dc.contributor
Institut Català de la Salut
dc.contributor
[Boada M] Research Center and Memory Clinic, Fundació ACEInstitut Català de Neurociències Aplicades - Universitat Internacional de Catalunya, Barcelona, Spain. Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Barcelona, Spain. [Rodrigo A] GMV SECURE E SOLUTIONS, Valencia, Spain. [Jessen F] Department of Psychiatry, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany. Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, Cologne, Germany. [Wimblad B] Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden. Theme Aging, Karolinska Univ Hospital, Stockholm, Sweden. [Kramberger M] Center for Cognitive Impairments, Department of Neurology, University Medical Center Ljubljana, Ljubljana, Slovenia. [Visser PJ] Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit AmsterdamAmsterdam UMC, Amsterdam, the Netherlands. Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands. [Simó R, Ciudin A] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. CIBER de Diabetes y Enfermedades Metabólicas Asociadas. Instituto de Salud Carlos III, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Boada, Mercè
dc.contributor.author
Rodrigo, Adrián
dc.contributor.author
Jessen, Frank
dc.contributor.author
Wimblad, Bengt
dc.contributor.author
Kramberger, Milika
dc.contributor.author
Visser, Pieter Jelle
dc.contributor.author
Simó Canonge, Rafael
dc.contributor.author
Ciudin Mihai, Andreea
dc.date.accessioned
2025-10-24T08:52:30Z
dc.date.available
2025-10-24T08:52:30Z
dc.date.issued
2022-06-27T11:55:05Z
dc.date.issued
2022-06-27T11:55:05Z
dc.identifier
Boada M, Rodrigo A, Jessen F, Wimblad B, Kramberger M, Visser PJ, et al. Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer’s disease: Results from the MOPEAD project. Alzheimers Dement. 2022 Jun;18(6):1119–27.
dc.identifier
https://hdl.handle.net/11351/7729
dc.identifier
10.1002/alz.12441
dc.identifier
000680909100001
dc.identifier.uri
http://hdl.handle.net/11351/7729
dc.description.abstract
Diagnostic gap; Early diagnosis; Population
dc.description.abstract
Brecha de diagnóstico; Diagnóstico precoz; Población
dc.description.abstract
Bretxa de diagnòstic; Diagnòstic precoç; Població
dc.description.abstract
Introduction: The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among health professionals about the importance of early diagnosis.
Methods: Four different strategies or RUNs were used: (a) a web-based (WB) prescreening tool, (2) an open house initiative (OHI), (3) a primary care-based protocol for early detection of cognitive decline (PC), and (4) a tertiary care-based pre-screening at diabetologist clinics (DC).
Results: A total of 1129 patients at high risk of having prodromal AD or dementia were identified of 2847 pre-screened individuals (39.7%). The corresponding proportion for the different initiatives were 36.8% (WB), 35.6% (OHI), 44.4% (PC), and 58.3% (DC).
Conclusion: These four complementary pre-screening strategies were useful for identifying individuals at high risk of having prodromal or mild AD.
dc.description.abstract
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under Grant Agreement No 115985. This Joint Undertaking receives support from the European Union's Horizon 2020 Research and Innovation program and the European Federation of Pharmaceutical Industries and Associations. www.imi.europa.eu/. All participants provided informed consent.
dc.format
application/pdf
dc.relation
Alzheimer's & Dementia;18(6)
dc.relation
https://doi.org/10.1002/alz.12441
dc.rights
Attribution-NonCommercial 4.0 International
dc.rights
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Alzheimer, Malaltia d' - Diagnòstic
dc.subject
Pacients - Participació
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Cribatge (Medicina)
dc.subject
DISEASES::Nervous System Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease
dc.subject
Other subheadings::Other subheadings::/diagnosis
dc.subject
PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Attitude::Attitude to Health::Treatment Adherence and Compliance::Patient Acceptance of Health Care::Patient Participation
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Mass Screening
dc.subject
ENFERMEDADES::enfermedades del sistema nervioso::enfermedades del sistema nervioso::enfermedades neurodegenerativas::taupatías::enfermedad de Alzheimer
dc.subject
Otros calificadores::Otros calificadores::/diagnóstico
dc.subject
PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::actitud::actitud ante la salud::cumplimiento y adherencia al tratamiento::aceptación de la asistencia sanitaria por parte del paciente::participación del paciente
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::cribado sistemático
dc.title
Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
