dc.contributor.author |
Gallemí Rovira, Marçal |
dc.contributor.author |
Molina-Contreras, Maria Jose |
dc.contributor.author |
Paulišić, Sandi |
dc.contributor.author |
Salla-Martret, Mercè |
dc.contributor.author |
Sorin, Céline |
dc.contributor.author |
Godoy, Marta |
dc.contributor.author |
Franco-Zorrilla, Jose Manuel |
dc.contributor.author |
Solano, Roberto |
dc.contributor.author |
Martínez García, Jaime F. |
dc.date |
2017 |
dc.identifier |
https://ddd.uab.cat/record/180255 |
dc.identifier |
urn:10.1111/nph.14727 |
dc.identifier |
urn:oai:ddd.uab.cat:180255 |
dc.identifier |
urn:scopus_id:85046621224 |
dc.identifier |
urn:wos_id:000417215200018 |
dc.identifier |
urn:altmetric_id:24144926 |
dc.identifier |
urn:oai:egreta.uab.cat:publications/367907c6-b82d-4040-af8a-d09837f734ad |
dc.format |
application/pdf |
dc.format |
application/pdf |
dc.language |
eng |
dc.publisher |
|
dc.relation |
Ministerio de Economía y Competitividad SEV-2015-0533 |
dc.relation |
Ministerio de Economía y Competitividad BIO2014-59895-P |
dc.relation |
Ministerio de Economía y Competitividad BIO2011-23489 |
dc.relation |
Agència de Gestió d'Ajuts Universitaris i de Recerca 2014/SGR-447 |
dc.relation |
New phytologist ; Vol. 216, issue 3 (Nov. 2017), p. 798-813 |
dc.rights |
open access |
dc.rights |
Tots els drets reservats. |
dc.rights |
https://rightsstatements.org/vocab/InC/1.0/ |
dc.subject |
Arabidopsis thaliana |
dc.subject |
Arabidopsis thaliana homeobox 4 (ATHB4) |
dc.subject |
DNA-binding activity |
dc.subject |
Ethylene-responsive element binding factor-associated amphiphilic repression (EAR) motif |
dc.subject |
Homeodomain-leucine zipper |
dc.subject |
Shade avoidance syndrome |
dc.title |
A non-DNA-binding activity for the ATHB4 transcription factor in the control of vegetation proximity |
dc.type |
Article |
dc.description.abstract |
Altres ajuts: Generalitat de Catalunya through the CERCA Program |
dc.description.abstract |
In plants, perception of vegetation proximity by phytochrome photoreceptors activates a transcriptional network that implements a set of responses to adapt to plant competition, including elongation of stems or hypocotyls. In Arabidopsis thaliana, the homeodomain-leucine zipper (HD-Zip) transcription factor ARABIDOPSIS THALIANA HOMEOBOX 4 (ATHB4) regulates this and other responses, such as leaf polarity. To better understand the shade regulatory transcriptional network, we have carried out structure-function analyses of ATHB4 by overexpressing a series of truncated and mutated forms and analyzing three different responses: hypocotyl response to shade, transcriptional activity and leaf polarity. Our results indicated that ATHB4 has two physically separated molecular activities: that performed by HD-Zip, which is involved in binding to DNA-regulatory elements, and that performed by the ETHYLENE-RESPONSIVE ELEMENT BINDING FACTOR-associated amphiphilic repression (EAR)-containing N-terminal region, which is involved in protein-protein interaction. Whereas both activities are required to regulate leaf polarity, DNA-binding activity is not required for the regulation of the seedling responses to plant proximity, which indicates that ATHB4 works as a transcriptional cofactor in the regulation of this response. These findings suggest that transcription factors might employ alternative mechanisms of action to regulate different developmental processes. |