Articles publicats Departament de Biologia: Recent submissions
Now showing items 101-120 of 408
Healthy dietary pattern and their corresponding gut microbiota profile are linked to a lower risk of type 2 diabetes, independent of the presence of obesity
Background Prediabetes and old age are both high risk factors for developing Type 2 Diabetes (T2D), while obesity is one of the most important factors triggering the disease. Nutritional interventions are the most effective ...
Intracranial self-stimulation modulates levels of SIRT1 protein and neural plasticity-related microRNAs
Deep brain stimulation (DBS) of reward system brain areas, such as the medial forebrain bundle (MFB), by means of intracranial self-stimulation (ICSS), facilitates learning and memory in rodents. MFB-ICSS has been found ...
Novel Lines of Research on the Environmental and Human Health Impacts of Nut Consumption
Nuts have formed part of human diets throughout the ages. In recent decades, research has shown they are key foods in dietary patterns associated with lower chronic disease risk. The current state of climate change, however, ...
La recerca en biologia avui
Article dedicat a la recerca que es fa en el camp de la Biologia, en especial a la Universitat de Girona
Aquaglyceroporins but not orthodox aquaporins are involved in the cryotolerance of pig spermatozoa
Aquaporins (AQPs) are a family of transmembrane water channels that includes orthodox AQPs, aquaglyceroporins (GLPs) and superAQPs. AQP3, AQP7, AQP9 and AQP11 have been identified in boar sperm, and they are crucial for ...
Seminal extracellular vesicles subsets modulate gene expression in cumulus cells of porcine in vitro matured oocytes
Seminal plasma (SP), a fluid composed mainly by secretions from accessory sex glands, contains a heterogenous population of extracellular vesicles (EVs), involved in several reproductive physiological processes. Seminal ...
Development and characterization of novel microsatellites markers by next generation sequencing for the blue and red shrimp Aristeus antennatus.
The blue and red shrimp, Aristeus antennatus, is a commercially important crustacean, in the Mediterranean Sea, which has been listed as a priority species for fishery management. Hypervariable microsatellite markers could ...
Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality
The present study sought to determine the relationship of three sperm proteins (acrosin binding protein, ACRBP; outer dense fibre protein 1, ODF1; and triosephosphate isomerase, TPI), and two seminal plasma proteins ...
An integrin-targeted photoactivatable Pt(iv) complex as a selective anticancer pro-drug: Synthesis and photoactivation studies
A new anticancer agent based on the conjugation of a photoactivatable Pt(iv) pro-drug to a cyclic RGD-containing peptide is described. Upon visible light irradiation, phototoxicity was induced preferentially in SK-MEL-28 ...
Destabilizing Mutations Alter the Hydrogen Exchange Mechanism in Ribonuclease A
The effect of strongly destabilizing mutations, I106A and V108G of Ribonuclease A (RNase A), on its structure and stability has been determined by NMR. The solution structures of these variants are essentially equivalent ...
Filogènies moleculars i l’arbre de la vida: el concepte d'espècie
A la Terra hi ha una biodiversitat que va aparèixer al llarg de milions d’anys d’evolució. Els biòlegs ens interessem a conèixer les relacions entre els organismes i els seus orígens. No obstant això, no posseïm un coneixement ...
Biotecnologia reproductiva en porcí: estat actual i reptes de futur
Reproductive biotechnology in porcine includes several techniques of analysis of the seminal quality and techniques of assisted reproduction. The main goals are guaranteeing the biological security, allowing the traceability ...
A comparative study of the effects of Escherichia coli and Clostridium perfringens upon boar semen preserved in liquid storage
The present study compares the sperm quality of boar seminal doses artificially inoculated with Escherichia coli and Clostridium perfringens, and maintained in liquid storage at 15 °C for a 9-day period. Seminal doses from ...
Investigating the Effects of Double Mutation C30A/C75A on Onconase Structure: Studies at Atomic Resolution
The structure of onconase C30A/C75A double mutant has been determined at 1.12A° resolution. The structure has high structural homology to other onconase structures. The changes being results of mutation are relatively ...
Interferon/STAT1 and neuregulin signaling pathways are exploratory biomarkers of cetuximab (Erbitux®) efficacy in KRAS wild-type squamous carcinomas: A pathway-based analysis of whole human-genome microarray data from cetuximab-adapted tumor cell-line models
KRAS mutation status is being used as the sole biomarker to predict therapeutic efficacy of cetuximab in metastatic colorectal cancer (mCRC). A significant number of mCRC patients with KRAS wild-type (WT) tumors, however, ...
Population genetics meets phylogenetics: new insights into the relationships among members of the genus Euthynnus (family Scombridae)
Euthynnus (family Scombridae) is a genus of marine pelagic fish species with a worldwide distribution that comprises three allopatric species: E. alletteratus, E. affinis and E. lineatus. All of them targeted by artisanal ...
Seminal Plasma Modulates miRNA Expression by Sow Genital Tract Lining Explants
The seminal plasma (SP) modulates the female reproductive immune environment after mating, and microRNAs (miRNAs) could participate in the process. Considering that the boar ejaculate is built by fractions differing in ...
Advanced Sperm Selection Strategies as a Treatment for Infertile Couples: A Systematic Review
Assisted reproductive technology (ART) is an essential tool to overcome infertility, and is a worldwide disease that affects millions of couples at reproductive age. Sperm selection is a crucial step in ART treatment, as ...
Androgen-independent prostate cancer cells circumvent EGFR inhibition by overexpression of alternative HER receptors and ligands
The deregulation of the epidermal growth factor receptor (EGFR) pathway plays a major role in the pathogenesis of prostate cancer (PCa). However, therapies targeting EGFR have demonstrated limited effectiveness in PCa. A ...
Tuna Species Substitution in the Spanish Commercial Chain: A Knock-On Effect
Intentional mislabelling of seafood is a widespread problem, particularly with high-value species like tuna. In this study we examine tuna mislabelling, deliberate species substitution, types of substitution and its ...
