dc.contributor.author |
Romero-Aroca, Pedro |
dc.contributor.author |
Baget-Bernaldiz, Marc |
dc.contributor.author |
Navarro-Gil, Raul |
dc.contributor.author |
Moreno-Ribas, Antonio |
dc.contributor.author |
Valls-Mateu, Aida |
dc.contributor.author |
Sagarra-Alamo, Ramon |
dc.contributor.author |
Barrot de la Puente, Joan |
dc.contributor.author |
Mundet-Tudurí, Xavier |
dc.contributor.author |
Universitat Autònoma de Barcelona |
dc.date |
2018 |
dc.identifier |
https://ddd.uab.cat/record/190789 |
dc.identifier |
urn:10.1155/2018/5637130 |
dc.identifier |
urn:oai:ddd.uab.cat:190789 |
dc.identifier |
urn:pmid:29682579 |
dc.identifier |
urn:pmcid:PMC5846354 |
dc.identifier |
urn:pmc-uid:5846354 |
dc.identifier |
urn:scopus_id:85048687688 |
dc.identifier |
urn:wos_id:000427167200001 |
dc.identifier |
urn:oai:egreta.uab.cat:publications/5e04a38f-276f-4131-b7fe-c055a05c962e |
dc.identifier |
urn:oai:pubmedcentral.nih.gov:5846354 |
dc.format |
application/pdf |
dc.language |
eng |
dc.publisher |
|
dc.relation |
Instituto de Salud Carlos III FI12-01535 |
dc.relation |
Instituto de Salud Carlos III FI15-01150 |
dc.relation |
Journal of Diabetes Research ; Vol. 2018 (february 2018) |
dc.rights |
open access |
dc.rights |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
dc.rights |
https://creativecommons.org/licenses/by/4.0/ |
dc.title |
Glomerular Filtration Rate and/or Ratio of Urine Albumin to Creatinine as Markers for Diabetic Retinopathy : A Ten-Year Follow-Up Study |
dc.type |
Article |
dc.description.abstract |
To determine the relationship between diabetic nephropathy and diabetic retinopathy on a population of type 2 diabetes mellitus patients. A prospective ten-year follow-up population-based study. We determined differences between estimated glomerular filtration rate (eGFR) using the chronic kidney disease epidemiology collaboration equation and urine albumin to creatinine ratio. Annual incidence of any-DR was 8.21 ± 0.60% (7.06%-8.92%), sight-threatening diabetic retinopathy (STDR) was 2.65 ± 0.14% (2.48%-2.88%), and diabetic macular edema (DME) was 2.21 ± 0.18% (2%-2.49%). Renal study results were as follows: UACR > 30 mg/g had an annual incidence of 7.02 ± 0.05% (6.97%-7.09%), eGFR < 60 ml/min/1.73 m 2 incidence was 5.89 ± 0.12% (5.70%-6.13%). Cox's proportional regression analysis of DR incidence shows that renal function studied by eGFR < 60 ml/min/1.73 m 2 was less significant (p = 0.04, HR 1.223, 1.098-1.201) than UACR ≥ 300 mg/g (p < 0.001, HR 1.485, 1.103-1.548). The study of STDR shows that eGFR < 60 ml/min/1.73 m 2 was significant (p = 0.02, HR 1.890, 1.267-2.820), UACR ≥ 300 mg/g (p < 0.001, HR 2.448, 1.595-3.757), and DME shows that eGFR < 60 ml/min/1.73 m 2 was significant (p = 0.02, HR 1.920, 1.287-2.864) and UACR ≥ 300 mg/g (p < 0.001, HR 2.432, 1.584-3.732). The UACR has a better association with diabetic retinopathy than the eGFR, although both are important risk factors for diabetic retinopathy. |