Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination

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Utilizad este identificador para citar o enlazar este documento: http://hdl.handle.net/2072/335518

Título:	Ruthenium-Catalyzed Peri- and Ortho-Alkynylation with Bromoalkynes via Insertion and Elimination
Autor/a:	Tan, Eric; Konovalov, Andrey I.; Dorel, Ruth; Fernández, Gabriela A.; Echavarren, Antonio M.
Abstract:	The alkynylation of naphthols takes place with total regiocontrol at the peri position of the hydroxyl group in the presence of [RuCl2(p-cymene)]2 as the catalyst. This reaction features high functional group tolerance. The related ortho- alkynylation of benzoic acids proceeds under similar conditions and also shows wide functional group tolerance. Both reactions proceed through metalation, insertion of the alkyne, and bromide elimination.
Fecha de creación:	04-10-2017
Materia(s):	54
Derechos:	L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/
Páginas:	5561 p.
Tipo de documento:	Artículo Artículo - Versión aceptada
DOI:	10.1021/acs.orglett.7b02655
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Muratore, Michael E.; Konovalov, Andrey I.; Armengol-Relats, Helena; Echavarren, Antonio M.

García-Morales, Cristina; Ranieri, Beatrice; Escofet, Imma; Loṕez-Suarez, Laura; Obradors, Carla; Konovalov, Andrey I.; Echavarren, Antonio M.

Tan, Eric; Quinonero, Ophélie; de Orbe, M. Elena; Echavarren, Antonio M.

Tan, Eric; Zanini, Margherita; Echavarren, Antonio M.

Della-Felice, Franco; Zanini, Margherita; Jie, Xiaoming; Tan, Eric; Echavarren, Antonio M.

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