Recent submissions

Value of Early Circulating Tumor Cells Dynamics to Estimate Docetaxel Benefit in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients

Lozano, Rebeca; Lorente, David; Aragon, Isabel M.; Romero-Laorden, Nuria; Nombela, Paz; Mateo Valderrama, Joaquim (Publication date: 2022-03-01)

Biomarcadores; Células tumorales circulantes; Docetaxel

RAD51 as a biomarker for homologous recombination deficiency in high-grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test

Kramer, Claire; Yaniz-Galende, Elisa; Pellegrino, Benedetta; ter Haar, Natalja; Llop-Guevara, Alba; Herencia Ropero, Andrea; Serra, Violeta (Publication date: 2023-10-16)

Biomarker; High-hrade serous ovarian carcinoma; Homologous recombination deficiency

Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

Martínez Martín, Sandra; Castillo Cano, Virginia; Massó Vallés, Daniel; López-Estévez, Sergio; Thabussot, Hugo; Beaulieu, Marie-Eve; Soucek, Laura; Foradada Felip, Laia; Kaur, Jastrinjan; Serrano del Pozo, Erika (Publication date: 2023-03-16)

Omomyc; Mass spectrometry; Protein therapeutics

Predictive Role of CD36 Expression in HER2-Positive Breast Cancer Patients Receiving Neoadjuvant Trastuzumab

Ligorio, Francesca; Di Cosimo, Serena; verderio, paolo; ciniselli, chiara maura; Pizzamiglio, Sara; Castagnoli, Lorenzo; Nuciforo, Paolo (Publication date: 2023-05-17)

CD36 expression; Breast cancer; Neoadjuvant trastuzumab

MYC: there is more to it than cancer

Zacarias Fluck, Mariano F; Soucek, Laura; Whitfield, Jonathan (Publication date: 2024-03-26)

MYC; Non-oncological diseases; Transcription factor

Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines

Ciardiello, Davide; Belli, Valentina; Matrone, Nunzia; Cardone, Claudia; Martini, Giulia; Vitiello, Pietro Paolo (Publication date: 2019-03-04)

Colorectal cancer; Epidermal growth factor receptor (EGFR); MAPK pathway

Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma

Zacarias Fluck, Mariano F; Massó-Vallés, Daniel; Giuntini, Fabio; González-Larreategui, Íñigo; Kaur, Jastrinjan; Casacuberta-Serra, Sílvia; Jauset González, Antoni; Martínez Martín, Sandra; Martín Fernández, Génesis; Serrano del Pozo, Erika; Foradada Felip, Laia; Grueso Gragera, Judit; Nonell Malezon, Lara; Whitfield, Jonathan; Beaulieu, Marie-Eve; Soucek, Laura (Publication date: 2023-09-26)

MYC; Omomyc; Melanoma

Trotabresib (CC-90010) in combination with adjuvant temozolomide or concomitant temozolomide plus radiotherapy in patients with newly diagnosed glioblastoma

Vieito Villar, Maria; De Vos, Filip; Marjolein Geurts; Lorenzi, Elena; Simonelli, Matteo; Moreno, Victor (Publication date: 2022-12-02)

BET inhibitors; Glioblastoma; Pharmacokinetics

Advances in immune checkpoint inhibitor combination strategies for microsatellite stable colorectal cancer

Ros Montañá, Fco. Javier; Balconi, Francesca; Baraibar Argota, Iosune; Salva Ballabrera, Francesc; Tabernero Caturla, Josep; Elez Fernandez, Mª Elena; Saoudi Gonzalez, Nadia (Publication date: 2023-03-16)

Colorectal cancer; Microsatellite stable; Tyrosine kinase inhibitors

ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

Pascual, Javier; Attard, Gerhardt; Bidard, François-Clement; Diehn, Maximilian; Seoane Suarez, Joan; Curigliano, Giuseppe; De Mattos-Arruda, Leticia (Publication date: 2023-04-17)

Circulating tumour DNA (ctDNA); Liquid biopsy; Precision medicine

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

Strand, Siri H; Rivero-Gutierrez, Belen; Houlahan, Kathleen; Seoane Fernández, Jose Antonio; King, Lorraine M.; Risom, Tyler (Publication date: 2022-12-29)

