Sistema de Salut de Catalunya
Institut Català de la Salut
[Lenti MV] Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy. First Department of Internal Medicine, Fondazione IRCCS San Matteo, Pavia, Italy. [Hammer HF] Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University, Graz, Austria. [Tacheci I] 2nd Department of Internal Medicine ‐ Gastroenterology, University Hospital Hradec Králové, Charles University, Faculty of Medicine in Hradec Králové, Hradec Kralove, Czech Republic. [Burgos R] Servei d’Endocrinologia i Nutrició, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Diabetis i Metabolisme, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Schneider S] Gastroenterology and Nutrition, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Nice, France. [Foteini A] 4th Local Primary Care Team, Municipality Practice and Academic Practice of Heraklion, University of Crete, Crete, Greece. [Segarra‐Cantón O] Unitat de Gastroenterologia, Hepatologia, Suport Nutricional i Trasplantaments Hepàtics Pediàtrics, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
2025-10-09T10:15:24Z
2025-10-09T10:15:24Z
2025-06
Breath test; Coeliac disease; Diarrhoea
Prova d'alè; Malaltia celíaca; Diarrea
Prueba del aliento; Enfermedad celíaca; Diarrea
Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption. Patient's medical and pharmacological history are essential for identifying risk factors. Several examinations like endoscopy with small intestinal biopsies, non-invasive functional tests, and radiologic imaging are useful in diagnosing malabsorption. Due to its high prevalence, CD should always be looked for in case of malabsorption with no other obvious explanations and in high-risk individuals. Nutritional support is key in management of patients with malabsorption; different options are available, including oral supplements, enteral or parenteral nutrition. In patients with short bowel syndrome, teduglutide proved effective in reducing the need for parenteral nutrition, thus improving the quality of life of these patients. Primary care physicians have a central role in early detection of malabsorption and should be involved into multidisciplinary teams for improving the overall management of these patients. In this European consensus, involving 10 scientific societies and several experts, we have dissected all the issues around malabsorption, including the definitions and diagnostic testing (Part 1), high-risk categories and special populations, nutritional assessment and management, and primary care perspective (Part 2).
We thank United European Gastroenterology (UEG) for supporting this project and University of Pavia for covering the APC cost.
Article
Published version
English
Decisió, Presa de; Malaltia celíaca; Intestins - Malalties - Tractament; Nutrició; PSYCHIATRY AND PSYCHOLOGY::Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus; DISEASES::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Malabsorption Syndromes; Other subheadings::Other subheadings::/therapy; ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Nutrition Therapy::Nutritional Support; DISEASES::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Malabsorption Syndromes::Celiac Disease; PSIQUIATRÍA Y PSICOLOGÍA::conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso; ENFERMEDADES::enfermedades del sistema digestivo::enfermedades gastrointestinales::enfermedades intestinales::síndromes de malabsorción; Otros calificadores::Otros calificadores::/terapia; TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::terapia nutricional::apoyo nutricional; ENFERMEDADES::enfermedades del sistema digestivo::enfermedades gastrointestinales::enfermedades intestinales::síndromes de malabsorción::enfermedad celíaca
Wiley
United European Gastroenterology Journal;13(5)
https://doi.org/10.1002/ueg2.70011
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
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