda, Angelica; Jerez, Andres (Publication date: 2023-05-05)

Genetic variants; Multiple myeloma; Obesity

Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 Study

Randon, Giovanni; Nakamura, Yoshiaki; CREMOLINI, CHIARA; Yaeger, Rona; Lonardi, Sara; Elez, Elena; Ros, Javier (Publication date: 2024-02-14)

Hyperselection; Metastatic colorectal cancer

Endocrine and Neuroendocrine Tumors Special Issue—Checkpoint Inhibitors for Adrenocortical Carcinoma and Metastatic Pheochromocytoma and Paraganglioma: Do They Work?

Jimenez, Camilo; Armaiz-Pena, Gustavo; Dahia, Patricia; Lu, Yang; De Almeida Toledo, Rodrigo; Varghese, Jeena; Habra, Mouhammed Amir (Publication date: 2023-01-10)

Adrenocortical cancer; Checkpoint inhibitors; Metastatic paraganglioma

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy

Appierto, Valentina; Silvestri, Marco; Baselga Torres, Jose Manuel; Piccart, Martine; Nuciforo, Paolo Giovanni; Di Cosimo, Serena; Pizzamiglio, Sara (Publication date: 2021-09-01)

Càncer de mama; MicroRNA circulants; Trastuzumab

ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer

Estévez-García, Purificación; Martin Martorell, Paloma; Sais, Elia; Bosch-Barrera, Joaquim; Sabatier, Renaud; Nadal, Ernest; OAKNIN, ANA (Publication date: 2025-04-04)

Advanced squamous non-small cell lung cancer; Autophagy; Chemotherapy

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

van Schooten, Tessa Suzanne; Derks, Sarah; Jiménez-Martí, Elena; Carneiro, Fatima; Ruiz-Garcia, Erika; Alsina, Maria; Molero, Cristina; Figueiredo, Ceu (Publication date: 2023-06-07)

Gastric cancer; Tumor microenvironment; Prevention

MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer

Dinami, Roberto; Pompili, Luca; Petti, Eleonora; Porru, Manuela; D’Angelo, Carmen; Di Vito, Serena; Serra Elizalde, Violeta (Publication date: 2023-04-24)

Target therapy; Telomeres; Triple-negative breast cancer

ESMO Recommendations on clinical reporting of genomic test results for solid cancers

van de Haar, Joris; Roepman, Paul; andre, fabrice; Castro, Elena; Chakravarty, Debyani; Balmaña, Judith; Dienstmann, Rodrigo; Mateo, Joaquin (Publication date: 2024-10-31)

Genomics; Next-generation sequencing; Targeted therapies

Phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination–proficient ovarian cancer

Schab, Angela; Compadre, Amanda; Drexler, Rebecca; loeb, Megan; Rodriguez, Kevin; Brill, Joshua; Serra, Violeta (Publication date: 2025-07-11)

DNA repair; Molecular diagnosis; Oncology

SENSE EPI reconstruction with 2D phase error correction and channel-wise noise removal

Powell, Elizabeth; Schneider, Torben; Battiston, Marco; Toosy, Ahmed; Clayden, Jonathan D.; Gandini Wheeler-Kingshott, Claudia A.M.; Grussu, Francesco (Publication date: 2022-10-06)

Nyquist ghost; Denoising; Diffusion

Evolving and Improving the Sustainability of Molecular Tumor Boards: The Value and Challenges

Bartels, Marius; Chibaudel, Benoist; Dienstmann, Rodrigo; Lehtiö, Janne; Piccolo, Alberta; Michielin, Olivier (Publication date: 2025-02-17)

Molecular tumor board; Molecularly guided therapy; Precision oncology

Machine learning techniques to estimate the degree of binder activity of reclaimed asphalt pavement

Botella, Ramon; Lo Presti, Davide; Vasconcelos, Kamilla; Martínez, Adriana H.; Miró, Rodrigo; Bernatowicz, Kinga (Publication date: 2022-10-18)

Recycling; Machine learning; Artificial neural networks

Bruton tyrosine kinase covalent inhibition shapes the immune microenvironment in chronic lymphocytic leukemia

Medina-Gil, Daniel; Palomo Diaz, Laura; Lázaro, Gonzalo; Martín Mur, Beatriz; Hernández Pascual, Cristina; Castells, Oriol; Sánchez, Belén; Pagès Geli, Carlota; Pujadas, Gemma; Crespo, Marta; Navarro Garces, Victor; Muñoz-Torres, Pau Marc; Cabirta, Alba; Abrisqueta, Pau; Bosch, Francesc (Publication date: 2025-09-02)

Bruton tyrosine kinase covalent inhibition; Immune microenvironment; Chronic lymphocytic leukemia

Sistema de Salut de Catalunya: Recent submissions

Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases ﻿

Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment ﻿

Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia ﻿

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer ﻿

The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling ﻿

Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer ﻿

AXL – a new player in resistance to HER2 blockade ﻿

GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis ﻿

Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 Study ﻿

Endocrine and Neuroendocrine Tumors Special Issue—Checkpoint Inhibitors for Adrenocortical Carcinoma and Metastatic Pheochromocytoma and Paraganglioma: Do They Work? ﻿

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy ﻿

ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer ﻿

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally ﻿

MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer ﻿

ESMO Recommendations on clinical reporting of genomic test results for solid cancers ﻿

Phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination–proficient ovarian cancer ﻿

SENSE EPI reconstruction with 2D phase error correction and channel-wise noise removal ﻿

Evolving and Improving the Sustainability of Molecular Tumor Boards: The Value and Challenges ﻿

Machine learning techniques to estimate the degree of binder activity of reclaimed asphalt pavement ﻿

Bruton tyrosine kinase covalent inhibition shapes the immune microenvironment in chronic lymphocytic leukemia ﻿