Sistema de Salut de Catalunya
[Vinuela-Navarro V, Goset J, Aldaba M, Mestre C, Rovira-Gay C, Vilaseca M] Center for Sensors, Instruments and Systems Development, Universitat Politècnica de Catalunya, Terrassa, Spain. [Cano N] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Departament de Ciències Bàsiques, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain. [Ariza M] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. [Delàs B] Servei d'Oftalmologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. [Garolera M] Grup d'Investigació Clínica per a Cervell, Cognició i Comportament, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain. Unitat de Neuropsicologia, Hospital de Terrassa, Consorci Sanitari de Terrassa, Terrassa, Spain
Consorci Sanitari de Terrassa
2023-11-20T10:47:20Z
2023-11-20T10:47:20Z
2023-07-07
COVID-19; Eye movements; Pupil response
COVID-19; Movimientos oculares; Respuesta pupilar
COVID-19; Moviments oculars; Resposta pupil·lar
Eye movement control is impaired in some neurological conditions, but the impact of COVID-19 on eye movements remains unknown. This study aims to investigate differences in oculomotor function and pupil response in individuals who suffer post-COVID-19 condition (PCC) with cognitive deficits. Saccades, smooth pursuit, fixation, vergence and pupillary response were recorded using an eye tracker. Eye movements and pupil response parameters were computed. Data from 16 controls, 38 COVID mild (home recovery) and 19 COVID severe (hospital admission) participants were analyzed. Saccadic latencies were shorter in controls (183 ± 54 ms) than in COVID mild (236 ± 83 ms) and COVID severe (227 ± 42 ms) participants (p = 0.017). Fixation stability was poorer in COVID mild participants (Bivariate Contour Ellipse Area of 0.80 ± 1.61°2 vs 0.36 ± 0.65 °2 for controls, p = 0.019), while percentage of pupil area reduction/enlargement was reduced in COVID severe participants (39.7 ± 12.7%/31.6 ± 12.7% compared to 51.7 ± 22.0%/49.1 ± 20.7% in controls, p < 0.015). The characteristics of oculomotor alterations found in PCC may be useful to understand different pathophysiologic mechanisms.
Project PID2020-112527RB-I00 funded by MCIN/AEI/10.13039/501100011033; La Marató de TV3 Foundation (202111-30-31-32).
Article
Published version
English
Tests neuropsicològics; COVID-19 (Malaltia); Ulls - Moviments; DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections; PHENOMENA AND PROCESSES::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Movement::Eye Movements; PSYCHIATRY AND PSYCHOLOGY::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests; ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus; FENÓMENOS Y PROCESOS::fenómenos fisiológicos nerviosos y musculoesqueléticos::fenómenos fisiológicos musculoesqueléticos::movimiento::movimientos oculares; PSIQUIATRÍA Y PSICOLOGÍA::disciplinas y actividades conductuales::pruebas psicológicas::pruebas neuropsicológicas
Optica Publishing Group
Biomedical Optics Express;14(8)
https://doi.org/10.1364/boe.489037
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
