dc.contributor.author
Zhang, Huihui
dc.contributor.author
Rodrigalvarez, Jesus
dc.contributor.author
Martin, Ruben
dc.date.accessioned
2023-10-31T14:07:02Z
dc.date.accessioned
2024-04-23T10:15:47Z
dc.date.available
2023-10-31T14:07:02Z
dc.date.available
2024-04-23T10:15:47Z
dc.date.issued
2023-08-02
dc.identifier.uri
http://hdl.handle.net/2072/537009
dc.description.abstract
Herein, we report a Ni-catalyzed C(sp2)–H hydroxylation of aryl bromides with N2O as an oxygen-atom donor. The reaction is enabled by a 1,4-Ni translocation that results in ipso/ortho difunctionalized products. Regioselectivity and stereocontrol are dictated by a judicious choice of the ligand backbone, thus giving access to either carbonyl or phenol derivatives and offering an opportunity to repurpose hazardous substances en route to valuable oxygen-containing building blocks.
eng
dc.format.extent
6 p.
cat
dc.publisher
ACS Publications
cat
dc.rights
CC-BY-NC-ND 4.0.
dc.source
RECERCAT (Dipòsit de la Recerca de Catalunya)
dc.subject.other
Química
cat
dc.title
C(sp2)–H Hydroxylation via Catalytic 1,4-Ni Migration with N2O
cat
dc.type
info:eu-repo/semantics/article
cat
dc.type
info:eu-repo/semantics/publishedVersion
cat
dc.relation.projectID
FEDER/MCI PID2021-123801NB-I00
cat
dc.relation.projectID
MCI/AIE (Severo Ochoa Excellence Accreditation 2002-2023, CEX2019-000925-S)
cat
dc.relation.projectID
J.R. and H.Z. thank the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement 101105032 (CARBO-CHAIN)
cat
dc.relation.projectID
and China Scholarship Council (CSC) for a predoctoral fellowship.
cat
dc.identifier.doi
https://doi.org/10.1021/jacs.3c07018
dc.rights.accessLevel
info:eu-repo/semantics/openAccess
