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Title:
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Assessing the impact of early detection biases on breast cancer survival of Catalan women
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Author:
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Roso-Llorach, Albert; Forné Izquierdo, Carles; Macià, Francesc; Galcerán, Jaume; Marcos-Gragera, Rafael; Rué i Monné, Montserrat
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Notes:
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Survival estimates for women with screen-detected breast cancer are affected by biases specific
to early detection. Lead-time bias occurs due to the advance of diagnosis, and length-sampling
bias because tumors detected on screening exams are more likely to have slower growth than
tumors symptomatically detected. Methods proposed in the literature and simulation were used
to assess the impact of these biases. If lead-time and length-sampling biases were not taken into
account, the median survival time of screen-detected breast cancer cases may be overestimated
by 5 years and the 5-year cumulative survival probability by between 2.5 to 5 percent units. |
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Subject(s):
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-Breast cancer
-Early detection
-Screening
-Lead time bias |
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Rights:
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cc-by-nc-nd, (c) Roso-Llorach et al., 2014
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
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Document type:
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article
publishedVersion |
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Published by:
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Institut d'Estadística de Catalunya
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Share:
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