Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress

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dc.contributor	Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa
dc.contributor	Universitat Politècnica de Catalunya. GREMA - Grup de Recerca en Estadística Matemàtica i les seves Aplicacions
dc.contributor.author	Clotet, Bonaventura
dc.contributor.author	Fernández Castro, Jordi
dc.contributor.author	Fumaz, Carmina R.
dc.contributor.author	Gonzalez Garcia, Marian
dc.contributor.author	Borràs, Xavier
dc.contributor.author	Muñoz Moreno, Jose A.
dc.contributor.author	Peña, Ruth
dc.contributor.author	Pérez Álvarez, Nuria
dc.contributor.author	Puig, Jordi
dc.contributor.author	Paredes, Roger
dc.date	2009-11
dc.identifier.citation	Fumaz, C.R. [et al.]. Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress. "JAIDS: journal of acquired immune deficiency syndromes", Novembre 2009, vol. 52, núm. 3, p. 427-428.
dc.identifier.citation	1525-4135
dc.identifier.uri	http://hdl.handle.net/2117/7958
dc.language.iso	eng
dc.relation	http://www.natap.org/2009/HIV/102509_01.htm
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 Spain
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject	Àrees temàtiques de la UPC::Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària
dc.subject	Highly active antiretroviral therapy
dc.subject	HIV infections
dc.subject	Disease Progression
dc.subject	Diseases--Risk factors
dc.subject	Interleukin-6
dc.subject	VIH (Virus) -- Tractament
dc.subject	Factors de risc (Medicina)
dc.subject	Sida
dc.title	Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress
dc.type	info:eu-repo/semantics/publishedVersion
dc.type	info:eu-repo/semantics/article
dc.description.abstract	"In summary, patients who reported high levels of stress had significantly higher levels of peripheral proinflammatory cytokines, especially IL-6. The levels in our patients who reported stress averaged more than 6 times the standard cut off of 2.5 pg/mL, which has been determined to be predictive of physical decline.12 TNF-α levels were also significantly higher in patients with stress. Despite the limited sample size in this pilot study, the findings suggest that psychological stress could be a cofactor in the comorbidity of HIV-infected patients. This hypothesis requires further investigation."

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