Recent submissions

Thrombosis and Hyperinflammation in COVID-19 Acute Phase Are Related to Anti-Phosphatidylserine and Anti-Phosphatidylinositol Antibody Positivity

Anunciación-Llunell, Ariadna; Morales-Pérez, Stephanie; Trape, Jaume; Esteve-Valverde, Enrique; Miro-Mur, Francesc A.; Alijotas-Reig, Jaume (Publication date: 2023-09-01)

COVID-19; Antiphospholipid antibodies; Thrombosis

Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response

Delavy, Margot; Sertour, Natacha; Patin, Etienne; LE CHATELIER, Emmanuelle; Cole, Nathaniel; Dubois, Florian; Chaysavanh, Manichanh (Publication date: 2024-01-15)

Candida albicans; Colonization resistance; Metagenomics

Prevention of Stroke in Intracerebral Haemorrhage Survivors with Atrial Fibrillation: Rationale and Design for PRESTIGE-AF Trial

Heuschmann, Peter; Fiessler, Cornelia; Malzahn, Uwe; Hügen, Klemens; Montaner Villalonga, Joan; Korompoki, Eleni; Harvey, Kirsten (Publication date: 2025-04-14)

Prevention of stroke; Intracerebral haemorrhage; Atrial fibrillation

Usefulness of Eye Fixation Assessment for Identifying Type 2 Diabetic Subjects at Risk of Dementia

Simó Servat, Olga; Ortiz Zuñiga, Angel Michael; Hernández Pascual, Cristina; Simó Canonge, Rafael; Ciudin Mihai, Andreea (Publication date: 2019-02-14)

Dementia; Diabetes; Microperimetry

Endometrial cancer PDX-derived organoids (PDXOs) and PDXs with FGFR2c isoform expression are sensitive to FGFR inhibition

Sengal, Asmerom; Bonazzi, Vanessa; Smith, Deborah S; Lourie, Rohan; Rogers, Rebecca; Colás Ortega, Eva; Gil-Moreno, Antonio; Moiola, Cristian Pablo (Publication date: 2024-01-08)

Endometrial cancer; Immunohistochemistry; Predictive markers

Preclinical Development of a Therapy for Chronic Traumatic Spinal Cord Injury in Rats Using Human Wharton’s Jelly Mesenchymal Stromal Cells: Proof of Concept and Regulatory Compliance

Vives Armengol, Joaquim; Hernandez, Joaquim; Clementine, Mirabel; Puigdomenech-Poch, Maria; Romeo-Guitart, David; Marmolejo Martínez-Artesero, Sara; Cabrera Perez, Raquel (Publication date: 2022-10-11)

Animal model; Cell therapy; Mesenchymal stromal cells

Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project

Blot, Stijn; Blot, Koen; Creagh-Brown, Ben; Rello Condomines, Jordi; Antonelli, Massimo; Arvaniti, Kostoula; de Lange, Dylan (Publication date: 2020-09-02)

Intra-abdominal infection; Peritonitis; Sepsis

Transcriptomic Analysis Reveals That Retinal Neuromodulation Is a Relevant Mechanism in the Neuroprotective Effect of Sitagliptin in an Experimental Model of Diabetic Retinopathy

Ramos Abellan, Hugo; Bogdanov Baruj, Patricia; Deàs Just, Anna; Hernández Buñuel, Cristina; Simó Canonge, Rafael (Publication date: 2023-02-24)

Diabetic retinopathy; Sitagliptin; Synaptic signal transmission

Modeling Functional Limitations, Gait Impairments, and Muscle Pathology in Alzheimer’s Disease: Studies in the 3xTg-AD Mice

Castillo-Mariqueo, Lidia; Pérez García, Maria Jose; Giménez-Llort, Lydia (Publication date: 2022-05-18)

Frailty; Muscular strength; Translational neuroscience

Transplantation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium in a Swine Model of Geographic Atrophy

Duarri Piqué, Anna; Rodríguez-Bocanegra, Eduardo; Martínez-Navarrete, Gema; García, Miriam; Ferraro, Lucía Lee; Biarnés, Marc (Publication date: 2022-05-02)

Modelo animal; Medicina regenerativa; Retina

The histone demethylase PHF8 regulates astrocyte differentiation and function

Padilla Sirera, Natalia; Gabrielli, Martina; Navarro, Claudia; Lombardi, Marta; Vicioso Mantis, Marta; De la Cruz Montserrat, Fco. Xavier; Iacobucci, Simona (Publication date: 2022-07-18)

Astrocyte differentiation; Chromatin transcription; Synapse

Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes

Aterido Ballonga, Adria; Lopez Lasanta, Maria America; Blanco, Francisco; Juan-Mas, Antonio; García-Vivar, María Luz; Erra Duran, ALBA; Palau Balaña, Nuria; marsal, sara; Julià Cano, Antonio (Publication date: 2024-03-18)

Immune receptor; Rheumatoid arthritis; Phenotypes

First prospective, single-arm, multicenter study to evaluate safety and efficacy of the overall thrombectomy system -iNedit, iNdeep, and iNtercept- for acute ischemic stroke. Rationale beyond the study

