dc.contributor.author |
Domínguez, Angela |
dc.contributor.author |
Soldevila, Núria |
dc.contributor.author |
Toledo, Diana |
dc.contributor.author |
Godoy i García, Pere |
dc.contributor.author |
Espejo, Elena |
dc.contributor.author |
Fernandez, Maria Amelia |
dc.contributor.author |
Mayoral, José María |
dc.contributor.author |
Castilla, Jesús |
dc.contributor.author |
Egurrola, Mikel |
dc.contributor.author |
Tamames, Sonia |
dc.contributor.author |
Astray, Jenaro |
dc.contributor.author |
Morales, María |
dc.date |
2017-10-19T09:29:52Z |
dc.date |
2017-10-19T09:29:52Z |
dc.date |
2017 |
dc.identifier |
1560-7917 |
dc.identifier |
http://hdl.handle.net/10459.1/60322 |
dc.identifier |
https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602 |
dc.identifier.uri |
http://hdl.handle.net/10459.1/60322 |
dc.description |
Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22–47). VE was 51% (95% CI: 15–71) in patients without high-risk medical conditions and 30% (95% CI: 14–44) in patients with them. VE was 39% (95% CI: 20–53) in patients aged 65–79 years and 34% (95% CI: 11–51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals. |
dc.description |
This work was supported by the National Plan of I+D+I 2008–2011 and ISCIII-Subdirección General de Evaluación y Fomento de la Investigación (Project PI12/02079), and cofunded by Fondo Europeo de Desarrollo Regional (FEDER) and the Catalan Agency for the Management of Grants for University Research (AGAUR grant number 2014/ SGR 1403). |
dc.language |
eng |
dc.publisher |
European Centre for Disease Prevention and Control |
dc.relation |
Reproducció del document publicat a https://doi.org/10.2807/1560-7917.ES.2017.22.34.30602 |
dc.relation |
Eurosurveillance, 2017, vol. 22, núm. 34, p. 1-8 |
dc.rights |
cc-by (c) Domínguez et al., 2017 |
dc.rights |
http://creativecommons.org/licenses/by/4.0/ |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Preventing hospitalisations |
dc.subject |
Elderly individuals |
dc.subject |
Spain |
dc.subject |
Influenza vaccination |
dc.title |
The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15 |
dc.type |
article |
dc.type |
publishedVersion |