Active transcription without histone modifications

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dc.contributor.author	Pérez-Lluch, Sílvia
dc.contributor.author	Guigó Serra, Roderic
dc.contributor.author	Corominas Guiu, Montserrat
dc.date	2015
dc.identifier.citation	Pérez-Lluch S, Guigó R, Corominas M. Active transcription without histone modifications. Oncotarget. 2015; 6(39): 41401. DOI 10.18632/oncotarget.6437
dc.identifier.citation	1949-2553
dc.identifier.citation	http://dx.doi.org/10.18632/oncotarget.6437
dc.identifier.uri	http://hdl.handle.net/10230/26186
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	Impact Journals
dc.relation	Oncotarget. 2015; 6(39): 41401
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	Published originally by Impact Journals at http://dx.doi.org/10.18632/oncotarget.6437 under a Creative Commons Attribution 3.0 License.
dc.rights	http://creativecommons.org/licenses/by/3.0/
dc.subject	Drosòfila
dc.subject	Epigènesi
dc.subject	Chromosome Section
dc.subject	Drosophila
dc.subject	Development
dc.subject	Epigenetics
dc.subject	Transcription
dc.title	Active transcription without histone modifications
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.abstract	Gene expression is regulated by proteins such as transcription factors, as well as by chromatin modifications on DNA and histones. Some histone modifications have been associated to transcriptional activation (i.e. H3K4me1, H3K4me3, H3K9ac, H3K27ac or H3K36me3) whereas others with gene silencing (H3K9me3 and H3K27me3). However, and challenging this premise, we have identified a set of genes in Drosophila melanogaster that are actively expressed in the absence of the canonical histone marks.

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