Título:
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Associations between DSM-IV mental disorders and subsequent COPD diagnosis
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Autor/a:
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Rapsey, Charlene M.; Lim, Carmen; Al-Hamzawi, Ali; Alonso Caballero, Jordi; Bruffaerts, Ronny; Caldas de Almeida, José Miguel; Florescu, Silvia; Girolamo, Giovanni de; Hu, Chiyi; Kessler, Ronald C.; Kovess, Viviane; Levinson, Daphna; Medina Mora, Maria Elena; Murphy, Sam; Ono, Yutaka; Piazza, Marina; Posada Villa, José; Have, Margeet ten; Wojtyniak, Bogdan J.; Scott, Kate M.
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Abstract:
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OBJECTIVES: COPD and mental disorder comorbidity is commonly reported, although findings are limited by substantive weaknesses. Moreover, few studies investigate mental disorder as a risk for COPD onset. This research aims to investigate associations between current (12-month) DSM-IV mental disorders and COPD, associations between temporally prior mental disorders and subsequent COPD diagnosis, and cumulative effect of multiple mental disorders. METHODS:
Data were collected using population surveys of 19 countries (n=52,095). COPD diagnosis was assessed by self-report of physician's diagnosis. The World Mental Health-Composite International Diagnostic Interview (WMH-CIDI) was used to retrospectively assess lifetime prevalence and age at onset of 16 DSM-IV disorders. Adjusting for age, gender, smoking, education, and country, survival analysis estimated associations between first onset of mental disorder and subsequent COPD diagnosis. RESULTS: COPD and several mental disorders were concurrently associated across the 12-month period (ORs 1.5-3.8). When examining associations between temporally prior disorders and COPD, all but two mental disorders were associated with COPD diagnosis (ORs 1.7-3.5). After comorbidity adjustment, depression, generalized anxiety disorder, and alcohol abuse were significantly associated with COPD (ORs 1.6-1.8). There was a substantive cumulative risk of COPD diagnosis following multiple mental disorders experienced over the lifetime. CONCLUSIONS:
Mental disorder prevalence is higher in those with COPD than those without COPD. Over time, mental disorders are associated with subsequent diagnosis of COPD; further, the risk is cumulative for multiple diagnoses. Attention should be given to the role of mental disorders in the pathogenesis of COPD using prospective study designs. |
Abstract:
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The World Health Organization World Mental Health (WMH) Survey Initiative is supported by the National Institute of Mental Health (NIMH; R01 MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the US Public Health Service (R13- MH066849, R01-MH069864, and R01 DA016558) and the Fogarty International Center (FIRCA R03-TW006481). The ESEMeD project is funded by the European Commission (Contracts QLG5-1999-01042; SANCO 2004123, and EAHC 20081308), the Piedmont Region (Italy)), Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spain (FIS 00/0028), Ministerio de Ciencia y Tecnología, Spain (SAF 2000- 158-CE), Departament de Salut, Generalitat de Catalunya, Spain and the Instituto de Salud Carlos III (CIBER CB06/02/0046, RETICS RD06/0011 REM-TAP), Spain |
Materia(s):
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-Malalties mentals -Pulmons -- Malalties obstructives |
Derechos:
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© Elsevier http://dx.doi.org/10.1016/j.jpsychores.2015.08.005 |
Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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Elsevier
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