Now showing items 1-20 of 61398

    Etiologies and comorbidities of meningitis deaths in children under 5 years in high-mortality settings: Insights from the CHAMPS Network in the post-pneumococcal vaccine era 

    Varo, Rosauro; Xerinda, E.G.; Alam, M.; El Arifeen, S.; Gurley, E.S.; Hossain, M.Z.; Rahman, A.; Akelo, V.; Igunza, K.A.; Onyango, C.; Ameh, S.; Onyango, D.; Bangura, J.S.; Verani, J.R.; Ita, O.; Mutevedzi, P.; Kaluma, E.; Whitney, C.G.; Ogbuanu, I.U.; Blau, D.M.; Gaume, B.; Madhi, S.A.; Kotloff, K.L.; Bassat Orellana, Quique; Sow, S.O.; Tapia, M.D.; Ajanovic, Sara; Mahtab, Sana; Madewell, Z.J.; Baillie, V.; Dangor, Z.; Lala, S.G.; Assefa, N.; Berihun, M.; Madrid, L.; Regassa, L.D.; Scott, J.A.G.; Garrine, M.; Mandomando, Inácio (Publication date: 2026-04-09)

    Background: The role of meningitis in causing deaths and in children under 5 is unclear, especially since widespread use of vaccines to prevent common causes of meningitis. Child Health and Mortality Prevention Surveillance ...

    Ivermectin resistance mechanisms in ectoparasites: a scoping review 

    Furnival-Adams, Joanna Elena Claire; Kiuru, Caroline; Sagna, André Barembaye; Mouline, Karine; Maia, Marta F.; Chaccour, Carlos (Publication date: 2026-04-08)

    Ivermectin mass drug administration has been used for decades to target human and veterinary ectoparasites, and is currently being considered for use against malaria vectors. Although there have been few reports of resistance ...

    Perceptions about oncological physiotherapy among health and social care professionals and cancer care managers: A co-design approach for implementation strategies 

    San Miguel Pagola, Marta; Buesa Estéllez, Almudena; Gargallo Aguarón, Pablo; Roldán Pérez, Patricia; Francín Gallego, Marina; Bellosta López, Pablo; Villa García, Lorena; Medina Rincón, Almudena (Publication date: 2026-04-09)

    Purpose: This study aims to explore the knowledge and perceptions of health and social care professionals (HSCP) as well as cancer care managers and administrators (CCMA) in Spain regarding oncological physiotherapy. It ...

    Nurse-led Management of Atrial Fibrillation in Patients With Implanted Cardiac Devices 

    Cano-Valls, Alba; Martínez Momblán, Ma. Antonia; Domingo Criado, Rebeca; Niebla Bellido, Mireia; Venturas Nieto, Montserrat; Roca Luque, Ivo; Tolosana, José M. (José María); Mont Girbau, Lluís; Guasch i Casany, Eduard (Publication date: 2026-04-09)

    This report describes the management of atrial fibrillation (AFib) events diagnosed through cardiac implantedelectronic devices in an advanced nurse practitioner-led clinic. AFib events necessitating medical evaluationwere ...

    Neuroaxonal Injury May Mediate the Association Between Hyperglycemia and Prognosis in Spontaneous Subarachnoid Hemorrhage 

    Santana Moreno, Daniel; Llull Estrany, Laura; Mosteiro Cadaval, Alejandra; Pedrosa Eguílez, Leire; Pujol Fontrodona, Gabriel; Zattera, Luigi; Werner, Mariano; Martín, Abraham; Justicia Mercader, Carles; Chamorro, Ángel; Torné, Ramón; Amaro Delgado, Sergio (Publication date: 2026-04-09)

    Hyperglycemia during early brain injury (EBI) period after spontaneous subarachnoid hemorrhage (SAH) is associated with poor outcome, but the underlying physiopathology is unknown. This study assessed if hyperglycemia ...

    Acceso tributario a datos bancarios, calidad de la ley y tutela efectiva: comentario a la Stedh Ferrieri y Bonassisa c. Italia, de 8 de enero de 2026 

    Rubio Sánchez, Àlex (Publication date: 2026-04-09)

    Este trabajo analiza la sentencia del Tribunal Europeo de Derechos Humanos en el asunto Ferrieri y Bonassisa c. Italia, de 8 de enero de 2026, desde una perspectiva estrictamente tributaria. Aunque el litigio se resuelve ...

