dc.contributor
[Castaño-Díez S] Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain. Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Universitat Barcelona, Barcelona, Spain. [Álamo JR, Gómez-Hernando M] Hematopathology Section, Pathology Department, Hospital Clínic Barcelona, Barcelona, Spain. [López-Guerra M] Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Hematopathology Section, Pathology Department, Hospital Clínic Barcelona, Barcelona, Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. [Zugasti I, Jiménez-Vicente C] Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain. [Vela D] Hematology Department, Hospital General de Granollers, Granollers, Spain
dc.contributor
Hospital General de Granollers
dc.contributor.author
Castaño-Díez, Sandra
dc.contributor.author
Gómez-Hernando, Marta
dc.contributor.author
Zugasti, Inés
dc.contributor.author
Jimenez-Vicente, Carlos
dc.contributor.author
Vela, Dolors
dc.contributor.author
Álamo , José Ramón
dc.contributor.author
Lopez-Guerra, Monica
dc.date.accessioned
2026-02-11T20:32:34Z
dc.date.available
2026-02-11T20:32:34Z
dc.date.issued
2026-02-10T11:40:27Z
dc.date.issued
2026-02-10T11:40:27Z
dc.date.issued
2025-02-06
dc.identifier
Castaño-Díez S, Álamo JR, López-Guerra M, Gómez-Hernando M, Zugasti I, Jiménez-Vicente C, et al. Chronic myelomonocytic leukemia with NPM1 mutation or acute myeloid leukemia? Oncologist. 2025 Feb 6;30(2):oyae246.
dc.identifier
http://hdl.handle.net/11351/14233
dc.identifier
10.1093/oncolo/oyae246
dc.identifier.uri
http://hdl.handle.net/11351/14233
dc.description.abstract
Acute myeloid leukemia; Chronic myelomonocytic leukemia; ICC classification
dc.description.abstract
Leucèmia mieloide aguda; Leucèmia mielomonocítica crònica; Classificació de la CCI
dc.description.abstract
Leucemia mieloide aguda; Leucemia mielomonocítica crónica; Clasificación ICC
dc.description.abstract
The 2022 WHO revision and the ICC classification have recently modified the diagnostic criteria for chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia. However, there is no consensus on whether CMML with NPM1 mutation (NPM1mut) should be diagnosed as AML. Nowadays, it is a subject of discussion because of its diagnostic and therapeutic implications. Therefore, we describe a case of a patient diagnosed with CMML NPM1mut and briefly review the literature to highlight the uncertainty about how to classify a CMML with NPM1 mutation. We emphasize the importance of a comprehensive molecular study, which is crucial to optimize the individualized treatment of patients, enabling them to access targeted therapies.
dc.format
application/pdf
dc.publisher
Oxford University Press
dc.relation
The Oncologist;30(2)
dc.relation
https://doi.org/10.1093/oncolo/oyae246
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Leucèmia mieloide aguda
dc.subject
Leucèmia mieloide crònica
dc.subject
DISEASES::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Myeloid::Leukemia, Myeloid, Acute
dc.subject
DISEASES::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Myeloid::Leukemia, Myelomonocytic, Chronic
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Errors
dc.subject
ENFERMEDADES::neoplasias::neoplasias por tipo histológico::leucemia::leucemia mieloide::leucemia mieloide aguda
dc.subject
ENFERMEDADES::neoplasias::neoplasias por tipo histológico::leucemia::leucemia mieloide::leucemia mielomonocítica crónica
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::errores diagnósticos
dc.title
Chronic myelomonocytic leukemia with NPM1 mutation or acute myeloid leukemia?
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