San Román, Luis; Pich, Sara; Domingo Rodriguez, Laura; Duran, Marta; Duocastella, Lluís; Gramegna, Laura Ludovica (Publication date: 2025-10-22)

Acute ischemic stroke; Balloon guide catheter; Distal aspiration catheter

Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

Gracia-Diaz, Carolina; Zhou, Yijing; Yang, Qian; España, Paula; Lee, Chul-Hwan; Padilla Sirera, Natàlia; Maroofian, Reza (Publication date: 2023-08-22)

Autism spectrum disorders

Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents

Pavlova, Julia A.; Khairullina, Zimfira Z.; Tereshchenkov, Andrey G.; Nazarov, Pavel A.; Lukianov, Dmitrii A.; Volynkina, Inna A.; Lyakhovich, Alex (Publication date: 2022-01-14)

Activitat antibiòtica; Ribosoma bacterià; Simulacions de dinàmica molecular

Evolution of the Early Spliceosomal Complex—From Constitutive to Regulated Splicing

Borao Arriazu, Sonia; Ayte, Jose; Hümmer, Stefan (Publication date: 2022-05-25)

Unión exón-intrón; Espliceosoma; Empalme

Diagnostic and prognostic prediction models in ventilator-associated pneumonia: Systematic review and meta-analysis of prediction modelling studies

Atkova, Irina; Rello Condomines, Jordi; Miettunen, Jouko; Jansson, Miia; Frondelius, Tuomas (Publication date: 2022-07-22)

Machine learning; Mechanical ventilation; Prognostic model

Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life

van Tol, Lisa; Haaksma, Miriam; Cesari, Matteo; Everink, Irma; Francis, Bahaa N; Pérez, Laura Mónica; Dockery, Frances (Publication date: 2024-05-16)

COVID-19; Geriatric rehabilitation; Older people

Respiratory dysbiosis as prognostic biomarker of disease severity for adults with community-acquired pneumonia requiring mechanical ventilation

Vidaur, Loreto; Guridi, Amalur; Leizaola, Oihana; Marin, Jokin; Rello, Jordi; Sarasqueta, Cristina (Publication date: 2025-06-16)

Biomarkers; Lung microbiome; Severe community-acquired pneumonia

Delirium prevalence and delirium literacy across Italian hospital wards: a secondary analysis of data from the World Delirium Awareness Day 2023

Okoye, Chukwuma; Mazzola, Paolo; Finazzi, Alberto; Ornago, Alice Margherita; Pinardi, Elena; Ferrara, Maria Cristina; Morandi, Alessandro (Publication date: 2024-12-19)

Delirium; Hospital; Survey

Vall d'Hebron Institut de Recerca – VHIR: Recent submissions

Thrombosis and Hyperinflammation in COVID-19 Acute Phase Are Related to Anti-Phosphatidylserine and Anti-Phosphatidylinositol Antibody Positivity ﻿

Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response ﻿

Prevention of Stroke in Intracerebral Haemorrhage Survivors with Atrial Fibrillation: Rationale and Design for PRESTIGE-AF Trial ﻿

Usefulness of Eye Fixation Assessment for Identifying Type 2 Diabetic Subjects at Risk of Dementia ﻿

Endometrial cancer PDX-derived organoids (PDXOs) and PDXs with FGFR2c isoform expression are sensitive to FGFR inhibition ﻿

Preclinical Development of a Therapy for Chronic Traumatic Spinal Cord Injury in Rats Using Human Wharton’s Jelly Mesenchymal Stromal Cells: Proof of Concept and Regulatory Compliance ﻿

Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project ﻿

Transcriptomic Analysis Reveals That Retinal Neuromodulation Is a Relevant Mechanism in the Neuroprotective Effect of Sitagliptin in an Experimental Model of Diabetic Retinopathy ﻿

Modeling Functional Limitations, Gait Impairments, and Muscle Pathology in Alzheimer’s Disease: Studies in the 3xTg-AD Mice ﻿

Transplantation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium in a Swine Model of Geographic Atrophy ﻿

The histone demethylase PHF8 regulates astrocyte differentiation and function ﻿

Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes ﻿

First prospective, single-arm, multicenter study to evaluate safety and efficacy of the overall thrombectomy system -iNedit, iNdeep, and iNtercept- for acute ischemic stroke. Rationale beyond the study ﻿

Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders ﻿

Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents ﻿

Evolution of the Early Spliceosomal Complex—From Constitutive to Regulated Splicing ﻿

Diagnostic and prognostic prediction models in ventilator-associated pneumonia: Systematic review and meta-analysis of prediction modelling studies ﻿

Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life ﻿

Respiratory dysbiosis as prognostic biomarker of disease severity for adults with community-acquired pneumonia requiring mechanical ventilation ﻿

Delirium prevalence and delirium literacy across Italian hospital wards: a secondary analysis of data from the World Delirium Awareness Day 2023 ﻿