Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy

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Título:	Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy
Autor/a:	Launay, Nathalie; Ruiz, Montserrat; Grau-López, Laia; Ortega, Francisco J.; Ilieva, Ekaterina V.; Martínez, Juan José; Galea, Elena; Ferrer, Isidro; Knecht, Erwin; Pujol, Aurora; Fourcade, Stéphane
Abstract:	Altres ajuts: We are indebted to the NIH NeuroBioBank for supplying the case material used for the human studies. This study was supported by grants from the European Leukodystrophy Association [ELA2012-033C1], the Center for Biomedical Research on Rare Diseases (CIBERER) to N.L. and M.R. Locomotor experiments were performed by the SEFALer unit F5 led by A.P. which belongs to the CIBERER structure.
Abstract:	The online version of this article (doi:10.1007/s00401-016-1655-9) contains supplementary material, which is available to authorized users.
Materia(s):	-Peroxisome -ER stress -UPR -Oxidative stress -Neurodegeneration -TUDCA -Adrenoleukodystrophy
Derechos:	open access Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by/4.0/
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Uri:	https://ddd.uab.cat/record/186058

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