Title:
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Dual Catalytic Platform for Enabling sp3 α C−H Arylation and Alkylation of Benzamides
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Author:
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Rand, Alexander W.; Yin, Hongfei; Xu, Liang; Giacoboni, Jessica; Martin-Montero, Raul; Romano, Ciro; Montgomery, John; Martin, Ruben
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Abstract:
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A dual catalytic sp3 α C–H arylation and alkylation of benzamides with organic halides is described. This protocol exhibits an exquisite site selectivity, chemoselectivity, and enantioselectivity pattern, offering a complementary reactivity mode to existing sp3 arylation or alkylations via transition metal catalysis or photoredox events. |
Publication date:
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2020-03-27 |
Subject(s):
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54 |
Rights:
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L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Pages:
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4671 p. |
Document type:
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Article Article - Accepted version |
DOI:
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10.1021/acscatal.0c01318
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