Sistema de Salut de Catalunya
Institut Català de la Salut
[D’Aniello S] Department of Advanced Biomedical Science, University of Napoli “Federico II”, Naples, Italy. [Rustici A] Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy. Neuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, Bologna, Italy. [Gramegna LL] Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Servicio de Radiología, Unidad de Neuroradiología, Hospital del Mar, Barcelona, Spain. [Godi C] Neuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Milan, Italy. Neuroradiology Unit, Sant’Antonio Abate Hospital, ASST Valle Olona, Gallarate, Italy. [Piccolo L, Gentile M] Neurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, Bologna, Italy
Vall d'Hebron Barcelona Hospital Campus
2024-05-30T08:17:25Z
2024-05-30T08:17:25Z
2024-04-29
Cerebral vasculitis; Magnetic resonance; Vessel wall
Vasculitis cerebral; Ressonància magnètica; Paret del vas sanguini
Vasculitis cerebral; Resonancia magnética; Pared del vaso sanguíneo
Background: To describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological brain findings in central nervous system (CNS) vasculitis patients. Methods: Fourteen patients with confirmed CNS Vasculitis from two tertiary centers underwent VW-MRI using a 3T scanner. The images were reviewed by two neuroradiologists to assess vessel wall enhancement characteristics and locations. Results: Fourteen patients were included (six females; average age 48 ± 19 years). Diagnoses included primary CNS vasculitis (PCNSV) in six patients and secondary CNS vasculitis (SCNSV) in eight, half of which were infection-related. Thirteen patients showed vessel wall enhancement, which was intense in eleven patients (84.6%) and concentric in twelve (92.3%), affecting the anterior circulation in nine patients (69.2%), posterior in two patients (15.4%), and both circulations in two patients (15.4%). The enhancement patterns were similar across different CNS vasculitis types. DWI changes corresponded with areas of vessel wall enhancement in 77% of patients. Conclusions: CNS vasculitis is often associated with intense, concentric vessel wall enhancement in VW-MRI, especially in the anterior circulation. The consistent presence of DWI alterations in affected territories suggests a possible link to microembolization or hypoperfusion. These imaging findings complement parenchymal brain MRI and MRA/DSA data, potentially increasing the possibility of a clinical diagnosis of CNS vasculitis.
This study was supported by Associazione Italiana di Neuroradiologia (AINR).
Article
Published version
English
Cervell - Imatgeria per ressonància magnètica; Vasculitis - Diagnòstic; Sistema nerviós central - Malalties - Diagnòstic; DISEASES::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Vasculitis, Central Nervous System; Other subheadings::Other subheadings::/diagnosis; ANATOMY::Nervous System::Central Nervous System::Brain; Other subheadings::Other subheadings::Other subheadings::/diagnostic imaging; ENFERMEDADES::enfermedades del sistema nervioso::enfermedades autoinmunitarias del sistema nervioso::vasculitis del sistema nervioso central; Otros calificadores::Otros calificadores::/diagnóstico; ANATOMÍA::sistema nervioso::sistema nervioso central::encéfalo; Otros calificadores::Otros calificadores::Otros calificadores::/diagnóstico por imagen
MDPI
Diagnostics;14(9)
https://doi.org/10.3390/diagnostics14090927
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
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