The subsistence of Neolithic populations is based on agriculture, whereas that of previous populations was based on hunting and gathering. Neolithic spreads due to dispersal of populations are called demic, and those due to the incorporation of hunter-gatherers are called cultural. It is well-known that, after agriculture appeared in West Africa, it spread across most of subequatorial Africa. It has been proposed that this spread took place alongside with that of Bantu languages. In eastern and southeastern Africa, it is also linked to the Early Iron Age. From the beginning of the last millennium BC, cereal agriculture spread rapidly from the Great Lakes area eastwards to the East African coast, and southwards to northeastern South Africa. Here we show that the southwards spread took place substantially more rapidly (1.50–2.27 km/y) than the eastwards spread (0.59–1.27 km/y). Such a faster southwards spread could be the result of a stronger cultural effect. To assess this possibility, we compare these observed ranges to those obtained from a demic-cultural wave-of-advance model. We find that both spreads were driven by demic diffusion, in agreement with most archaeological, linguistic and genetic results. Nonetheless, the southwards spread seems to have indeed a stronger cultural component, which could lead support to the hypothesis that, at the southern areas, the interaction with pastoralist people may have played a significant role