This paper provides an estimation of air emissions (CO2, NOX, SOX and PM) released by cruise vessels at the port level. The methodology is based on the Bfull bottom-up^ approach and starts by evaluating the fuel consumed by each vessel on the basis of its individual port activities (manoeuvring, berthing and hoteling). The Port of Barcelona was selected as the site at which to perform the analysis, in which 125 calls of 30 cruise vessels were monitored. Real-time data from the automatic identification system (AIS), factor emissions from engine certificates and vessel characteristics from IHS Sea-web database were also collected for the analysis. The research findings show that the most appropriate indicators are inventory emissions per Bport-time gross tonnage^, Bport-time passenger^ and Bport time^. These emission indicators improve our understanding of cruise emissions and will facilitate the work that aims to estimate reliably and quickly the in-port ship emission inventories of cruise ports.