Enviaments recents

Metastatic hormone-naïve prostate cancer: a distinct biological entity

Corres-Mendizabal, Jon; Martín-Martín, Natalia; Carracedo, Arkaitz; Zacchi, Francesca; Mateo, Joaquin (Data de publicació: 2024-09-25)

Models experimentals; Metàstasi; Càncer de pròstata

Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS)

Pantel, Klaus; Alix-Panabières, Prof Catherine; Hofman, P.; Stoecklein, Nikolas Hendrik; Lu, Yong-Jie; Lianidou, Evi; Toledo, Rodrigo (Data de publicació: 2025-08-12)

Liquid biopsy; European liquid biopsy society

Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and –independent regulatory pathways

Martínez-Torró, Carlos; Torres-Puig, Sergi; Monge Azemar, Marta; Sánchez-Alba, Lucía; González-Martín, Miguel; Marcos-Silva, Marina; Canals Suris, Francesc (Data de publicació: 2021-09-09)

Regulador d'absorció fèrric; Mycoplasma genitalium; Patogen emergent d'ITS

Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis

González-Martínez, Silvia; Pizarro, David; Pérez-Mies, Belén; Caniego-Casas, Tamara; Cortés Castan, Javier; Palacios, José; Curigliano, Giuseppe (Data de publicació: 2022-06-07)

Breast cancer; Metastasis; Skin

TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains

Guerrero-Martínez, Jose A.; Ceballos-Chávez, María; Koehler, Florian; Peiro Sales, Sandra; Reyes, Jose C. (Data de publicació: 2021-09-03)

Cromatina; Informàtica del genoma; Transcripció

Young-onset biliary tract cancers: Characteristics, treatment patterns, and patient outcomes

Pudlarz, Thomas; Hilmi, Marc; Antoun, Leony; Turpin, Anthony; Tissera, Natalia Soledad; Castet, Florian; López-Valbuena, Daniel; García-Galea, Eduardo; Castillo, Gloria; TIAN, TIAN; Macarulla, Teresa (Data de publicació: 2025-10-22)

Young-onset; Biliary tract cancers; Cholangiocarcinoma

Associations of Tissue Tumor Mutational Burden and Mutational Status With Clinical Outcomes With Pembrolizumab Plus Chemotherapy Versus Chemotherapy For Metastatic NSCLC

Garassino, Marina Chiara; Novello, S.; Halmos, Balazs; Speranza, Giovanna; Gadgeel, Shirish; Felip Font, Enriqueta (Data de publicació: 2023-03-09)

Biomarker; Pembrolizumab; Tissue tumor mutational burden

A first-in-human phase I study of the PD-1 inhibitor, retifanlimab (INCMGA00012), in patients with advanced solid tumors (POD1UM-101)

Lakhani, Nehal; Cosman, Rasha; Banerji, Udai; Rasco, D.; Tomaszewska-Kiecana, Monika; GARRALDA, Elena (Data de publicació: 2024-02-26)

Inhibidores de puntos de control; Retifanlimab; Tumor sólido

Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164

Le, Dung T.; Van Cutsem, Eric; Geva, Ravit; Jäger, Dirk; Hara, Hiroki; Elez Fernandez, Mª Elena; Kim, Tae Won (Data de publicació: 2021-08-23)

Pembrolizumab; Càncer colorectal

Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Review and New Horizons Toward Personalised Medicine

Alpuim Costa, Diogo; Nobre, José Guilherme; Ribeiro, Catarina; Calle, Catarina; Cortés, A.; Cortés Castan, Javier; Vaz Batista, Marta (Data de publicació: 2022-06-08)

Breast cancer; Personalized medicine; Pharmacomicrobiomics

BRCA2 and Other DDR Genes in Prostate Cancer

Nombela, Paz; Lozano, Rebeca; Aytes, Alvaro; Mateo Valderrama, Joaquim; Olmos, David; Castro, Elena (Data de publicació: 2019-05-20)

BRCA2; DDR; Prostate cancer

Obesity and Breast Cancer: A Paradoxical and Controversial Relationship Influenced by Menopausal Status

García-Estévez, Laura; Cortés Castan, Javier; Pérez, Silvia; Calvo, Isabel; Gallegos, Isabel; Moreno-Bueno, Gema (Data de publicació: 2022-02-01)