Ductal carcinoma in situ; Tumor microenvironment; Whole genome sequencing

Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma

Carrasco López, Estela; Del Marro, Sonia; Suñol, Anna; Peral, Jorge; Ortiz, Jessica; Balmaña Gelpí, Judith; Errazquin, Ricardo (Publication date: 2023-04-04)

Fanconi anemia; Cancer gene; Saliva

Isatuximab plus atezolizumab in patients with advanced solid tumors: results from a phase I/II, open-label, multicenter study

Garralda Cabanas, Elena; Eskens, Ferry; Gil-Martin, Marta; Yen, Chia-Jui; Simonelli, Matteo; Santoro, Armando (Publication date: 2023-01-11)

Atezolizumab; Isatuximab; Solid tumors

Sacituzumab govitecan as second-line treatment for metastatic triple-negative breast cancer—phase 3 ASCENT study subanalysis

Carey, Lisa; Loirat, Delphine; Dieras, Veronique; Cortés Castan, Javier; Bardia, Aditya; Punie, Kevin; Dalenc, Florence (Publication date: 2022-09-09)

Breast cancer; Second-line treatment

High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with treatment of physician’s choice—in the EMBRACE study

Miyoshi, Yasuo; Yoshimura, Yuta; Saito, Kenichi; Muramoto, Kenzo; Sugawara, Michiko; Alexis, Karenza; Cortés Castan, Javier (Publication date: 2021-09-16)

Eribulina; Càncer de mama metastàsic; Supervivència global

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023)

Navarro, Miguel; Porras, Ignacio; Hernando, Jorge; Maurente Oliveira, Eduardo; Jimenez Fonseca, Paula; Martinez-Trufero, Javier; Rubió-Casadevall, Jordi (Publication date: 2024-10-31)

Thyroid carcinoma; Molecular alterations; Systemic treatment

Pan-cancer whole-genome comparison of primary and metastatic solid tumours

Movasati, Ali; Brunner, Sascha Remy; Nguyen, Luan; Van Hoeck, Arne; Martínez-Jiménez, Francisco; Priestley, Peter; Cuppen, Edwin (Publication date: 2023-07-04)

Cancer genomics; DNA damage and repair; Metastasis

Towards evidence-based response criteria for cancer immunotherapy

Laurie, Scott; Seymour, Lesley; de Vries, Elisabeth; GARRALDA, Elena (Publication date: 2023-07-04)

Cáncer; Inmunología tumoral

A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer

Garralda Cabanas, Elena; Sukari, Ammar; Patnaik, Amita; Lou, Yanyan; Lakhani, Nehal; Im, Seock-Ah (Publication date: 2023-01-12)

Advanced; Colorectal cancer

AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers

Ruiz Ciancio, Dario; Veeramani, Suresh; Singh, Rahul; Embree, Eric; Ortman, Chris; Thiel, Kristina (Publication date: 2024-12-19)

Aptamer; Bioinformatics; Sequence analysis

Sistema de Salut de Catalunya: Recent submissions

Value of Early Circulating Tumor Cells Dynamics to Estimate Docetaxel Benefit in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients ﻿

RAD51 as a biomarker for homologous recombination deficiency in high-grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test ﻿

Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue ﻿

Predictive Role of CD36 Expression in HER2-Positive Breast Cancer Patients Receiving Neoadjuvant Trastuzumab ﻿

MYC: there is more to it than cancer ﻿

Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines ﻿

Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma ﻿

Trotabresib (CC-90010) in combination with adjuvant temozolomide or concomitant temozolomide plus radiotherapy in patients with newly diagnosed glioblastoma ﻿

Advances in immune checkpoint inhibitor combination strategies for microsatellite stable colorectal cancer ﻿

ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group ﻿

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts ﻿

Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma ﻿

Isatuximab plus atezolizumab in patients with advanced solid tumors: results from a phase I/II, open-label, multicenter study ﻿

Sacituzumab govitecan as second-line treatment for metastatic triple-negative breast cancer—phase 3 ASCENT study subanalysis ﻿

High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with treatment of physician’s choice—in the EMBRACE study ﻿

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023) ﻿

Pan-cancer whole-genome comparison of primary and metastatic solid tumours ﻿

Towards evidence-based response criteria for cancer immunotherapy ﻿

A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer ﻿

AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers ﻿