Recerca: articles, congressos, llibres: Recent submissions
Now showing items 1-20 of 20987
New insights into thiopurine toxicity: The contribution of rare XDH variants to myelotoxicity
Thiopurines (azathioprine and mercaptopurine) are immunosuppressant drugs widely used for the treatment of acute lymphocytic leukemia, organ transplantation and autoimmune diseases, including inflammatory bowel diseases. ...
Characterization of systemic oxidative stress in asthmatic adults compared to healthy controls and its association with the oxidative potential of particulate matter collected using personal samplers
Inflammatory cell activation in asthma may lead to reactive oxygen species (ROS) overproduction with an imbalance between oxidant levels and antioxidant capacity, called oxidative stress (OS). Since particulate matter (PM) ...
Management of urinary stones by experts in stone disease (ESD 2025)
The formation of kidney stones is a complex biologic process involving interactions among genetic, anatomic, dietary, and environmental factors. Traditional lithogenic models were based on urine supersaturation in relation ...
Quantitative characterization of the 3D self-organization of PDAC tumor spheroids reveals cell type and matrix dependence through advanced microscopy analysis
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant tumor-associated stroma composed from pancreatic stellate cells, which play a critical role in tumor progression. Developing accurate in vitro models ...
The long road: ethnoarchaeology, pastoralism and the reconfiguration of archaeological knowledge
This article addresses the transformative role of ethnoarchaeology in reshaping the study of pastoralism. Long marginalized by dominant scientific and political discourses, pastoralism is now increasingly seen as a ...
¿Cómo investiga la policía en España? Estudio exploratorio de su autonomía respecto del juez y el fiscal
A partir del análisis de cómo la policía española investiga y persigue los delitos, este estudio busca determinar el grado de autonomía que posee respecto al poder judicial. Para ello, además de examinar el marco normativo ...
Deep-time perspectives on drylands: archaeology as a lens for understanding long-term livelihood systems and resilience
Drylands are still widely perceived as marginal areas, unsuitable for food production and long-term human settlement. This view, reinforced by mainstream global land use models, stands in sharp contrast with archaeological ...
Colectomy and neoplasia outcomes of patients with ulcerative colitis receiving golimumab: A post-authorisation safety study using the spanish ENEIDA registry
Purpose: Golimumab (GLM), an anti-tumour necrosis factor alpha (anti-TNFa) agent, is indicated for moderate to severe ulcerative colitis (UC). This post-authorisation safety study evaluated the risk of colectomy due to ...
Enzalutamide plus radium-223 in metastatic castration-resistant prostate cancer: results of the EORTC 1333/PEACE-3 trial
Background: The EORTC 1333 'PEACE-3' study investigated the combination of enzalutamide and 6 monthly injections of radium-223 (Ra223) in patients with metastatic castration-resistant prostate cancer (mCRPC) and ...
Prevalence of EGFR gene mutations in patients with early-stage resectable non-small cell lung cancer in Spain: the ORIGEN study.
Background: Geographic variability in epidermal growth factor receptor (EGFR) mutation rates in early-stage non-small cell lung cancer (NSCLC) has been reported. However, the frequency of EGFR mutations in patients with ...
Staging laparoscopy in gastric cancer patients treated with curative intent: A European GASTRODATA cohort study
Background: In current guidelines, staging laparoscopy (SL) is recommended in patients with locally advanced gastric cancer (GC). This study aimed to assess the clinical practice of SL and its association with administration ...
On the geographic implications of carbon taxes
Data de publicació electrònica: 2025-04-15
Real-world evidence of Carfilzomib, Lenalidomide and Dexamethasone (KRD) Scheme in patients with relapsed / refractory multiple myeloma
Carfilzomib, lenalidomide and dexamethasone (KRd) is still a widely used treatment option for patients with relapsed / refractory multiple myeloma (RRMM). However, there is limited real-world evidence. Here we evaluated ...
Integration of optical genome mapping in the cytogenomic and molecular work-up of hematological malignancies: expert recommendations from the International Consortium for Optical Genome Mapping
The latest updates to the classification of hematolymphoid malignancies using the World Health Organization (WHO, 5th ed.) and ICC (International Consensus Classification) criteria highlight the critical need for comprehensive ...
Acute paraesophageal hernia with gastric volvulus. Results of surgical treatment: a systematic review and meta-analysis
Introduction: Acute gastric volvulus (AGV), is an uncommon complication of large paraesophageal hernias (PEH), resulting in closed-loop obstruction that may lead to incarceration and strangulation. The aim of this study ...
More person, and, therefore, more satisfied and happy: the affective economy of reading promotion in Chile
Reading is often regarded as a public good and an essential part of developing almost every aspect of human potential. In this article, we survey the "affective economies" of literary reading through a textual ...
Prognostic impact of positive peritoneal cytology (POPEC) in gastric cancer: Multi-centre European retrospective cohort study
Objective: Positive peritoneal cytology is traditionally viewed as representative of metastatic disease and a poor prognostic factor. The objective of this multi-center study was to define the prognostic role of peritoneal ...
Outcomes and predictors of mortality in patients with severe COVID-19 and COPD admitted to ICU: a multicenter study
Background: High mortality rates among patients with chronic obstructive pulmonary disease (COPD) admitted to intensive care units (ICUs) during the COVID-19 pandemic highlight the need for tailored clinical management ...
Broadening climate migration research across impacts, adaptation and mitigation
Current climate migration literature focuses on establishing links between climate drivers and migration. However, it often overlooks the broader role that migration plays within the context of climate impacts, adaptation ...
Natural history, immunological and genetic characteristics of preclinical inflammatory bowel disease (EARLY): study protocol for a prospective cohort study
Background: The period prior to the diagnosis of inflammatory bowel disease (IBD), defined as the preclinical phase, has emerged as a potential target for disease modification strategies. Despite the relevance of an early ...
