Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series

dc.contributor.author
Moriña, D.
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Fernández-Fontelo, A.
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Cabaña, A.
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Arratia, A.
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Puig, P.
dc.date.accessioned
2023-06-21T08:40:17Z
dc.date.accessioned
2024-09-19T14:25:30Z
dc.date.available
2023-06-21T08:40:17Z
dc.date.available
2024-09-19T14:25:30Z
dc.date.issued
2023-03-28
dc.identifier.uri
http://hdl.handle.net/2072/535444
dc.description.abstract
Background: The problem of dealing with misreported data is very common in a wide range of contexts for different reasons. The current situation caused by the Covid-19 worldwide pandemic is a clear example, where the data provided by official sources were not always reliable due to data collection issues and to the high proportion of asymptomatic cases. In this work, a flexible framework is proposed, with the objective of quantifying the severity of misreporting in a time series and reconstructing the most likely evolution of the process. Methods: The performance of Bayesian Synthetic Likelihood to estimate the parameters of a model based on AutoRegressive Conditional Heteroskedastic time series capable of dealing with misreported information and to reconstruct the most likely evolution of the phenomenon is assessed through a comprehensive simulation study and illustrated by reconstructing the weekly Covid-19 incidence in each Spanish Autonomous Community. Results: Only around 51% of the Covid-19 cases in the period 2020/02/23–2022/02/27 were reported in Spain, showing relevant differences in the severity of underreporting across the regions. Conclusions: The proposed methodology provides public health decision-makers with a valuable tool in order to improve the assessment of a disease evolution under different scenarios. © 2023, The Author(s).
eng
dc.description.sponsorship
Fundación Mapfre; Ministerio de Ciencia e Innovación, MICINN: ANR-16-IDEX-0008, CY-AAP2020-0000000013, RTI2018-096072-B-I00; Agencia Estatal de Investigación, AEI: CEX2020–001084-M, IJC2020-045188I/AEI/10.13039/501100011033, PID2021-123733NB-I00. Research funded by Fundación MAPFRE. This work was partially supported by grant RTI2018-096072-B-I00 from the Spanish Ministry of Science and Innovation and by the Spanish State Research Agency, through the Severo Ochoa and María de Maeztu Program for Centers and Units of Excellence in R&D (CEX2020–001084-M). A.F-F acknowledges Agencia Estatal de Investigación for the financial support IJC2020-045188I/AEI/10.13039/501100011033. AC was partially financed by PID2021-123733NB-I00 (Ministerio de Ciencia e Innovación, Spain). AC and AA were partially supported by Project “EcoDep” CY-AAP2020-0000000013 (“Investissements d’Avenir” ANR-16-IDEX-0008, France).
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8 p.
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dc.language.iso
eng
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dc.relation.ispartof
BioMed Central Ltd
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dc.rights
L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: https://creativecommons.org/licenses/by/4.0/
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RECERCAT (Dipòsit de la Recerca de Catalunya)
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ARCH models; Bayesian synthetic likelihood; Continuous time series; Covid-19; Infectious diseases; Mixture distributions; Under-reported data
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dc.title
Estimated Covid-19 burden in Spain: ARCH underreported non-stationary time series
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info:eu-repo/semantics/article
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dc.type
info:eu-repo/semantics/publishedVersion
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dc.embargo.terms
cap
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dc.identifier.doi
10.1186/s12874-023-01894-9
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dc.rights.accessLevel
info:eu-repo/semantics/openAccess


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