dc.contributor
Institut Català de la Salut
dc.contributor
[De Waele JJ] Department of Intensive Care Medicine, Ghent University Hospital,Ghent, Belgium. Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. [Coccolini F] General, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy. [Lagunes L] Grup de Recerca Clínica/Innovació en la Pneumònia i Sèpsia (CRIPS), Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Facultad de Medicina, Universidad Autónoma de San Luis Potosi, San Luis Potosi, Mexico. [Maseda E] Department of Anesthesia and Critical Care, Hospital Quironsalud Valle del Henares, Madrid, Spain. Department of Pharmacology and Toxicology, Complutense University of Madrid, Madrid, Spain. [Rausei S] General Surgery Unit, Department of Surgery, Cittiglio-Angera Hospital, ASST SetteLaghi, Varese, Italy. [Rubio-Perez I] Colorectal Surgery Unit, Department of General Surgery, Hospital Universitario La Paz, Madrid, Spain. Hospital La Paz Institute for Health Research (Idipaz), Madrid, Spain. Universidad Autonoma de Madrid, Madrid, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
De Waele, Jan
dc.contributor.author
Coccolini, Federico
dc.contributor.author
Lagunes, Leonel
dc.contributor.author
Maseda, Emilio
dc.contributor.author
Rausei, Stefano
dc.contributor.author
Rubio-Perez, Ines
dc.date.accessioned
2025-10-25T08:54:46Z
dc.date.available
2025-10-25T08:54:46Z
dc.date.issued
2024-01-24T08:24:30Z
dc.date.issued
2024-01-24T08:24:30Z
dc.date.issued
2023-12-08
dc.identifier
De Waele JJ, Coccolini F, Lagunes L, Maseda E, Rausei S, Rubio-Perez I, et al. Optimized Treatment of Nosocomial Peritonitis. Antibiotics. 2023 Dec 8;12(12):1711.
dc.identifier
https://hdl.handle.net/11351/10886
dc.identifier
10.3390/antibiotics12121711
dc.identifier
001137836700001
dc.identifier.uri
http://hdl.handle.net/11351/10886
dc.description.abstract
Antibiotics; Nosocomial infection; Peritonitis
dc.description.abstract
Antibiòtics; Infecció nosocomial; Peritonitis
dc.description.abstract
Antibióticos; Infección nosocomial; Peritonitis
dc.description.abstract
This comprehensive review aims to provide a practical guide for intensivists, focusing on enhancing patient care associated with nosocomial peritonitis (NP). It explores the epidemiology, diagnosis, and management of NP, a significant contributor to the mortality of surgical patients worldwide. NP is, per definition, a hospital-acquired condition and a consequence of gastrointestinal surgery or a complication of other diseases. NP, one of the most prevalent causes of sepsis in surgical Intensive Care Units (ICUs), is often associated with multi-drug resistant (MDR) bacteria and high mortality rates. Early clinical suspicion and the utilization of various diagnostic tools like biomarkers and imaging are of great importance. Microbiology is often complex, with antimicrobial resistance escalating in many parts of the world. Fungal peritonitis and its risk factors, diagnostic hurdles, and effective management approaches are particularly relevant in patients with NP. Contemporary antimicrobial strategies for treating NP are discussed, including drug resistance challenges and empirical antibiotic regimens. The importance of source control in intra-abdominal infection management, including surgical and non-surgical interventions, is also emphasized. A deeper exploration into the role of open abdomen treatment as a potential option for selected patients is proposed, indicating an area for further investigation. This review underscores the need for more research to advance the best treatment strategies for NP.
dc.description.abstract
J.J.D.W. is supported by the Flanders Research Foundation (1881020N, Sr Clinical Investigator Grant).
dc.format
application/pdf
dc.relation
Antibiotics;12(12)
dc.relation
https://doi.org/10.3390/antibiotics12121711
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Microorganismes - Resistència als medicaments
dc.subject
Peritonitis - Tractament
dc.subject
Medicaments antiinfecciosos - Ús terapèutic
dc.subject
DISEASES::Bacterial Infections and Mycoses::Infection::Intraabdominal Infections::Peritonitis
dc.subject
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents
dc.subject
PHENOMENA AND PROCESSES::Microbiological Phenomena::Drug Resistance, Microbial
dc.subject
DISEASES::Bacterial Infections and Mycoses::Infection::Sepsis
dc.subject
ENFERMEDADES::infecciones bacterianas y micosis::infección::infecciones intraabdominales::peritonitis
dc.subject
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos
dc.subject
FENÓMENOS Y PROCESOS::fenómenos microbiológicos::farmacorresistencia microbiana
dc.subject
ENFERMEDADES::infecciones bacterianas y micosis::infección::sepsis
dc.title
Optimized Treatment of Nosocomial Peritonitis
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