    The case of Spain: Collective creation as political reaction 

    Aragonès Riu, Núria (Publication date: 2026-04-09)

    During the Civil War years (1936–39), several currents of theatrical popular agitation—known as “emergency theatre”—developed in Spain. These movements revived the methods of Russian agitprop theatre,1 introduced in Spain ...

    La Maison d’Alta Costura al París de 1900: un espai de la modernitat, del saló al taller 

    Aragonès Riu, Núria (Publication date: 2026-04-09)

    La ciutat és un territori ple de signes per desxifrar, un teatre de la memòria per revelar, o un paisatge que es pot abordar des de diferents perspectives, com la història cultural dels espais, amb mirades transnacionals ...

    Efficacy and Safety of Glofitamab Plus Polatuzumab Vedotin in Relapsed/Refractory Large B-Cell Lymphoma Including High-Grade B-Cell Lymphoma: Results From a Phase Ib/II Trial 

    Hutchings, Martin; Sureda, Anna; Bosch, Francesc; Stauffer Larsen, Thomas; Corradini, Paolo; Avigdor, Abraham; José Terol, María; Rueda Dominguez, Antonio; Pinto, Antonio; Skarbnik, Alan; Cordoba, Raul; Meszaros Jørgensen, Judit; Luigi Zinzani, Pier; Leung, Wilfred; Bottos, Alessia; Li, Donghang; Relf, James; Tandon, Maneesh; Sellam, Gila; Gritti, Giuseppe (Publication date: 2026-04-09)

    PURPOSEAn unmet need remains for more effective therapies for relapsed/refractory (R/R) large B-cell lymphoma (LBCL), especially high-grade B-cell lymphoma (HGBCL). We present the primary analysis of a phase Ib/II study ...

    TROPION-Lung15: a randomized phase III study of osimertinib combined with datopotamab deruxtecan (Dato-DXd) or Dato-DXd alone versus platinum-doublet chemotherapy in patients with EGFR -mutated advanced non-small cell lung cancer and whose disease has progressed on prior osimertinib 

    Shao-weng Tan, Daniel; Nadal, Ernest; Cheema, Parneet; Wu, Yi-long; Ahn, Myung-ju; Tanizaki, Junko; Grainger, Ellie; Nizialek, Emily; Forcina, Alessandra; Van Der Gronde, Toon; A. Yu, Helena (Publication date: 2026-04-09)

    Background: Osimertinib is the preferred treatment for patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) in several settings; however, disease progression is common, and treatment options after progression ...

    Expanding the spectrum of NUS1-related progressive myoclonic epilepsy: a novel variant and exploratory use of metformin 

    Sau, Cristina; López-rodríguez, Sergi; Falip, Mercè; Esteve-garcia, Anna; Sala-padró, Jacint; Aguilera, Cinthia; Navarro-romero, Alba; Lasa-aranzasti, Amaia; Rodríguez-bel, Laura; Hernández-pérez, Guillermo (Publication date: 2026-04-09)

    Introduction Progressive myoclonic epilepsies (PME) are rare genetic disorders typically presenting with myoclonus, seizures, and cognitive decline. While several genes are associated with PME, the NUS1 gene has recently ...

    Efficacy of Stromal Vascular Fraction Treatment for Knee Osteoarthritis: A Single-Arm Experimental Trial 

    Boada-pladellorens, Anna; Avellanet, Merce; Veiga, Anna; Pages-bolibar, Esther (Publication date: 2026-04-09)

    Background/Objectives: Knee osteoarthritis (KOA) is a common pathology characterized by impaired joint cartilage. Mesenchymal stromal cell (MSC)-based treatments, such as stromal vascular fraction (SVF), are increasingly ...

