dc.contributor
Institut Català de la Salut
dc.contributor
[Baklund IH, Dammen T, Moum TÅ] Department of Behavioural Medicine, Faculty of Medicine, University of Oslo, 0315 Oslo, Norway. [Kristiansen W, Duarte DS] CFS/ME Center, Division of Medicine, Oslo University Hospital, 0318 Oslo, Norway. [Castro-Marrero J] Unitat de Síndrome de Fatiga Crònica/Encefalomielitis Miàlgica (SFC/EM), Secció de Reumatologia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Baklund, Ingrid H.
dc.contributor.author
Dammen, Toril
dc.contributor.author
Moum, Torbjørn Åge
dc.contributor.author
Kristiansen, Wenche
dc.contributor.author
Duarte, Daysi Sosa
dc.contributor.author
Castro Marrero, Jesus
dc.date.accessioned
2025-10-24T08:51:20Z
dc.date.available
2025-10-24T08:51:20Z
dc.date.issued
2022-01-31T11:00:09Z
dc.date.issued
2022-01-31T11:00:09Z
dc.identifier
Baklund IH, Dammen T, Moum TÅ, Kristiansen W, Duarte DS, Castro-Marrero J, et al. Evaluating Routine Blood Tests According to Clinical Symptoms and Diagnostic Criteria in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. J Clin Med. 2021 Jul;10(14):3105.
dc.identifier
https://hdl.handle.net/11351/6936
dc.identifier
10.3390/jcm10143105
dc.identifier
000676202900001
dc.identifier.uri
http://hdl.handle.net/11351/6936
dc.description.abstract
Creatina quinasa; Encefalomielitis miàlgica/síndrome de fatiga crònica; Anàlisis de sang de rutina
dc.description.abstract
Creatina quinasa; Encefalomielitis miálgica/síndrome de fatiga crónica; Análisis de sangre de rutina
dc.description.abstract
Creatine kinase; Myalgic encephalomyelitis/chronic fatigue syndrome; Routine blood tests
dc.description.abstract
There is a lack of research regarding blood tests within individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and between patients and healthy controls. We aimed to compare results of routine blood tests between patients and healthy controls. Data from 149 patients diagnosed with ME/CFS based on clinical and psychiatric evaluation as well as on the DePaul Symptom Questionnaire, and data from 264 healthy controls recruited from blood donors were compared. One-way ANCOVA was conducted to examine differences between ME/CFS patients and healthy controls, adjusting for age and gender. Patients had higher sedimentation rate (mean difference: 1.38, 95% CI: 0.045 to 2.714), leukocytes (mean difference: 0.59, 95% CI: 0.248 to 0.932), lymphocytes (mean difference: 0.27, 95% CI: 0.145 to 0.395), neutrophils (mean difference: 0.34, 95% CI: 0.0 89 to 0.591), monocytes (mean difference: 0.34, 95% CI: 0.309 to 0.371), ferritin (mean difference: 28.13, 95% CI: −1.41 to 57.672), vitamin B12 (mean difference: 83.43, 95% CI: 62.89 to 124.211), calcium (mean difference: 0.02, 95% CI: −0.02 to 0.06), alanine transaminase (mean difference: 3.30, 95% CI: −1.37 to -7.971), low-density lipoproteins (mean difference: 0.45, 95% CI: 0.104 to 0.796), and total proteins (mean difference: 1.53, 95% CI: −0.945 to 4.005) than control subjects. The patients had lower potassium levels (mean difference: 0.11, 95% CI: 0.056 to 0.164), creatinine (mean difference: 2.60, 95% CI: 0.126 to 5.074) and creatine kinase (CK) (mean difference: 37.57, 95% CI: −0.282 to 75.422) compared to the healthy controls. Lower CK and creatinine levels may suggest muscle damage and metabolic abnormalities in ME/CFS patients.
dc.description.abstract
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
dc.format
application/pdf
dc.relation
Journal of Clinical Medicine;10(14)
dc.relation
https://doi.org/10.3390/jcm10143105
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Síndrome de fatiga crònica - Diagnòstic
dc.subject
Sang - Anàlisi
dc.subject
DISEASES::Virus Diseases::Fatigue Syndrome, Chronic
dc.subject
Other subheadings::Other subheadings::/diagnosis
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Hematologic Tests
dc.subject
Other subheadings::Other subheadings::/methods
dc.subject
ENFERMEDADES::virosis::síndrome de fatiga crónica
dc.subject
Otros calificadores::Otros calificadores::/diagnóstico
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::diagnóstico::técnicas y procedimientos diagnósticos::técnicas de laboratorio clínico::pruebas hematológicas
dc.subject
Otros calificadores::Otros calificadores::/métodos
dc.title
Evaluating Routine Blood Tests According to Clinical Symptoms and Diagnostic Criteria in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
