Título:
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Prevalence of Chagas Disease in Latin-American Migrants Living
in Europe: A Systematic Review and Meta-analysis
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Autor/a:
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Requena-Méndez, Ana; Aldasoro, Edelweiss; Lazzari, Elisa de; Sicuri, Elisa; Brown, Michael; Moore, David A. J.; Gascón i Brustenga, Joaquim; Muñoz, José
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Otros autores:
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Universitat de Barcelona |
Abstract:
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BACKGROUND: Few studies have assessed the burden of Chagas
disease in non-endemic countries and most of them are based on
prevalence estimates from Latin American (LA) countries that
likely differ from the prevalence in migrants living in Europe.
The aim of this study was to systematically review the existing
data informing current understanding of the prevalence of Chagas
disease in LA migrants living in European countries. METHODS: We
conducted a systematic review and meta-analysis of studies
reporting prevalence of Chagas disease in European countries
belonging to the European Union (EU) before 2004 in accordance
with the MOOSE guidelines and based on the database sources
MEDLINE and Global Health. No restrictions were placed on study
date, study design or language of publication. The pooled
prevalence was estimated using random effect models based on
DerSimonian & Laird method. RESULTS: We identified 18
studies conducted in five European countries. The random effect
pooled prevalence was 4.2% (95%CI:2.2-6.7%); and the
heterogeneity of Chagas disease prevalence among studies was
high (I2 = 97%,p<0.001). Migrants from Bolivia had the
highest prevalence of Chagas disease (18.1%, 95%CI:13.9-22.7%).
CONCLUSIONS: Prevalence of Chagas in LA migrants living in
Europe is high, particularly in migrants from Bolivia and
Paraguay. Data are highly heterogeneous dependent upon country
of origin and within studies of migrants from the same country
of origin. Country-specific prevalence differs from the
estimates available from LA countries. Our meta-analysis
provides prevalence estimates of Chagas disease that should be
used to estimate the burden of disease in European countries. |
Materia(s):
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-Malaltia de Chagas -Epidemiologia -Europa -Immigrants -Chagas' disease -Epidemiology -Europe -Immigrants |
Derechos:
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cc by (c) Requena-Méndez et al., 2015
http://creativecommons.org/licenses/by/3.0/es/ |
Tipo de documento:
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Artículo Artículo - Versión publicada |
Editor:
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Public Library of Science (PLoS)
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