dc.contributor
Institut Català de la Salut
dc.contributor
[González-Martínez S] Clinical Researcher, Hospital Ramón y Cajal, Madrid, Spain. Fundación Contigo contra el Cáncer de la Mujer, Madrid, Spain. [Pizarro D, Caniego-Casas T] Department of Pathology, Hospital Ramón y Cajal, Madrid, Spain. [Pérez-Mies B, Palacios J] Department of Pathology, Hospital Ramón y Cajal, Madrid, Spain. Institute Ramón y Cajal for Health Research (IRYCIS), Madrid, Spain. CIBER-ONC, Instituto de Salud Carlos III, Madrid, Spain. Faculty of Medicine, University of Alcalá de Henares, Alcalá de Henares, Madrid, Spain. [Curigliano G] European Institute of Oncology, IRCCS, Milan, Italy. Departament of Oncology and Hematology, University of Milan, Milan, Italy. [Cortés J] CIBER-ONC, Instituto de Salud Carlos III, Madrid, Spain. Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain. Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain. International Breast Cancer Center (IBCC), Quironsalud Group, Barcelona, Spain. Medica Scientia Innovation Research, Barcelona, Spain. Medica Scientia Innovation Research, Ridgewood, NJ, USA. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
González-Martínez, Silvia
dc.contributor.author
Pizarro, David
dc.contributor.author
Pérez-Mies, Belén
dc.contributor.author
Caniego-Casas, Tamara
dc.contributor.author
Cortés Castan, Javier
dc.contributor.author
Palacios, José
dc.contributor.author
Curigliano, Giuseppe
dc.date.accessioned
2025-10-25T05:39:40Z
dc.date.available
2025-10-25T05:39:40Z
dc.date.issued
2022-06-07T07:58:39Z
dc.date.issued
2022-06-07T07:58:39Z
dc.date.issued
2021-10-28
dc.identifier
González-Martínez S, Pizarro D, Pérez-Mies B, Caniego-Casas T, Curigliano G, Cortés J, et al. Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis. Cancers. 2021 Oct 28;13(21):5416.
dc.identifier
https://hdl.handle.net/11351/7630
dc.identifier
10.3390/cancers13215416
dc.identifier
000719073300001
dc.identifier.uri
http://hdl.handle.net/11351/7630
dc.description.abstract
Breast cancer; Metastasis; Skin
dc.description.abstract
Cáncer de mama; Metástasis; Piel
dc.description.abstract
Càncer de mama; Metàstasi; Pell
dc.description.abstract
Cutaneous metastases (CMs) account for 2% of all skin malignancies, and nearly 70% of CMs in women originate from breast cancer (BC). CMs are usually associated with poor prognosis, are difficult to treat, and can pose diagnostic problems, such as in histopathological diagnosis when occurring long after development of the primary tumor. In addition, the molecular differences between the primary tumors and their CMs, and between CMs and metastases in other organs, are not well defined. Here, we review the main clinical, pathological, and molecular characteristics of breast cancer CMs. Identifying molecular markers in primary BC that predict CM and can be used to determine the molecular differences between primary tumors and their metastases is of great interest for the design of new therapeutic approaches.
dc.description.abstract
This review was funded by grants from the Instituto de Salud Carlos III (ISCIII) (PI19/01331) and CIBERONC (CB16/12/00316 and CB16/12/00449), co-financed by the European Development Regional Fund, ‘A way to achieve Europe’ (FEDER), and by the Spanish Association Against Cancer Scientific Foundation (Grupos Coordinados Traslacionales aecc 2018).
dc.format
application/pdf
dc.relation
Cancers;13(21)
dc.relation
https://doi.org/10.3390/cancers13215416
dc.relation
info:eu-repo/grantAgreement/ES/PE2013-2016/CB16%2F12%2F00449
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Mama - Càncer - Prognosis
dc.subject
Cèl·lules canceroses - Proliferació
dc.subject
DISEASES::Neoplasms::Neoplasms by Site::Breast Neoplasms
dc.subject
DISEASES::Neoplasms::Neoplastic Processes::Neoplasm Metastasis
dc.subject
Other subheadings::Other subheadings::Other subheadings::/pathology
dc.subject
ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de la mama
dc.subject
ENFERMEDADES::neoplasias::procesos neoplásicos::metástasis neoplásica
dc.subject
Otros calificadores::Otros calificadores::Otros calificadores::/patología
dc.title
Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
