dc.contributor
Institut Català de la Salut
dc.contributor
[Vollebregt PF] Department of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands. Blizard Institute, Queen Mary University London, London, UK. [Baeten CIM] Department of Surgery, Groene Hart Hospital, Gouda, the Netherlands. [Drewes AM] Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark. [Marinello F] Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Martelluci J] Emergency Sugery/Pelvic Floor Center, Careggi University Hospital, Florence, Italy. Collegium Medicum, SAN University, Lodz, Poland. [Mekhael M] Department of Surgery, Aarhus University Hospital, Aarhus, Denmark
dc.contributor
Vall d'Hebron Barcelona Hospital Campus
dc.contributor.author
Vollebregt, Paul
dc.contributor.author
Baeten, Coen
dc.contributor.author
Drewes, Asbjørn
dc.contributor.author
Marinello, Franco
dc.contributor.author
Martelluci, Jacopo
dc.contributor.author
Mekhael, Mira
dc.date.accessioned
2026-03-09T08:11:37Z
dc.date.available
2026-03-09T08:11:37Z
dc.date.issued
2026-03-04T07:24:03Z
dc.date.issued
2026-03-04T07:24:03Z
dc.identifier
Vollebregt PF, Baeten CIM, Drewes AM, Marinello F, Martelluci J, Mekhael M, et al. Transanal irrigation: Bridging the gap in treatment for chronic constipation and/or faecal incontinence—A systematic review and management guidance. Color Dis. 2025 Nov;27(11):e70274.
dc.identifier
http://hdl.handle.net/11351/14298
dc.identifier
10.1111/codi.70274
dc.identifier.uri
https://hdl.handle.net/11351/14298
dc.description.abstract
Constipation; Faecal incontinence; Irrigation
dc.description.abstract
Estreñimiento; Incontinencia fecal; Irrigación
dc.description.abstract
Restrenyiment; Incontinència fecal; Irrigació
dc.description.abstract
Aim
The aims of the study were to: (1) update a systematic review on the efficacy of transanal irrigation (TAI) in patients with chronic constipation (CC) and/or faecal incontinence (FI); (2) provide guidance on the position of TAI in the treatment pathway of CC and FI; and (3) discuss knowledge gaps and areas of future research.
Method
A collaborative of 11 experts (gastroenterologists, colorectal surgeons, and clinical scientists) from eight European countries was established. The expert group was divided into three main groups, with each group leading a specific section (systematic review, treatment pathway, and knowledge gaps). A previously published systematic review on TAI was updated by conducting an additional search on 12 April 2025. Studies on TAI in specific subgroups (neurogenic bowel dysfunction, low anterior resection syndrome) were excluded.
Results
Sixteen studies involving 1567 (range 16–507) patients were included. Only one underpowered randomised trial was performed, which demonstrated that high-volume TAI may be more effective than low-volume TAI in patients with CC. Most other studies (observational) showed improvement in symptoms and/or quality of life to some extent, with a large variation in outcomes used. Treatment discontinuation was reported in 3–57% of patients. The position of TAI in the treatment pathway of CC and FI was proposed, and 13 knowledge gaps were provided.
Conclusion
TAI may be an effective treatment in patients with CC and/or FI. There is a need for randomised controlled trials to study its efficacy and current knowledge gaps.
dc.description.abstract
Paul F. Vollebregt received financial support from Coloplast A/S to write the manuscript.
dc.format
application/pdf
dc.relation
Colorectal Disease;27(11)
dc.relation
https://doi.org/10.1111/codi.70274
dc.rights
Attribution 4.0 International
dc.rights
http://creativecommons.org/licenses/by/4.0/
dc.rights
info:eu-repo/semantics/openAccess
dc.subject
Irrigació (Medicina)
dc.subject
Restrenyiment - Tractament
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Incontinència fecal - Tractament
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DISEASES::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Digestive::Constipation
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Other subheadings::Other subheadings::/therapy
dc.subject
DISEASES::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Rectal Diseases::Fecal Incontinence
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Other subheadings::Other subheadings::/therapy
dc.subject
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Therapeutics::Physical Therapy Modalities::Hydrotherapy::Therapeutic Irrigation
dc.subject
ENFERMEDADES::afecciones patológicas, signos y síntomas::signos y síntomas::signos y síntomas digestivos::estreñimiento
dc.subject
Otros calificadores::Otros calificadores::/terapia
dc.subject
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades gastrointestinales::enfermedades intestinales::enfermedades del recto::incontinencia fecal
dc.subject
Otros calificadores::Otros calificadores::/terapia
dc.subject
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::terapéutica::modalidades de fisioterapia::hidroterapia::irrigación terapéutica
dc.title
Transanal irrigation: Bridging the gap in treatment for chronic constipation and/or faecal incontinence—A systematic review and management guidance
dc.type
info:eu-repo/semantics/article
dc.type
info:eu-repo/semantics/publishedVersion