    Patient-reported outcomes in patients with hematologic malignancies treated with CAR T-cell therapy in Europe 

    R. A. Pennings, Elise; M. Spanjaart, Anne; W. Thielen, Frederick; Oerlemans, Simone; Fleischer, Anna; Sanges, Carmen; Gomes Da Silva, Maria; Cabrerizo, Yolanda; Lecot, Pacôme; Roux-opstaele, Lutgart; Dreuillet, Caroline; Gonzalez-marcano, Eglys; Millán, Olga; Jaeger, Ulrich; Delgado, Julio; Luu, Maik; Huber, Barbara; Lorrain, Margot; Pina, Mariana; Kremer, Andreas; Bolaños, Natacha; Clavreul, Solène; Nier, Samantha; D. K. Liu, Roberto; I. Lissenberg-witte, Birgit; Anguille, Sébastien; Robin, Marie; C. Morris, Emma; Sureda, Anna; Préau, Marie; Pannard, Myriam; H. De Bock, Geertruida; S. Wagers, Scott; Negre, Hélène; Maucort-boulch, Delphine; Hudecek, Michael; A. Uyl-de Groot, Carin; José Kersten, Marie (Publication date: 2026-04-09)

    Patient-reported outcomes (PROs) give direct insights into the treatment's impact on patient's life and complement clinical outcomes. However, since the advent of chimeric antigen receptor T-cell therapy (CAR-T), PROs have ...

    Complications of Haploidentical Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide—A Prospective Study on Behalf of the EBMT Transplant Complications Working Party 

    Tomaszewska, Agnieszka; W. Basak, Grzegorz; Peczynski, Christophe; Polge, Emmanuelle; Ambron, Pascale; Boreland, William; Sica, Simona; Arat, Mutlu; Passweg, Jakob; Luis Lopez Lorenzo, Jose; Salmenniemi, Urpu; Jindra, Pavel; Kulagin, Alexander; Martino Bufarull, Rodrigo; Eder, Matthias; Bekadja, Mohamed-amine; Mussetti, Alberto; E. Graham, Charlotte; Schoemans, Hélène; Penack, Olaf; Moiseev, Ivan; Perić, Zinaida (Publication date: 2026-04-09)

    Background: Haploidentical hematopoietic cell transplantations (haplo-HCTs) with post-transplant cyclophosphamide (PT-Cy) are standard practice, but complications causing morbidity and mortality are not well described. ...

    Use of Cefiderocol for Carbapenem-Resistant Gram-Negative Infections in Hospital at Home: Multicentric Real-World Experience 

    Parra-plaza, Andrea; Ugarte, Ainoa; Benavent, Eva; García-poutón, Nicole; Mujal, Abel; Rosa Oltra, María; Parra-rojas, Andrés; Rico, Verónica; Del Río, Manuel; Nicolás, David (Publication date: 2026-04-09)

    Background: Cefiderocol (CFD) is a novel cephalosporin targeting multidrug-resistant Gram-negative bacterial (GNB) infections. It mimics siderophores to enter into GNB through iron transport receptors. However, evidence ...

    Endoresection in Choroidal Melanoma: Outcomes of Intentional Incomplete Tumor Removal 

    Anduaga Beramendi, Alexander; Caminal Caramés, Marta; Lorenzo Parra, Daniel; Cobos Martín, Estefania; Mateos Olivares, Milagros; García Bru, Pere; Morwani, Rahul; Santamaria Álvarez, Juan; Garcia Garcia, Olga; Arias Barquet, Lluís; Caminal Mitjana, Josep Maria (Publication date: 2026-04-09)

    To assess the outcomes of a modified surgical approach for the treatment of uveal melanoma involving endoresection with intentional residual tumor at the margins, combined with adjuvant ruthenium-106 brachytherapy. This ...

    Association Between Dietary Fatty Acid Intake With Cardiovascular Disease Risk and Serum Lipid Levels 

    Hassanpour Ardekanizadeh, Naeemeh; Abbasi Mobarakeh, Khadijeh; Nami, Sheyda; Shojaei, Maryam; Fazel Nasimi, Seyed; Moradi, Saba; Tejareh, Faezeh; Shekari, Yeganeh; Bahmani, Parsa; Gholamalizadeh, Maryam; Ajami, Marjan; Kooshki, Akram; Doaei, Saeid (Publication date: 2026-04-09)

    Background Despite early interest in the effects of dietary fats on cardiovascular diseases (CVDs), substantial controversy remains regarding the evidence linking different types of fatty acids to CVDs. This study aimed ...

