Sistema de Salut de Catalunya
Institut Català de la Salut
[Massimi L] Pediatric Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy. [Peretta P] Pediatric Neurosurgery, AOU Citta’ della Salute e della Scienza di Torino, Torino, Italy. [Erbetta A] Department of Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. [Solari A, Farinotti M] Neuroepidemiology Unit – Scientific Directorate, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. [Ciaramitaro P] Department of Neuroscience, AOU Citta’ della Salute e della Scienza di Torino, Torino, Italy. [Poca MA, Sahuquillo J] Unitat de Recerca en Neurotrauma i Neurocirurgia, Servei de Neurocirurgia i Neurocirurgia Pediàtrica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain
Vall d'Hebron Barcelona Hospital Campus
2022-02-22T07:45:30Z
2022-02-22T07:45:30Z
2021
2022-02
Malformació de Chiari 1; Nens; Siringomielia
Malformación de Chiari 1; Niños; Siringomielia
Chiari 1 malformation; Children; Syringomyelia
Background Chiari malformation type 1 (CM1) is a rare condition where agreed classification and treatment are still missing. The goal of this study is to achieve a consensus on the diagnosis and treatment of CM1 in children. Methods A multidisciplinary panel formulated 57 provisional statements based on a review of the literature. Thirty-four international experts (IE) participated in a Delphi study by independently rating each statement on a 4-point Likert scale (“strongly disagree,” “disagree,” “agree,” “strongly agree”). Statements that were endorsed (“agree” or “strongly agree”) by < 75% of raters were re-formulated, or new statements were added, and another Delphi round followed (up to a maximum of three). Results Thirty-five IE were contacted and 34 agreed to participate. A consensus was reached on 30/57 statements (52.6%) after round 1. Three statements were added, and one removed. After round 2, agreement was reached on 56/59 statements (94.9%). Finally, after round 3, which took place during the 2019 Chiari Consensus Conference (Milan, Italy), agreement was reached on 58/59 statements (98.3%) about four main sections (Definition and Classification, Planning, Surgery, Isolated Syringomyelia). Only one statement did not gain a consensus, which is the “definition of radiological failure 24 month post-surgery.” Conclusions The consensus document consists of 58 statements (24 on diagnosis, 34 on treatment), serving clinicians and researchers following children with CM1. There is a clear need for establishing an international network and registry and to promote collaborative studies to increase the evidence base and optimize the long-term care of this patient population.
Open access funding provided by Università Cattolica del Sacro Cuore within the CRUI-CARE Agreement.
Article
Published version
English
Tub neural - Malformacions; Malalties - Presa de decisions; Diagnòstic; INFORMATION SCIENCE::Information Science::Systems Analysis::Delphi Technique; NAMED GROUPS::Persons::Age Groups::Child; DISEASES::Nervous System Diseases::Nervous System Malformations::Neural Tube Defects::Arnold-Chiari Malformation; Other subheadings::Other subheadings::/therapy; CIENCIA DE LA INFORMACIÓN::Ciencias de la información::análisis de sistemas::técnica Delfos; DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::niño; ENFERMEDADES::enfermedades del sistema nervioso::malformaciones del sistema nervioso::defectos del tubo neural::malformación de Arnold-Chiari; Otros calificadores::Otros calificadores::/terapia
Springer
Neurological Sciences;43
https://doi.org/10.1007/s10072-021-05317-9
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
Articles científics - HVH [3439]
