dc.contributor.author |
Miloserdov, Fedor M. |
dc.contributor.author |
Kirillova, Mariia S. |
dc.contributor.author |
Muratore, Michael E. |
dc.contributor.author |
Echavarren, Antonio M. |
dc.date.accessioned |
2020-01-21T11:53:23Z |
dc.date.available |
2020-01-21T11:53:23Z |
dc.date.issued |
2018-02-12 |
dc.identifier.uri |
http://hdl.handle.net/2072/368556 |
dc.format.extent |
5393 p. |
dc.language.iso |
eng |
dc.rights |
L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.source |
RECERCAT (Dipòsit de la Recerca de Catalunya) |
dc.subject.other |
54 |
dc.title |
Unified Total Synthesis of Pyrroloazocine Indole Alkaloids Sheds Light on Their Biosynthetic Relationship |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/acceptedVersion |
dc.embargo.terms |
cap |
dc.relation.projectID |
CTQ2016-75960-P MINECO/AEI/FEDER, UE |
dc.relation.projectID |
SEV-2013-0319 |
dc.relation.projectID |
Advanced Grant no. 321066 |
dc.relation.projectID |
2014 SGR 818 |
dc.identifier.doi |
10.1021/jacs.7b13484 |
dc.rights.accessLevel |
info:eu-repo/semantics/openAccess |
dc.description.abstract |
The total synthesis of seven members of the lapidilectine and
grandilodine family of alkaloids has been accomplished in racemic and
enantiopure form without protection/deprotection of functional groups. The
two key steps, an 8-endo-dig hydroarylation and a 6-exo-trig photoredox
cyclization, were catalyzed using gold. A rationale for the formation of the
cyclopropane ring of the lundurines is also provided. |