dc.contributor
Institut Català de la Salut
dc.contributor
[D’Aniello S] Department of Advanced Biomedical Science, University of Napoli “Federico II”, Naples, Italy. [Rustici A] Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy. Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, Bologna, Italy. [Gramegna LL] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servicio de Radiología, Unidad de Neuroradiología, Hospital del Mar, Barcelona, Spain. [Godi C] Neuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Milan, Italy. Neuroradiology Unit, Sant’Antonio Abate Hospital, ASST Valle Olona, Gallarate, Italy. [Piccolo L, Gentile M] Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, Bologna, Italy
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
D’Aniello, Serena
dc.contributor.author
Rustici, Arianna
dc.contributor.author
Gramegna, Laura Ludovica
dc.contributor.author
Godi, Claudia
dc.contributor.author
Piccolo, Laura
dc.contributor.author
gentile, mauro
dc.date.accessioned
2025-10-24T08:49:22Z
dc.date.available
2025-10-24T08:49:22Z
dc.date.issued
2024-05-30T08:17:25Z
dc.date.issued
2024-05-30T08:17:25Z
dc.date.issued
2024-04-29
dc.identifier
D’Aniello S, Rustici A, Gramegna LL, Godi C, Piccolo L, Gentile M, et al. The Contribution of Vessel Wall Magnetic Resonance Imaging to the Diagnosis of Primary and Secondary Central Nervous System Vasculitis. Diagnostics. 2024 Apr 29;14(9):927.
dc.identifier
https://hdl.handle.net/11351/11525
dc.identifier
10.3390/diagnostics14090927
dc.identifier
001219971800001
dc.identifier.uri
http://hdl.handle.net/11351/11525
dc.description.abstract
Cerebral vasculitis; Magnetic resonance; Vessel wall
dc.description.abstract
Vasculitis cerebral; Ressonància magnètica; Paret del vas sanguini
dc.description.abstract
Vasculitis cerebral; Resonancia magnética; Pared del vaso sanguíneo
dc.description.abstract
Background: To describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological brain findings in central nervous system (CNS) vasculitis patients. Methods: Fourteen patients with confirmed CNS Vasculitis from two tertiary centers underwent VW-MRI using a 3T scanner. The images were reviewed by two neuroradiologists to assess vessel wall enhancement characteristics and locations. Results: Fourteen patients were included (six females; average age 48 ± 19 years). Diagnoses included primary CNS vasculitis (PCNSV) in six patients and secondary CNS vasculitis (SCNSV) in eight, half of which were infection-related. Thirteen patients showed vessel wall enhancement, which was intense in eleven patients (84.6%) and concentric in twelve (92.3%), affecting the anterior circulation in nine patients (69.2%), posterior in two patients (15.4%), and both circulations in two patients (15.4%). The enhancement patterns were similar across different CNS vasculitis types. DWI changes corresponded with areas of vessel wall enhancement in 77% of patients. Conclusions: CNS vasculitis is often associated with intense, concentric vessel wall enhancement in VW-MRI, especially in the anterior circulation. The consistent presence of DWI alterations in affected territories suggests a possible link to microembolization or hypoperfusion. These imaging findings complement parenchymal brain MRI and MRA/DSA data, potentially increasing the possibility of a clinical diagnosis of CNS vasculitis.
dc.description.abstract
This study was supported by Associazione Italiana di Neuroradiologia (AINR).
dc.format
application/pdf
dc.relation
Diagnostics;14(9)
dc.relation
https://doi.org/10.3390/diagnostics14090927
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Cervell - Imatgeria per ressonància magnètica
dc.subject
Vasculitis - Diagnòstic
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Sistema nerviós central - Malalties - Diagnòstic
dc.subject
DISEASES::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Vasculitis, Central Nervous System
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Other subheadings::Other subheadings::/diagnosis
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ANATOMY::Nervous System::Central Nervous System::Brain
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Other subheadings::Other subheadings::Other subheadings::/diagnostic imaging
dc.subject
ENFERMEDADES::enfermedades del sistema nervioso::enfermedades autoinmunitarias del sistema nervioso::vasculitis del sistema nervioso central
dc.subject
Otros calificadores::Otros calificadores::/diagnóstico
dc.subject
ANATOMÍA::sistema nervioso::sistema nervioso central::encéfalo
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/diagnóstico por imagen
dc.title
The Contribution of Vessel Wall Magnetic Resonance Imaging to the Diagnosis of Primary and Secondary Central Nervous System Vasculitis
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