    Long-term liver stiffness dynamics after sustained virological response in patients with HIV/HCV co-infection and advanced fibrosis 

    Martín-carmona, Jesica; Corona-mata, Diana; Téllez, Francisco; Navarrete Lorite, Miguel Nicolás; Barroso, Isabel; Carlos Alados, Juan; Palacios Muñoz, Rosario; De Los Santos, Ignacio; Vera-méndez, Francisco Jesús; Imaz, Arkaitz; Raffo Márquez, Miguel; Morano Vázquez, Aitana Carla; José Galindo, María; Belinchón, Olga; Serrano Fuentes, Miriam; López Zúñiga, Miguel Ángel; Galera Peñaranda, Carlos; Reus-bañuls, Sergio Javier; A. Pineda, Juan; Macías, Juan; Corma-gómez, Anaïs; Gehep-011 Study Group, The (Publication date: 2026-04-09)

    Objective: This study analyses liver stiffness (LS) dynamics in people with HIV (PWH) and advanced liver fibrosis who achieved sustained virological response (SVR) and assess factors associated with LS normalization or ...

    From Evidence to Action: Advancing Timely Implementation of Triple Therapy in Type 2 Diabetes Mellitus and CKD 

    Fernandez-fernandez, Beatriz; Luis Gorriz, Jose; Cebrian-cuenca, Ana; Fácila, Lorenzo; Maria Fernandez Rodriguez, Jose; Perez Maraver, Manuel; Ortiz, Alberto (Publication date: 2026-04-09)

    Amid rapid advances in treating chronic kidney disease (CKD) in type 2 diabetes mellitus (T2DM) and evolving guidelines, implementation remains a major bottleneck. Suboptimal implementation of guidelines, from lack of ...

    Adhesion G protein-coupled receptors 

    Langenhan, Tobias; Anderson, Garret R.; Araç, Demet; Aust, Gabriela; Avila Zozaya, Monserrat; Bagger, Sofie Morsing; Barth, Patrick; Berndt, Sandra; Blacklow, Stephen C.; Blanco Redondo, Beatriz; Boucard, Antony A.; Bridges, James; Brodmerkel, Lara Sophie; Caron, Kathleen M.; Yin, Kwan Chung; Dates, Andrew N.; Araujo Farias, Virginea de; Toro Ruiz, Daniel del; Duman, Joseph G.; Engel, Felix B.; Favara, David M.; Formstone, Caroline J.; Fu, Chaoyu; Garcia De Las Bayonas, Alain; Georgiadi, Anastasia; Gloriam, David E.; Hall, Randy A.; Hamann, Jörg; Hildebrand, Peter W.; Hsiao, Cheng-Chih; Huang, Bill X.; Javitch, Jonathan A.; Kim, Hee-Yong; Kittel, Robert J.; Kleinau, Gunnar; Leduc, Richard; Liebscher, Ines; Lin, Hsi-Hsien; Linnert, Joshua; Ludwig, Marie Gabrielle; Martinelli, David C.; Mathiasen, Signe; Matúš, Daniel; Melkumyan, Mariam; Moreno Salinas, Ana L.; Mulder, Jan; Nash, Michael; Pal, Kasturi; Pederick, Daniel T.; Perry Hauser, Nicole A.; Piao, Xianhua; Ping, Yu-Qi; Placantonakis, Dimitris G.; Pohl, Fabian; Prömel, Simone; Rosenkilde, Mette M.; Sabbagh, Laurent; Sando, Richard C.; Scheerer, Patrick; Schöneberg, Torsten; Seiradake, Elena; Selcho, Mareike; Seufert, Florian; Singh, Abhishek Kumar; Skiniotis, Georgios; Spiess, Katja; Sträter, Norbert; Strutt, David; Südhof, Thomas C.; Sun, Jinpeng; Tall, Gregory G.; Thor, Doreen; Tilley, Douglas G.; Tolias, Kimberley F.; Vallon, Mario; Meir, Erwin G. Van; Vanhollebeke, Benoit; Wiggin, Giselle R.; Wolfrum, Uwe; Yan, Jie; Zaidman, Nathan A.; Zou, Yimin; Scholz, Nicole (Publication date: 2026-04-09)

    Adhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium ...