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IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer: Recent submissions

Now showing items 1-20 of 3203

    Consensus on Subdomains and Measures of Relevance to Affective and Social Cognition Research on Bipolar Disorder (CAS-BD); Outcomes and Recommendations From an International Society for Bipolar Disorders Targeting Cognition Taskforce Study 

    Van Rheenen, Tamsyn E Van; Lewandowski, Kathryn E; Pinkham, Amy; Varo, Cristina; Caruana, Georgia F.; Gruber, J.; Zarp, Jeff; Young, Allan H.; Yatham, Lakshmi N.; Vieta i Pascual, Eduard, 1963-; Torres, Ivan J.; Tsapekos, Dimosthenis; Sumiyoshi, Tomiki; Stokes, Paul R. A.; Schaffer, Ayal; Purdon, Scot E.; Porter, Richard J.; McIntyre, Roger S.; Martínez-Arán, Anabel, 1971-; López Jaramillo, Carlos; Lafer, Beny; Kessing, Lars Vedel; Kjærstad, Hanne Lie; Hasler, Gregor; Gallagher, Peter; Douglas, Katie; Dols, Annemiek; Carvalho, André F.; Burdick, Katherine E.; Bowie, Christopher R.; Bonnín Roig, Caterina del Mar; Balanzá-Martínez, Vicent; Miskowiak, Kamilla W. (Publication date: 2026-03-24)

    Background The Consensus on subdomains and measures of Affective and Social cognition for research on Bipolar Disorder (CAS-BD) project aimed to formulate preliminary consensus-based recommendations for assessing affective ...

    Psychosocial functional recovery in patients with bipolar disorder in remission: Which symptoms hold them back? 

    Bonnín Roig, Caterina del Mar; Montejo Egido, Laura; Torrent Font, Carla; Sánchez Moreno, José; Diego-Adeliño, Javier de; Solé Cabezuelo, Brisa; Roca Tutusaus, Xavier; Hidalgo Mazzei, Diego; Borràs, Roger; Clougher, Derek; Valentí Ribas, Marc; Martínez-Arán, Anabel, 1971-; Cardoner, N. (Narcís); Vieta i Pascual, Eduard, 1963- (Publication date: 2026-03-24)

    Background: Subthreshold depressive symptoms significantly hinder functional recovery in bipolar disorder (BD). While most studies use a global score to assess the impact of these symptoms on functioning, this study examines ...

    Murine typhus as the leading cause of non-focalized fever in the Canary Islands 

    Vélez-Tobarias, Mónica; Torres-Vega, Ana María; Carmelo Pascual, Emma; Morais-Martín, Julio; Pérez, José Antonio; Gonzalo-Hernández. C.; Clot Razquin, Guillem; Ascaso Terrén, Carlos (Publication date: 2026-03-24)

    Purpose and methods: This prospective study aims to diagnose the etiology of non-focalized fever lasting between 5 and 28 days in the islands of La Palma and El Hierro (Canary Islands, Spain) during 2021, using serology ...

    Protocol for tailored in vitro neuronal networks on high-density microelectrode arrays with polydimethylsiloxane microstructures 

    Haeb, Anna-Christina; Yamamoto, Hideaki; Roach, Paul; Merryweather, Daniel; Sato, Y.; Tornero, Daniel; Soriano i Fradera, Jordi (Publication date: 2026-03-18)

    Complementary metal-oxide-semiconductor (CMOS)-based high-density microelectrode arrays (HD-MEAs) enable neuronal recordings with high spatiotemporal resolution. However, integrating polydimethylsiloxane (PDMS) microstructures ...

    Haematopoietic stem cell transplant versus immune-reconstitution therapy in relapsing multiple sclerosis. 

    Blanco Morgado, Yolanda; Kalincik T; Sharmin S; Roos I; Freedman MS; Atkins H; Massey J; Sutton I; Withers B; Burman J; Torkildsen Ø; Bø L; Lehmann AK; Havrdova EK; Krasulova E; Trneny M; Kozak T; Macdonell R; Brown JWL; Coles A; Van der Walt A; Butzkueven H; Van Wijmeersch B; Lechner-Scott J; Barnett M; Laureys G; Willekens B; Buzzard K; Skibina O; Di Gregorio M; Hodgkinson S; Ozakbas S; Meca-Lallana JE; Alroughani R; Prevost J; Foschi M; Surcinelli A; Neri S; Eichau S; McCombe P; John N (Publication date: 2026-03-17)

    In the treatment of relapsing-remitting multiple sclerosis, autologous hematopoietic stem cell transplant and immune-reconstitution therapies show several similarities. These treatment strategies have not yet been compared ...

    XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (I) 

    Fernández, Óscar; Arés, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Caminero, Ana Belén; Castillo-triviño, Tamara; Costa-frossard, Lucienne; Eichau, Sara; Hernández, Miguel Ángel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; E. Meca-lallana, José; Meca-lallana, Virginia; Moral, Ester; Oreja-guevara, Celia; María Prieto, José; Romero-pinel, Lucía; Vilaseca, Andreu; Rodríguez-antigüedad, Alfredo (Publication date: 2026-03-17)

    Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...

    XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II) 

    Fernández, Óscar; Arés, Adrián; Agüera, Eduardo; Aladro, Yolanda; Alonso, Ana; Arroyo, Rafael; Brieva, Luis; Calles, Carmen; Belén Caminero, Ana; Castillo-triviño, Tamara; Costa-frossard, Lucienne; Eichau, Sara; Ángel Hernández, Miguel; Landete, Lamberto; Llaneza, Miguel; Llufriu, Sara; E. Meca-lallana, José; Meca-lallana, Virginia; Moral, Ester; Oreja-guevara, Celia; María Prieto, José; Romero-pinel, Lucía; Vilaseca, Andreu; Rodríguez-antigüedad, Alfredo (Publication date: 2026-03-17)

    Introduction: The XVII edition of the post-European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting was held on 4-5 October 2024 in Madrid. This event was attended by Spanish neurologists ...

    Metabolic Singularities in Microsatellite-Stable Colorectal Cancer: Identifying Key Players in Immunosuppression to Improve the Immunotherapy Response. 

    Gorría, Teresa; Sierra-Boada, Marina; Rojas, Mariam; Figueras, Carolina; Marín Martínez, Silvia; Madurga Díez, Sergio; Cascante i Serratosa, Marta; Maurel Santasusana, Joan (Publication date: 2026-03-03)

    Although immune checkpoint inhibitor (ICI) therapy is currently the standard of care in microsatellite-unstable (MSI) metastatic colorectal cancer (CRC), ICI therapy, alone or in combination with other therapies, is not a ...

    HBV Suppression by Nucleos(t)ide Analogues Reduces PD-1 Expression on Liver-Resident T Cells 

    Garcia Lopez, Mireia; Lens García, Sabela; Pallett, Laura J; Pocurull Aparicio, Anna; Leonel Couto, Thais; Belmonte, Ernest; Garcia Pras, Ester; Rodríguez Tajes, Sergio; Mariño Mendez, Zoe; Sàez Palma, Maria; Bartres, Concepcion; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco; Lin, Jonah; Gehring, Adam J; MAINI, MALA K; Forns Bernhardt, Xavier; Pérez Del Pulgar Gallart, Sofía (Publication date: 2026-02-27)

    Background and Aim: PD-1-expressing T cells within the HBV-infected liver constitute a target of novel immunotherapeutics. Our aim was to investigate the impact of viral suppression on PD-1 expression on intrahepatic versus ...

    Higher seroprevalence of hepatitis E virus in autoimmune hepatitis: Role of false-positive antibodies 

    Llovet, Laura Patricia; Londoño, María Carlota; Gratacós Ginès, Jordi; Ortiz, Oswaldo; Rodriguez Tajes, Sergio; Lens García, Sabela; Reverter, Enric; Ruiz Ortiz, Estíbaliz; Costa Faidella, Jordi; Viñas, Odette; Forns, Xavier; Parés Darnaculleta, Albert (Publication date: 2026-02-27)

    Background and aims Recent studies have found an increase in the seroprevalence of hepatitis E virus (HEV) infection in patients with autoimmune hepatitis (AIH). We aimed to assess the prevalence of positive anti-HEV IgM ...

    Presentation and Outcomes of Pregnancy in Patients With Autoimmune Hepatitis 

    Llovet LP; Horta D; Eliz MG; Berenguer M; Fábrega E; Sáez-Royuela F; Garcia-Retortillo M; Torrijos YS; Romero-Gomez M; Fernandez C; Domínguez EG; Parés Darnaculleta, Albert; Londoño Hurtado, María Carlota (Publication date: 2026-02-26)

    Autoimmune hepatitis (AIH) frequently affects women of childbearing age in whom the desire to have a family raises the question regarding the potential risks for the fetus and the mother. The information on AIH in pregnant ...

    Vestibulo-ocular reflex assessed with Video Head Impulse Test in children with Vestibular Migraine: Our experience 

    Rodríguez-Villalba, Rosana; Caballero Borrego, Miguel; Villarraga, Vanessa; de Jesus, Victoria Rivero; Claveria, Maria Antonia; Haag, Oliver (Publication date: 2026-02-26)

    Vestibular Migraine in children can mimic other disorders, especially at presentation. Outcome is hard to predict and management may be challenging due to the fact that many of the patients are too young to describe their ...

    A cross-sectional pilot study to define anal cancer risk factors in HIV-positive solid organ transplant recipients. 

    Fuertes, Irene; Chivite, Ivan; Cranston, R.D.; Sánchez, Emilia; Lazzari, Elisa de; Marimon, Lorena; Ordi i Majà, Jaume; Miró Meda, José M. (José María), 1956-; Blanco, José L. (Publication date: 2026-02-25)

    Background HIV-positive organ transplant recipients are at high risk of anal cancer, but there are no data on the prevalence of high-risk human papillomavirus (hr-HPV) or anal dysplasia, in this population. Objective To ...

    Infective endocarditis after transcatheter versus surgical aortic valve replacement 

    Panagides, Vassili; Cuervo Requena, Guillermo; Llopis Pérez, Jaime; Abdel-wahab, Mohamed; Mangner, Norman; Habib, Gilbert; Regueiro, Ander; Mestres, Carlos A.; Tornos, Pilar; Durand, Eric; Selton Suty, Christine; Ihlemann, Nikolaj; Bruun, Niels E; Urena, Marina; Cecchi, Enrico; Thiele, Holger; Durante Mangoni, E.; Pellegrini, Costanza; Eltchaninoff, Helene; Athan, Eugene; Søndergaard, Lars; Linke, Axel; Tattevin, Pierre; Val, David del; Quintana, Eduard; Chu, Vivian; Rodés Cabau, Josep; Miró Meda, José M. (José María), 1956-; TAVI Infective Endocarditis International Registry and ICE Investigators (Publication date: 2026-02-24)

    Abstract Background Scarce data are available comparing infective endocarditis (IE) following surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR). This study aimed to compare the ...

    A contemporary picture of coagulase-negative staphylococcal endocarditis: a Nationwide GAMES Cohort Study 

    Palom Grau, Clara; Cuervo Requena, Guillermo; Muñoz, Patricia; Marín, Mercedes; Martínez Sellés, Manuel; González Ramallo, Víctor; Alarcón, Aristides de; Poyato Borrego, Manuel; Rodríguez García, Raquel; Rodríguez Esteban, María Ángeles; Fariñas, María Carmen; González-Rico, Claudia; Goenaga Sánchez, Miguel Ángel; Ojeda Burgos, Guillermo; Goikoetxea Agirre, Ane Josune; Calderón Parra, Jorge; López Azor, Juan Carlos; García Vázquez, Elisa; Loeches, Belén; Quintana, Eduard; García de la Mària, Cristina; Llopis Pérez, Jaime; Miró Meda, José M.; the GAMES Investigators (Publication date: 2026-02-24)

    Background Coagulase-negative staphylococci (CoNS) are an increasingly common cause of infective endocarditis (IE) and lack recent data from large studies. Objectives Our aim was to describe the epidemiology, clinical ...

    Characteristics and outcome of acute heart failure in infective endocarditis: focus on cardiogenic shock. 

