Título:
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Extending the substrate scope in the hydrogenation of unfunctionalized tetrasubstituted olefins with Ir-P stereogenic aminophosphine-oxazoline catalysts
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Autor/a:
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Biosca, Maria; Salomó, Ernest; Cruz Sánchez, Pol de la; Riera i Escalé, Antoni; Verdaguer i Espaulella, Xavier; Pàmies, Oscar; Diéguez, Montserrat
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Otros autores:
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Universitat de Barcelona |
Abstract:
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Air stable and readily available Ir-catalyst precursors modified with MaxPHOX-type ligands have been successfully applied in the challenging asymmetric hydrogenation of tetrasubstituted olefins under mild reaction conditions. Gratifyingly, these catalyst precursors are not only able to efficiently hydrogenate a range of indene derivatives (ee's up to 96%) but also 1,2-dihydro-napthalene derivatives and acyclic olefins (ee's up to 99%), which both constitute the most challenging substrates for this transformation. |
Materia(s):
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-Hidrogenació -Catàlisi -Lligands (Bioquímica) -Hydrogenation -Catalysis -Ligands (Biochemistry) |
Derechos:
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(c) American Chemical Society , 2019
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Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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American Chemical Society
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Compartir:
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