Recent submissions

High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with treatment of physician’s choice—in the EMBRACE study

Miyoshi, Yasuo; Yoshimura, Yuta; Saito, Kenichi; Muramoto, Kenzo; Sugawara, Michiko; Alexis, Karenza; Cortés Castan, Javier (Publication date: 2021-09-16)

Eribulina; Càncer de mama metastàsic; Supervivència global

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023)

Navarro, Miguel; Porras, Ignacio; Hernando, Jorge; Maurente Oliveira, Eduardo; Jimenez Fonseca, Paula; Martinez-Trufero, Javier; Rubió-Casadevall, Jordi (Publication date: 2024-10-31)

Thyroid carcinoma; Molecular alterations; Systemic treatment

Pan-cancer whole-genome comparison of primary and metastatic solid tumours

Movasati, Ali; Brunner, Sascha Remy; Nguyen, Luan; Van Hoeck, Arne; Martínez-Jiménez, Francisco; Priestley, Peter; Cuppen, Edwin (Publication date: 2023-07-04)

Cancer genomics; DNA damage and repair; Metastasis

Towards evidence-based response criteria for cancer immunotherapy

Laurie, Scott; Seymour, Lesley; de Vries, Elisabeth; GARRALDA, Elena (Publication date: 2023-07-04)

Cáncer; Inmunología tumoral

A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer

Garralda Cabanas, Elena; Sukari, Ammar; Patnaik, Amita; Lou, Yanyan; Lakhani, Nehal; Im, Seock-Ah (Publication date: 2023-01-12)

Advanced; Colorectal cancer

AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers

Ruiz Ciancio, Dario; Veeramani, Suresh; Singh, Rahul; Embree, Eric; Ortman, Chris; Thiel, Kristina (Publication date: 2024-12-19)

Aptamer; Bioinformatics; Sequence analysis

Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases

Peters, Solange; Trigo, José; Besse, Benjamin; NAVARRO, ALEJANDRO; Moreno, Victor; Olmedo García, María Eugenia (Publication date: 2024-02-09)

Chemotherapy-free interval; Lurbinectedin; Response rate

Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment

Gulley, James; Schlom, Jeffrey; Barcellos-Hoff, Mary Helen; Wang, Xiao-Jing; Seoane, Joan; Audhuy, Francois (Publication date: 2023-05-23)

Immune checkpoint inhibitor; Tumor microenvironment

Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia

Errazquin, Ricardo; Page, Angustias; Suñol, Anna; Segrelles, Carmen; Carrasco Lopez, Estela; Peral, Jorge; Balmaña, Judith (Publication date: 2023-06-06)

Head and neck squamous cell carcinoma; Mouse model; Oral mucosa

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer

Harvey-Jones, Elizabeth J.; Raghunandan, Maya; Robbez-Masson, Luisa; Magraner-Pardo, Lorena; Alaguthurai, Thanu; Yablonovitch, Arielle; Balmaña, Judith; Serra, Violeta (Publication date: 2024-04-12)

PARP inhibitors; Breast cancer; Drug resistance

The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling

Plana-Carmona, Marcos; Stik, Grégoire; Bulteau, Romain; Segura Morales, Carolina; Alcazar Perez, Noelia; Wyatt, Chris; Tian, Tian V; Vila Casadesus, Maria (Publication date: 2022-12-12)

Gene regulation; Somatic cell reprogramming; Trophectoderm

Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer

Yndestad, Synnøve; Engebrethsen, Christina; Nikolaienko, Oleksii; Vintermyr, Olav Karsten; Lillestøl, Reidun; Llop-Guevara, Alba; Herencia Ropero, Andrea; Serra, Violeta (Publication date: 2024-01-09)

Homologous recombination; Primary breast cancer

AXL – a new player in resistance to HER2 blockade

Cejalvo, Juan Miguel; ADAM-ARTIGUES, ANNA; ARENAS LAHUERTA, ENRIQUE JAVIER; Arribas, Joaquin; Prat, Aleix (Publication date: 2023-11-08)

Cancer; HER2 disease; Resistance

GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis

Sánchez Maldonado, Jose Manuel; Cabrera Serrano, Antonio José; Chattopadhyay, Subhayan; CAMPA, DANIELE; Garrido , María del Pilar; Macauda, Angelica; Jerez, Andres (Publication date: 2023-05-05)

Genetic variants; Multiple myeloma; Obesity

Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 Study

Randon, Giovanni; Nakamura, Yoshiaki; CREMOLINI, CHIARA; Yaeger, Rona; Lonardi, Sara; Elez, Elena; Ros, Javier (Publication date: 2024-02-14)

Hyperselection; Metastatic colorectal cancer

Endocrine and Neuroendocrine Tumors Special Issue—Checkpoint Inhibitors for Adrenocortical Carcinoma and Metastatic Pheochromocytoma and Paraganglioma: Do They Work?

Jimenez, Camilo; Armaiz-Pena, Gustavo; Dahia, Patricia; Lu, Yang; De Almeida Toledo, Rodrigo; Varghese, Jeena; Habra, Mouhammed Amir (Publication date: 2023-01-10)

Adrenocortical cancer; Checkpoint inhibitors; Metastatic paraganglioma

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy

Appierto, Valentina; Silvestri, Marco; Baselga Torres, Jose Manuel; Piccart, Martine; Nuciforo, Paolo Giovanni; Di Cosimo, Serena; Pizzamiglio, Sara (Publication date: 2021-09-01)

Càncer de mama; MicroRNA circulants; Trastuzumab

ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer

Estévez-García, Purificación; Martin Martorell, Paloma; Sais, Elia; Bosch-Barrera, Joaquim; Sabatier, Renaud; Nadal, Ernest; OAKNIN, ANA (Publication date: 2025-04-04)

Advanced squamous non-small cell lung cancer; Autophagy; Chemotherapy

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

van Schooten, Tessa Suzanne; Derks, Sarah; Jiménez-Martí, Elena; Carneiro, Fatima; Ruiz-Garcia, Erika; Alsina, Maria; Molero, Cristina; Figueiredo, Ceu (Publication date: 2023-06-07)

Gastric cancer; Tumor microenvironment; Prevention

MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer

Dinami, Roberto; Pompili, Luca; Petti, Eleonora; Porru, Manuela; D’Angelo, Carmen; Di Vito, Serena; Serra Elizalde, Violeta (Publication date: 2023-04-24)

Target therapy; Telomeres; Triple-negative breast cancer

Articles científics - VHIO: Recent submissions

High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with treatment of physician’s choice—in the EMBRACE study ﻿

SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023) ﻿

Pan-cancer whole-genome comparison of primary and metastatic solid tumours ﻿

Towards evidence-based response criteria for cancer immunotherapy ﻿

A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer ﻿

AptamerRunner: An accessible aptamer structure prediction and clustering algorithm for visualization of selected aptamers ﻿

Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases ﻿

Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment ﻿

Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia ﻿

Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer ﻿

The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling ﻿

Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer ﻿

AXL – a new player in resistance to HER2 blockade ﻿

GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis ﻿

Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 Study ﻿

Endocrine and Neuroendocrine Tumors Special Issue—Checkpoint Inhibitors for Adrenocortical Carcinoma and Metastatic Pheochromocytoma and Paraganglioma: Do They Work? ﻿

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy ﻿

ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer ﻿

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally ﻿

MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer ﻿