    Pericàs, Juan M.; Hernández Meneses, Marta; Muñoz, Patricia; Martínez Sellés, Manuel; Álvarez Uria, Ana; Alarcón, Aristides de; Gutiérrez Carretero, Encarnación; Goenaga Sánchez, Miguel Ángel; Zarauza Navarro, Manuel Jesús; Falces Salvador, Carles; Rodríguez Esteban, María Ángeles; Hidalgo Tenorio, Carmen; Hernández Cabrera, Michele; Miró Meda, José M.; Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES) (Publication date: 2026-02-24)

    Background: Studies investigating the impact of cardiogenic shock (CS) on endocarditis are lacking. Methods: Prospectively collected cohort from 35 Spanish centers (2008-2018). Logistic regression analyses were performed ...

    Antidepressant use in older age bipolar disorder (OABD): Results from the GAGE-BD international consortium 

    Rigas, Christina; Lafer, Beny; Mulsant, Benoit; Oluwaniyi, Stephen O.; Patrick, Regan; Radua, Joaquim; Sarna, Kaylee; Schouws, Sigfried; Simhandl, Christian; Soares, Jair C; Sutherland, Ashley N.; Almeida, Osvaldo P.; Tsai, Shang-Ying; Altinbas, Krusat; Vieta i Pascual, Eduard, 1963-; Balanzá-Martínez, Vicent; Villa, Luca M.; Barbosa, Izabela G.; Fiorelli, Nicole; Blumberg, Hilary P.; Villela Nunes, Paula; Briggs, Farren B. S.; Yala, Joy M.; Calkin, Cynthia V.; Sajatovic, Martha; Forester, Brent P.; Rej, Soham; Forlenza, Orestes V.; Hajek, Tomas; Lavin, Paola; Chen, Peijun; Torres Platas, Susana G.; Su, Chien-Lin; Eyler, Lisa T.; Olagunju, Andrew T.; Teixeira, Antonio L.; Dols, Annemiek; Alda, Martin; Haarman, Bartholomeus; Jiménez Martínez, Esther (Publication date: 2026-02-23)

    Background Antidepressants are still commonly prescribed in bipolar disorders, despite ongoing controversy of the potential risk of inducing hypomania/mania. There is limited knowledge about the characteristics of ...

    Lung function predicts mortality in people with serious mental illness: A 6-year follow-up study 

    Jaén Moreno, María José; Laguna Muñoz, David; Del Pozo, Gloria Isabel; Camacho Rodríguez, Cristina; Guler, Ipek; Alcalá, José Ángel; Reyes López, Micaela; Alcántara García, Montserrat; Benítez Jurado, Diego; Ruiz Rull, Cristina; Jiménez Peinado, Ana; Feu, Nuria; Vieta i Pascual, Eduard, 1963-; Balanzá-Martínez, Vicent; Sarramea, Fernando (Publication date: 2026-02-23)

    Background: The population with a serious mental illness (SMI) shows a high risk of premature mortality. Overexposed to multiple health risks throughout life, their main threat is physical illness, which starts earlier and ...

    Olfactory impairment in Parkinson's disease and white matter abnormalities in central olfactory areas: a voxel-based diffusion tensor imaging study 

    Ibarretxe-Bilbao, Naroa; Junqué i Plaja, Carme, 1955-; Martí Domènech, Ma. Josep; Valldeoriola Serra, Francesc; Vendrell i Gómez, Pere; Bargalló Alabart, Núria; Zarei, Mojtaba; Tolosa, Eduardo (Publication date: 2026-02-23)

    Olfactory dysfunction is known to occur before the appearance of the classical motor signs in Parkinson's disease (PD) and diffusion tensor imaging (DTI) studies in PD have reported fractional anisotropy (FA) reductions ...

    Current perspectives on psychedelic treatments in Europe 

    Madero Gómez, Santiago; Soto Angona, Oscar; Ona, Genis; Sánchez Moreno, José; Vieta i Pascual, Eduard, 1963- (Publication date: 2026-02-23)

    In this viewpoint, we explore the evolving landscape of psychedelic-assisted therapy in Europe, focusing on clinical, regulatory, and therapeutic developments. While access remains limited, recent initiatives in Switzerland, ...