dc.contributor.author |
Hernando Rovirola, Cristina |
dc.contributor.author |
Spiteri, Gianfranco |
dc.contributor.author |
Sabidó Espin, Meritxell |
dc.contributor.author |
Montoliu, Alexandra |
dc.contributor.author |
Gonzalez Soler, Victoria |
dc.contributor.author |
Casabona-Barbarà, Jordi |
dc.contributor.author |
Cole, Michelle Jayne |
dc.contributor.author |
Noori, Teymur |
dc.contributor.author |
Unemo, Magnus |
dc.date |
2020 |
dc.identifier |
https://ddd.uab.cat/record/226239 |
dc.identifier |
urn:10.1136/sextrans-2018-053912 |
dc.identifier |
urn:oai:ddd.uab.cat:226239 |
dc.identifier |
urn:pmid:32019895 |
dc.identifier |
urn:pmcid:PMC7231443 |
dc.identifier |
urn:pmc-uid:7231443 |
dc.identifier |
urn:articleid:14723263v96p204 |
dc.identifier |
urn:oai:pubmedcentral.nih.gov:7231443 |
dc.format |
application/pdf |
dc.language |
eng |
dc.publisher |
|
dc.relation |
Sexually Transmitted Infections ; Vol. 96 (february 2020), p. 204-210 |
dc.rights |
open access |
dc.rights |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. |
dc.rights |
https://creativecommons.org/licenses/by-nc/4.0/ |
dc.subject |
Gonorrhoea |
dc.subject |
Treatment |
dc.subject |
Ceftriaxone |
dc.subject |
Antimicrobial resistance |
dc.subject |
Surveillance |
dc.subject |
Euro-GASP |
dc.subject |
Europe |
dc.subject |
Migrants |
dc.title |
Antimicrobial resistance in Neisseria gonorrhoeae isolates from foreign-born population in the European Gonococcal Antimicrobial Surveillance Programme |
dc.type |
Article |
dc.description.abstract |
International spread has contributed substantially to the high prevalence of antimicrobial resistant (AMR) Neisseria gonorrhoeae infections worldwide. We compared the prevalence of AMR gonococcal isolates among native persons to foreign-born (reporting country different from country of birth) persons, and describe the epidemiological and clinical characteristics of foreign-born patients and their associations to AMR. We analysed isolates and patient data reported to the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP) 2010-2014 (n=9529). Forty-three per cent of isolates had known country of birth and 17.2% of these were from persons born abroad. Almost 50% of foreign-born were from the WHO European Region (13.1% from non-European Union [EU] and the European Economic Area [EEA] countries). Compared with isolates from natives, isolates from foreign-born had a similar level (p>0.05) of azithromycin resistance (7.5% vs 7.2%), ciprofloxacin resistance (50.0% vs 46.3%) and of decreased susceptibility to ceftriaxone (1.9% vs 2.8%); a lower rate of cefixime resistance (5.7% vs 3.6%, p=0.02), and a higher proportion of isolates producing penicillinase (8.4% vs 11.7%, p=0.02). Among isolates from persons born outside EU/EEA, the level of decreased susceptibility to ceftriaxone was higher (1.8% vs 3.5%, p=0.02), particularly in those from the WHO Eastern Mediterranean Region and non-EU/EEA WHO European countries (1.9% vs 9.6% and 8.7%, respectively, p<0.01). In multivariable analysis, foreign-born patients with AMR isolates were more likely to be from non-EU/EEA WHO European countries (adjusted OR [aOR]: 3.2, 95% CI 1.8 to 5.8), WHO Eastern Mediterranean countries (aOR: 1.8, 95% CI 1.1 to 3.3) and heterosexual males (aOR: 1.8, 95% CI 1.2 to 2.7). Importation of AMR strains remains an important threat in the EU/EEA. Research to improve understanding of sexual networks within foreign born and sexual tourism populations could help to inform effective tailor-made interventions. The Euro-GASP demonstrates the public health value of quality-assured surveillance of gonococcal AMR and the need for strengthened AMR surveillance, particularly in the non-EU/EEA WHO European Region. |