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Título:
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Disrupted neural processing of emotional faces in psychopathy
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Autor/a:
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Contreras-Rodríguez, Oren; Pujol Salud, Jesús; Batalla, Iolanda; Harrison, Ben J.; Bosque, Javier; Ibern Regàs, Immaculada; Hernández-Ribas, Rosa; Soriano-Mas, Carles; Deus Yela, Juan; López-Solà, Marina; Pifarré Paredero, Josep; Menchón, José M.; Cardoner, N. (Narcís)
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Notas:
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Psychopaths show a reduced ability to recognize emotion facial expressions, which may disturb the interpersonal relationship development and successful
social adaptation. Behavioral hypotheses point toward an association between emotion recognition deficits in psychopathy and amygdala
dysfunction. Our prediction was that amygdala dysfunction would combine deficient activation with disturbances in functional connectivity with cortical
regions of the face-processing network. Twenty-two psychopaths and 22 control subjects were assessed and functional magnetic resonance maps were
generated to identify both brain activation and task-induced functional connectivity using psychophysiological interaction analysis during an emotional
face-matching task. Results showed significant amygdala activation in control subjects only, but differences between study groups did not reach
statistical significance. In contrast, psychopaths showed significantly increased activation in visual and prefrontal areas, with this latest activation
being associated with psychopaths affective–interpersonal disturbances. Psychophysiological interaction analyses revealed a reciprocal reduction in
functional connectivity between the left amygdala and visual and prefrontal cortices. Our results suggest that emotional stimulation may evoke a
relevant cortical response in psychopaths, but a disruption in the processing of emotional faces exists involving the reciprocal functional interaction
between the amygdala and neocortex, consistent with the notion of a failure to integrate emotion into cognition in psychopathic individuals. |
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Materia(s):
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-Psychopathy
-Face recognition
-FMRI |
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Derechos:
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(c) Oxford University Press, 2014
info:eu-repo/semantics/restrictedAccess |
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Tipo de documento:
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article
publishedVersion |
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Editor:
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Oxford University Press
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Compartir:
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