dc.contributor
Institut Català de la Salut
dc.contributor
[Jimenez Catalan JJ] Preclinical Imaging Platform, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. [Ferrer Clotas M] Gnotobiotic Core and Mouse Metabolism Core, University of California San Francisco, San Francisco, CA, USA. [Camara Serrano JA] Preclinical Therapeutics Core, University of California San Francisco, San Francisco, CA, USA
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Ferrer Clotas, Marina
dc.contributor.author
Jiménez Catalán, Juan José
dc.contributor.author
Cámara Serrano, Juan Antonio
dc.date.accessioned
2025-10-25T05:37:16Z
dc.date.available
2025-10-25T05:37:16Z
dc.date.issued
2025-09-16T11:01:47Z
dc.date.issued
2025-09-16T11:01:47Z
dc.identifier
Jimenez Catalan JJ, Ferrer Clotas M, Camara Serrano JA. Comparative Analysis of Ultrasonography and MicroCT Imaging for Organ Size Evaluation in Mice. J Imaging. 2025 Jun;11(6):200.
dc.identifier
http://hdl.handle.net/11351/13660
dc.identifier
10.3390/jimaging11060200
dc.identifier
001516809300001
dc.identifier.uri
http://hdl.handle.net/11351/13660
dc.description.abstract
Mice; Organ volume; Ultrasound
dc.description.abstract
Ratolins; Volum d'òrgans; Ecografia
dc.description.abstract
Ratones; Volumen de órganos; Ecografía
dc.description.abstract
In this work, the authors compared microCT and in vivo ultrasonography in terms of accuracy and efficacy for measuring the volume of various organs in mice. Two quantification protocols were applied: ellipsoidal volume measuring maximum diameters in all three axes in both imaging systems and manual delineation of organ borders in microCT studies. The results were compared with ex vivo volumes. In general, both imaging techniques and quantification protocols are accurate, but ultrasound is faster in both acquisition and analysis. The only accurate method for heart volume measurement is manual segmentation on microCT. For the ovary, none of the techniques and protocols had a positive correlation with ex vivo volume. The three-diameter method can be used for ellipsoid organs because of its rapidity, but for more irregular structures, manual segmentation is recommended, although it is time-consuming.
dc.format
application/pdf
dc.relation
Journal of Imaging;11(6)
dc.relation
https://doi.org/10.3390/jimaging11060200
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Rates (Animals de laboratori)
dc.subject
Òrgans (Anatomia)
dc.subject
ORGANISMS::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Eutheria::Rodentia::Muridae::Murinae::Mice
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Ultrasonography
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Radiography::Tomography, X-Ray::Tomography, X-Ray Computed::X-Ray Microtomography
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Organ Size
dc.subject
ORGANISMOS::Eukaryota::animales::Chordata::vertebrados::mamíferos::Eutheria::Rodentia::Muridae::Murinae::ratones
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::ecografía
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::diagnóstico por imagen::radiografía::tomografía de rayos X::tomografía computarizada por rayos X::microtomografía de rayos X
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::exploración física::constitución corporal::pesos y medidas corporales::tamaño de los órganos
dc.title
Comparative Analysis of Ultrasonography and MicroCT Imaging for Organ Size Evaluation in Mice
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