Mamografia; Menopausa; Obesitat

Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites

Sabarinathan, Radhakrishnan; Lopez-Bigas, Nuria; Frigola Rissech, Joan; Gonzalez-Perez, Abel (Data de publicació: 2021-06-29)

Llocs d’unió; Dany en l'ADN; Factor de transcripció

Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer

Dhital, Brittiny; Santasusagna Canal, Sandra; Kirthika, Perumalraja; Xu, Michael; Li, Peiyao; Carceles-Cordon, Marc; Malumbres Martinez, Marcos (Data de publicació: 2023-03-09)

Chromosomal instability; Lethal prostate cancer; Therapy resistance

FAIM-L - SIVA-1: Two Modulators of XIAP in Non-Apoptotic Caspase Function

Coccia, Elena; Sole Piñol, Montse; Comella, Joan X (Data de publicació: 2023-01-09)

Alzheimer's disease; Axon remodeling; Synaptic plasticity

Safety and activity of anti-mesothelin antibody–drug conjugate anetumab ravtansine in combination with pegylated-liposomal doxorubicin in platinum-resistant ovarian cancer: multicenter, phase Ib dose escalation and expansion study

Santin, Alessandro; González-Martin, Antonio; Moore, Kathleen N; Oaknin Benzaquen, Ana Mazaltob; Romero, Ignacio; Vergote, Ignace (Data de publicació: 2023-04-20)

Ovarian cancer

NEDDylation Regulates CD8+ T-cell Metabolism and Antitumor Immunity

Jimenez, Borja; Perez-Gutierrez, Lorena; Lee, So Young; de Blas, Ander; Velasco-Beltrán, Paloma; Egia-Mendikute, Leire; Prieto-Fernández, Endika (Data de publicació: 2025-09-02)

NEDDylation; Metabolism; Antitumor immunity

Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial

Fizazi, Karim; Saad, Fred; de Bono, Johann S; Shore, Neal; Sandhu, Shahneen; Mateo, Joaquin (Data de publicació: 2024-02-13)

Olaparib; Castration-resistant prostate cancer

GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program

Lewis, Michael; Terre Torras, Berta; Knobel, Philip; Cheng, Tao; Lu, Hao; Querol Paños, Jessica; Stephan-Otto Attolini, Camille (Data de publicació: 2023-04-04)

Cell signalling; Transcription

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

Chondronasiou, Dafni; Gill, Diljeet; Mosteiro, Lluc; Urdinguio, Rocio G; Berenguer-LLergo, Antoni; Aguilera Pujabet, Mònica; Abad Mendez, Maria (Data de publicació: 2022-07-21)

Aging; Epigenetic clocks; Pluripotency

Articles científics - VHIO: Enviaments recents

Metastatic hormone-naïve prostate cancer: a distinct biological entity ﻿

Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS) ﻿

Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and –independent regulatory pathways ﻿

Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis ﻿

TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains ﻿

Young-onset biliary tract cancers: Characteristics, treatment patterns, and patient outcomes ﻿

Associations of Tissue Tumor Mutational Burden and Mutational Status With Clinical Outcomes With Pembrolizumab Plus Chemotherapy Versus Chemotherapy For Metastatic NSCLC ﻿

A first-in-human phase I study of the PD-1 inhibitor, retifanlimab (INCMGA00012), in patients with advanced solid tumors (POD1UM-101) ﻿

Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164 ﻿

Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Review and New Horizons Toward Personalised Medicine ﻿

BRCA2 and Other DDR Genes in Prostate Cancer ﻿

Obesity and Breast Cancer: A Paradoxical and Controversial Relationship Influenced by Menopausal Status ﻿

Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites ﻿

Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer ﻿

FAIM-L - SIVA-1: Two Modulators of XIAP in Non-Apoptotic Caspase Function ﻿

Safety and activity of anti-mesothelin antibody–drug conjugate anetumab ravtansine in combination with pegylated-liposomal doxorubicin in platinum-resistant ovarian cancer: multicenter, phase Ib dose escalation and expansion study ﻿

NEDDylation Regulates CD8+ T-cell Metabolism and Antitumor Immunity ﻿

Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial ﻿

GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program ﻿

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming ﻿