Título:
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A heterogeneous single-atom palladium catalyst surpassing homogeneous systems for Suzuki coupling
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Autor/a:
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Chen, Zupeng; Vorobyeva, Evgeniya; Mitchell, Sharon; Fako, Edvin; Ortuño, Manuel A.; López, Núria; Collins, Sean M.; Midgley, Paul A.; Richard, Sylvia; Vilé, Gianvito; Pérez-Ramírez, Javier
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Abstract:
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Palladium-catalysed cross-coupling reactions, central tools
in fine-chemical synthesis, predominantly employ soluble
metal complexes despite recognized challenges with product
purification and catalyst reusability1– 3. Attempts to
tether these homogeneous catalysts on insoluble carriers
have been thwarted by suboptimal stability, which leads to a
progressively worsening performance due to metal leaching
or clustering4. The alternative application of supported Pd
nanoparticles has faced limitations because of insufficient
activity under the mild conditions required to avoid thermal
degradation of the substrates or products. Single-atom heterogeneous
catalysts lie at the frontier5–18. Here, we show
that the Pd atoms anchored on exfoliated graphitic carbon
nitride (Pd-ECN) capture the advantages of both worlds, as
they comprise a solid catalyst that matches the high chemoselectivity
and broad functional group tolerance of stateof-
the-art homogeneous catalysts for Suzuki couplings, and
also demonstrate a robust stability in flow. The adaptive
coordination environment within the macroheterocycles of
ECN facilitates each catalytic step. The findings illustrate the
exciting opportunities presented by nanostructuring single
atoms in solid hosts for catalytic processes that remain difficult
to heterogenize. |
Fecha de creación:
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25-06-2018 |
Materia(s):
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54 |
Derechos:
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L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Páginas:
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702 p. |
Tipo de documento:
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Artículo Artículo - Versión aceptada |
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